Related Products of 88-15-3In 2019 ,《A facile synthesis of highly fluorescent pyrido[2,3-d]pyrimidines and 1,8-naphthyridines via oxazine transformation and enaminic addition reactions》 appeared in Journal of the Iranian Chemical Society. The author of the article were El-Sayed, Hassan A.; Morsy, Hesham A.. The article conveys some information:
The synthesis and fluorescence properties of highly substituted bicyclic pyridine derivatives I (Ar = 4-ClC6H4; R = H, CH3, C6H5, 2,4-Cl2C6H3) and 2,2′-(1,3-phenylene)bis(5-(4-chlorophenyl)-7-(thien-2-yl)pyrido[2,3-d]pyrimidin-4(3H)-one), II (R1R2 = -(CH2)4-, -C(O)CH2C(CH3)2CH2-; R1 = C(O)CH3, C6H5; R2 = CH3) and III (R3 = H, SH) are described. The compounds 2-substituted-4-oxo-pyrido[2,3-d]pyrimidines I (Ar = 4-ClC6H4; R = H, CH3, C6H5, 2,4-Cl2C6H3) and 2,2′-(1,3-phenylene)bis(5-(4-chlorophenyl)-7-(thien-2-yl)pyrido[2,3-d]pyrimidin-4(3H)-one) resulted from the acylation reaction of α-aminonicotinonitrile IV with aroyl chlorides RC(O)Cl and isophthaloyl dichloride, di-Et malonate, Et morpholine-4-carboxylate, acetic anhydride or formic acid under solvent-free conditions. The [4 + 2] cyclocondensation and cycloaddition reactions of compound IV with formamide and ammonium thiocyanate tolerated the fused pyrimidines, III resp. Finally, the Friedlander-like reaction was applied for the synthesis of 1,8-naphthyridines II via reaction of compound IV with cyclohexanone, dimedone, acetyl acetone and benzyl Me ketone, resp., under AlCl3 catalysis. The fluorescence spectroscopic data of some synthesized compounds measured and significant results were observed The experimental process involved the reaction of 1-Thiophen-2-yl-ethanone(cas: 88-15-3Related Products of 88-15-3)
1-Thiophen-2-yl-ethanone(cas: 88-15-3) belongs to thiophenes. Reflecting their high stabilities, thiophenes arise from many reactions involving sulfur sources and hydrocarbons, especially unsaturated ones. Thiophenes are classically prepared by the reaction of 1,4-diketones, diesters, or dicarboxylates with sulfidizing reagents such as P4S10 such as in the Paal-Knorr thiophene synthesis. Related Products of 88-15-3
Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem