22913-24-2, Methyl benzo[b]thiophene-2-carboxylate is a benzothiophene compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
22913-24-2, 84 g (0.438 mol) of methyl benzothiophene-2-carboxylate (compare, for example, J. Org. Chem. 37. 3224 [1972]) in 218 ml of ethanol and 36.8 g (0.656 mol) of potassium hydroxide in 100 ml of water are combined, and the mixture is stirred for 4 hours at reflux temperature. For working up, the reaction mixture is allowed to cool, the ethanol is then distilled off in vacuo, the aqueous residue is washed once using diethyl ether, and subsequently acidified with dilute hydrochloric acid, and precipitate which has settled out is filtered off with suction, washed once with water and dried. 60.1 g (77% of theory) of benzothiophene-2-carboxylic acid of melting point >220 C. are obtained. The following benzothiophene-2-carboxamide S,S-dioxides of the general formula (I) STR12 are obtained in a corresponding manner and following the general preparation instructions:
The synthetic route of 22913-24-2 has been constantly updated, and we look forward to future research findings.
Reference：
Patent; Bayer Aktiengesellschaft; US5244893; (1993); A;,
Benzothiophene – Wikipedia
Benzothiophene | C8H6S – PubChem