With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.130-03-0,Benzo[b]thiophen-3(2H)-one,as a common compound, the synthetic route is as follows.
General procedure: Under an inert atmosphere of argon, a solution of 9 mmol of Component 4 or Component 5 together with 5 mmol of thioindoxyl in 15 mL of methanol was vigorously stirred and to which small portions of Na2CO3 was added. After 1 h of stirring at 45 C, the dark red residue was filtered and successively and intensively washed with methanol and cold water. The resulting precipitate was filtered and purified by silica gel column chromatography (ethyl acetate:hexane 1:2)., 130-03-0
The synthetic route of 130-03-0 has been constantly updated, and we look forward to future research findings.
Reference：
Article; Hosseinnezhad, Mozhgan; Moradian, Siamak; Gharanjig, Kamaladin; Dyes and Pigments; vol. 123; (2015); p. 147 – 153;,
Benzothiophene – Wikipedia
Benzothiophene | C8H6S – PubChem