The reaction of an aromatic heterocycle with a proton is called a protonation. One of articles about this theory is 《Directed Nickel-Catalyzed Diastereoselective Reductive Difunctionalization of Alkenyl Amines》. Authors are Zhao, Lei; Meng, Xiao; Zou, Yifeng; Zhao, Junsong; Wang, Lili; Zhang, Lanlan; Wang, Chao.The article about the compound:Methyl 3-bromopropanoatecas:3395-91-3,SMILESS:O=C(OC)CCBr).COA of Formula: C4H7BrO2. Through the article, more information about this compound (cas:3395-91-3) is conveyed.
We report herein an intermol. syn-arylalkylation and alkenylalkylation of alkenyl amines with two different organohalides (iodides and bromides) using Ni(II) catalyst. The cleavable bidentate quinolinamide was utilized after extensive directing group screening to enable olefin difunctionalization with high levels of regio-, chemo-, and diastereocontrol. This general and practical protocol was compatible with α- or β-substituted terminal alkenes and internal alkenes, providing rapid access to branched aliphatic amines bearing two skipped and vicinal stereocenters with high diastereoselectivities that would otherwise be difficult to synthesize.
From this literature《Directed Nickel-Catalyzed Diastereoselective Reductive Difunctionalization of Alkenyl Amines》,we know some information about this compound(3395-91-3)COA of Formula: C4H7BrO2, but this is not all information, there are many literatures related to this compound(3395-91-3).
Reference:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem