Healthcare careers for chemists are once again largely based in laboratories, although increasingly there is opportunity to work at the point of care, helping with patient investigation. Product Details of 5394-13-8
The invention provides a method for preparing thioester through oxomercapto acetic acid. In the presence of a palladium catalyst, a phosphine ligand and an organic solvent, the corresponding thioester is produced by decarboxylation of an/oxomercapto acetic acid compound with an aryl iodide or an unsaturated bond-containing compound after decarboxylation. The method provided by the invention can realize high-efficiency catalytic conversion at room temperature or under heating, has mild reaction conditions, is simple to operate, does not need extra alkali and other additives, simplifies the treatment means, meets the requirements of developing green environment-friendly chemistry, and has universality and higher chemical selectivity. The method can be successfully applied to a functional group modification scheme for complex molecules, is used for optimizing the synthesis strategy of part of drug molecules, improves the synthesis efficiency, reduces the cost, and has industrial synthesis value and prospect. (by machine translation)
The design and synthesis of related molecules that are more effective, more selective, and less toxic than aspirin are important objectives of biomedical research.Keep reading other articles of 5394-13-8. Product Details of 5394-13-8”
Reference：
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem