Aminobenzoannulated hetero- and carbocycles from 2-azahepta-2,4-dien-6-ynyllithium compounds: scope and limitation of a novel benzoannulation reaction was written by Lyaskovskyy, Volodymyr;Froehlich, Roland;Wuerthwein, Ernst-Ulrich. And the article was included in Synthesis in 2007.Recommanded Product: 6287-82-7 This article mentions the following:
Deprotonation of the N-benzylhetarylmethanimines, e.g. I (R1 = n-Bu, Ph), at -78 °C with subsequent warming to room temperature over 16 h and treatment with electrophiles furnished polysubstituted aminobenzoannulated heterocycles, e.g. II (R2 = H, Me), in good to excellent yields. In a similar fashion, the deprotonation of the N-allyl-2-(alk-1-ynyl)phenylmethanimines led to 1-amino-2-vinylnaphthalenes in moderate yields. The reaction of N-[(trimethylsilyl)methyl] imine of o-(phenylethynyl)benzaldehyde afforded naphthalen-1-amine unsubstituted at the ortho-position after removal of the trimethylsilyl group. The deprotonation of N-benzyl imine of o-(trimethylsilylethynyl)benzaldehyde gave none of expected amines, but the substituted imine, N-benzylidene-α-methyl-2-(trimethylsilyl)benzylamine, whose structure was identified using 2D NMR spectroscopy. In the experiment, the researchers used many compounds, for example, 2,3-Dibromobenzo[b]thiophene (cas: 6287-82-7Recommanded Product: 6287-82-7).
2,3-Dibromobenzo[b]thiophene (cas: 6287-82-7) belongs to benzothiophene derivatives. Functionalized benzothiophenes are important constructs found in molecules with wide ranging biological activity and in organic materials. It is found within the chemical structures of pharmaceutical drugs such as raloxifene, zileuton, and sertaconazole, and also BTCP.Recommanded Product: 6287-82-7
Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem