A Transition-Metal-Free One-Pot Cascade Process for Transformation of Primary Alcohols (RCH2OH) to Nitriles (RCN) Mediated by SO2F2 was written by Jiang, Ying;Sun, Bing;Fang, Wan-Yin;Qin, Hua-Li. And the article was included in European Journal of Organic Chemistry in 2019.Computed Properties of C9H5NS This article mentions the following:
Primary (benzylic) alcs. underwent transition-metal-free one-pot cascade process with SO2F2, K2CO3, and NH2OH·HCl in DMSO to yield nitriles without introducing an addnl. carbon atom. In the experiment, the researchers used many compounds, for example, Benzo[b]thiophene-2-carbonitrile (cas: 55219-11-9Computed Properties of C9H5NS).
Benzo[b]thiophene-2-carbonitrile (cas: 55219-11-9) belongs to benzothiophene derivatives. Benzothiophene scaffolds are of great importance due to its increased presence in bioactive molecules. It is found within the chemical structures of pharmaceutical drugs such as zileuton, raloxifene, and sertaconazole, and also BTCP.Computed Properties of C9H5NS
Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem