Day: February 22, 2023

Synthesis and Electrochemical Performance of Spheroid LiNi_1/3Co_1/3Mn_1/3O₂ in the Electrolyte Modified by Ethylene Sulfate and Methylene Methanedisulfonate was written by Cui, Yongli;Yang, Chao;Zhuang, Zhiheng;Wang, Mingzhen;Zhuang, Quanchao. And the article was included in Journal of Inorganic and Organometallic Polymers and Materials in 2018.Electric Literature of C2H4O4S This article mentions the following:

In this study, spheroid LiNi_1/3Co_1/3Mn_1/3O₂ (NCM111) cathode material were synthesized using LiOH with Ni_0.5Co_0.2Mn_0.3(OH)₂ precursor by a simple solid-state reaction, and characterized by X-ray diffraction and SEM. Electrochem. behavior of NCM111 was investigated by electrochem. impedance spectroscopy (EIS) combining with cyclic voltammogram (CV) and charge/discharge test in the 1 M LiPF₆-EC:EMC electrolyte with ethylene sulfate (DTD) and methylene methanedisulfonate (MMDS) additives either singly or in combination with high cutoff voltage of 3.0-4.5 V at room temperature of 25 °C or elevated temperature of 55 °C. It was found that DTD additive can increase the initial coulombic efficiency of NCM111, and the spheroid NCM111 can obtain the maximum initial discharge capacity of 177.81 mAh/g with the 2 wt% DTD, and keep 92.29% capacity retention after 80 cycles. The MMDS additives would decrease the initial discharge capacity of the NCM111, and enhance significantly long cycle life of the NCM111 with the capacity retention of 99.23% over 80 cycles at high voltage of 4.5 V. The additive combination 2 wt% DTD + 1 wt% MMDS was an optimal additive combination, demonstrating the 102.2% capacity retention over 80 cycles at room temperature and the 94.2% capacity retention over 70 cycles at elevated temperature of 55 °C. EIS results revealed that the additive blend of 2 wt% DTD + 1 wt% MMDS can drastically lower the kinetics impedance and suppress the growth rate of R_ct for the NCM111 electrode. In the experiment, the researchers used many compounds, for example, 1,3,2-Dioxathiolane 2,2-dioxide (cas: 1072-53-3Electric Literature of C2H4O4S).

1,3,2-Dioxathiolane 2,2-dioxide (cas: 1072-53-3) belongs to benzothiophene derivatives. Functionalized benzothiophenes are important constructs found in molecules with wide ranging biological activity and in organic materials. It is found within the chemical structures of pharmaceutical drugs such as raloxifene, zileuton, and sertaconazole, and also BTCP.Electric Literature of C2H4O4S

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Sustainable synthesis of pyrazoles using alcohols as the primary feedstock by an iron catalyzed tandem C-C and C-N coupling approach was written by Mondal, Rakesh;Guin, Amit Kumar;Pal, Subhasree;Mondal, Sucheta;Paul, Nanda D.. And the article was included in Organic Chemistry Frontiers in 2022.Category: benzothiophene This article mentions the following:

Authors report two new efficient iron-catalyzed synthetic strategies for multicomponent synthesis of tri-substituted pyrazoles using biomass-derived alcs. as the primary feedstock. A well-defined, bench stable, and easy to prepare Fe(II)-catalyst bearing a tridentate pincer 2-(phenyldiazenyl)-1,10-phenanthroline was used as the catalyst. A wide variety of tri-substituted pyrazoles were prepared via dehydrogenative coupling of alcs., and aryl hydrazines with secondary alcs. and alkynes, resp. These methods eliminate the potential use of any pre-functionalized starting materials, noble metal catalysts, oxidants, or additives producing various substituted pyrazoles in moderate to good isolated yields via sequential C-C and C-N bond formation. A series of control experiments and spectroscopic studies were performed to understand the plausible mechanism of these multicomponent reactions. In the experiment, the researchers used many compounds, for example, 2-Ethynylthiophene (cas: 4298-52-6Category: benzothiophene).

2-Ethynylthiophene (cas: 4298-52-6) belongs to benzothiophene derivatives. Benzothiophene scaffolds are of great importance due to its increased presence in bioactive molecules. It has been used as a raw material for the synthesis of biologically active structures and is found in pharmaceuticals such as leukotriene synthesis inhibitors and antifungals, as well as in many natural products.Category: benzothiophene

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Anti-biofilm Agents against Pseudomonas aeruginosa: A Structure-Activity Relationship Study of C-Glycosidic LecB Inhibitors was written by Sommer, Roman;Rox, Katharina;Wagner, Stefanie;Hauck, Dirk;Henrikus, Sarah S.;Newsad, Shelby;Arnold, Tatjana;Ryckmans, Thomas;Broenstrup, Mark;Imberty, Anne;Varrot, Annabelle;Hartmann, Rolf W.;Titz, Alexander. And the article was included in Journal of Medicinal Chemistry in 2019.Related Products of 69815-97-0 This article mentions the following:

Biofilm formation is a key mechanism of antimicrobial resistance. We have recently reported two classes of orally bioavailable C-glycosidic inhibitors of the Pseudomonas aeruginosa lectin LecB with antibiofilm activity. They proved efficient in target binding, were metabolically stable, nontoxic, selective, and potent in inhibiting formation of bacterial biofilm. Here, we designed and synthesized six new carboxamides and 24 new sulfonamides for a detailed structure-activity relationship for two clin. representative LecB variants. Sulfonamides generally showed higher inhibition compared to carboxamides, which was rationalized based on crystal structure analyses. Substitutions at the thiophenesulfonamide increased binding through extensive contacts with a lipophilic protein patch. These metabolically stable compounds showed a further increase in potency toward the target and in biofilm inhibition assays. In general, we established the structure-activity relationship for these promising antibiofilm agents and showed that modification of the sulfonamide residue bears future optimization potential. In the experiment, the researchers used many compounds, for example, 4-Methylthiophene-2-sulfonyl chloride (cas: 69815-97-0Related Products of 69815-97-0).

4-Methylthiophene-2-sulfonyl chloride (cas: 69815-97-0) belongs to benzothiophene derivatives. Benzothiophene scaffolds are of great importance due to its increased presence in bioactive molecules. It is found within the chemical structures of pharmaceutical drugs such as raloxifene, zileuton, sertaconazole, and also BTCP.Related Products of 69815-97-0

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Improved methods on filling reaction tubes and sample preparation of EA1110 element analyzer at CHN model was written by Wu, Bing;Cao, Xiangqian. And the article was included in Suzhou Daxue Xuebao, Ziran Kexueban in 2010.SDS of cas: 7128-64-5 This article mentions the following:

An improved method on filling reaction tubes in an EA1110 element analyzer at CHN model is stated. In a combustion tube, silver-wire, Cr₂O₃ and Co₃O₄ + Ag are filled in order, and Cu is the unique reagent in a reduction tube. Relevant actions for sample preparation are taken according to characteristics of samples. In this way, the accurate testing-results are ensured, and the average usage times of the combustion tube and the reduction tube have been increased by 24% and 59%, resp. Correspondingly, the efficiency of the element analyzer is enhanced. In the experiment, the researchers used many compounds, for example, 2,5-Bis(5-(tert-butyl)benzo[d]oxazol-2-yl)thiophene (cas: 7128-64-5SDS of cas: 7128-64-5).

2,5-Bis(5-(tert-butyl)benzo[d]oxazol-2-yl)thiophene (cas: 7128-64-5) belongs to benzothiophene derivatives. Benzothiophene is relatively a stable molecule. The core structure is a part of various pharmaceutical substances and natural products. It is found within the chemical structures of pharmaceutical drugs such as raloxifene, zileuton, sertaconazole, and also BTCP.SDS of cas: 7128-64-5

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Selective Ni-catalyzed cross-electrophile coupling of alkynes, fluoroalkyl halides and vinyl halides was written by Dai, Yubei;Wang, Fang;Zhu, Shengqing;Chu, Lingling. And the article was included in Chinese Chemical Letters in 2022.Electric Literature of C6H4S This article mentions the following:

A Ni-catalyzed three-component cross-electrophile coupling of alkynes with alkenyl halides and fluoroalkyl halides to generate fluoroalkyl-incorporated 1,3-dienes was reported. This mild and operationally simple protocol was distinguished by its broad substrate scope and excellent chemo-, regio- and stereoselectivity, offering a new and organometallic agent-free platform for the construction of fluoroalkyl-incorporated diene motifs. Preliminary mechanistic studies were conducted to probe the potential reaction pathway. In the experiment, the researchers used many compounds, for example, 2-Ethynylthiophene (cas: 4298-52-6Electric Literature of C6H4S).

2-Ethynylthiophene (cas: 4298-52-6) belongs to benzothiophene derivatives. Benzothiophene is used as starting material for the synthesis of bioactive molecules. The core structure is a part of various pharmaceutical substances and natural products. It is found within the chemical structures of pharmaceutical drugs such as raloxifene, zileuton, sertaconazole, and also BTCP.Electric Literature of C6H4S

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Fabrication of Robust Spatially Resolved Photochromic Patterns on Cellulose Papers by Covalent Printing for Anticounterfeiting Applications was written by Bretel, Guillaume;Le Grognec, Erwan;Jacquemin, Denis;Hirose, Takashi;Matsuda, Kenji;Felpin, Francois-Xavier. And the article was included in ACS Applied Polymer Materials in 2019.Application In Synthesis of 2-Methylbenzo[b]thiophene This article mentions the following:

Despite its millennial age, cellulose paper remains the preferred material for domestic and professional printings, covering applications from simple office paperwork to fiducial solutions such as bills, passports, and head letters. The creation of robust photochromic patterns on cellulose papers for anticounterfeiting applications is an important and still partially unaddressed challenge. In this contribution, we report the covalent printing of dibenzothienylethenes as photochromic compounds through a spatially controlled light-mediated thiol-X ligations. Photophys. and theor. studies provide evidence for a reversible photochromism behavior, not affected significantly by the polar environment of the cellulose matrix, and demonstrates a high fatigue resistance over 18 successive write-erase cycles. The strong coloration-discoloration switch can be easily followed by a direct naked-eye readout. In the experiment, the researchers used many compounds, for example, 2-Methylbenzo[b]thiophene (cas: 1195-14-8Application In Synthesis of 2-Methylbenzo[b]thiophene).

2-Methylbenzo[b]thiophene (cas: 1195-14-8) belongs to benzothiophene derivatives. Benzothiophene finds use in research as a starting material for the synthesis of larger, usually bioactive structures. It is also used in the manufacturing of dyes such as thioindigo.Application In Synthesis of 2-Methylbenzo[b]thiophene

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Influence of Glutathione Oxidation and pH on Thermal Formation of Maillard-Type Volatile Compounds was written by Tai, Chao-Ying;Ho, Chi-Tang. And the article was included in Journal of Agricultural and Food Chemistry in 1998.Safety of 3-Ethylthiophene This article mentions the following:

The Maillard-type volatile compounds obtained from the reaction of glutathione and glucose were mainly furans, carbonyl compounds, and sulfur-containing compounds including thiophenes, thiazoles, and cyclic polysulfides. Both pH 8.0 and 6.0 were favorable conditions for sulfur-containing compound formation, whereas acidic conditions were favorable for furan and derivative formation. The reaction between glutathionesulfonic acid, an oxidized form of glutathione, and glucose primarily produced furans, carbonyl compounds, pyrazines, and pyrroles. Furans dominated the products obtained from the reactions at pH 6.0 and 8.0. Pyrazines increased as the reaction pH increased. The disappearance of sulfur-containing compounds in the products of glutathionesulfonic acid and glucose reaction systems indicated glutathionesulfonic acid could not provide hydrogen sulfide for the reaction. In the experiment, the researchers used many compounds, for example, 3-Ethylthiophene (cas: 1795-01-3Safety of 3-Ethylthiophene).

3-Ethylthiophene (cas: 1795-01-3) belongs to benzothiophene derivatives. Benzothiophene finds use in research as a starting material for the synthesis of larger, usually bioactive structures. Its aromaticity makes it relatively stable, although as a heterocycle, it has reactive sites which allow for functionalization.Safety of 3-Ethylthiophene

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Development of a Scalable Route for a Highly Polar Heterocyclic Aminocyclopropyl Building Block was written by Schafer, Gabriel;Ahmetovic, Muhamed;Fleischer, Tony;Abele, Stefan. And the article was included in Organic Process Research & Development in 2020.Quality Control of 1,3,2-Dioxathiolane 2,2-dioxide This article mentions the following:

A robust and scalable route toward key heterocyclic building block 1-(pyrimidin-2-yl)cyclopropan-1-amine hydrochloride from cyclopropanated starting material 1-amino-1-cyclopropanecarbonitrile hydrochloride was successfully developed. The key to success was the construction of a pyrimidine ring via cyclization from an amidine intermediate and a bench-stable 2-chloro vinamidinium hexafluorophosphate salt. The cyclization was performed under mild conditions, and the resulting 4-chloropyrimidine derivative was isolated in high yield and purity. The final hydrogenation was intensively optimized: A combination of Pd(OH)₂/C as a catalyst and NaOMe as a base at 1 bar H₂ pressure in MeOH simultaneously cleaved the Cbz group and dechlorinated the pyrimidine ring while at the same time suppressing the over-reduction of the pyrimidine ring to below 1.0%. After acidification with HCl, followed by removal of the catalyst and NaCl by filtration, the final product was isolated in high yield and purity as a bench-stable off-white solid. The overall yield of the five-step sequence was 57%. In the experiment, the researchers used many compounds, for example, 1,3,2-Dioxathiolane 2,2-dioxide (cas: 1072-53-3Quality Control of 1,3,2-Dioxathiolane 2,2-dioxide).

1,3,2-Dioxathiolane 2,2-dioxide (cas: 1072-53-3) belongs to benzothiophene derivatives. Benzothiophene is used as starting material for the synthesis of bioactive molecules. The core structure is a part of various pharmaceutical substances and natural products. It is also used in the manufacturing of dyes such as thioindigo.Quality Control of 1,3,2-Dioxathiolane 2,2-dioxide

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Iron-catalyzed [3 + 2 + 1] annulation of 2-aminobenzimidazoles/3-aminopyrazoles and aromatic alkynes using N,N-dimethylaminoethanol as a one carbon synthon for the synthesis of pyrimido[1,2-a]benzimidazoles and pyrimido[1,2-b]indazoles was written by Qin, Zemin;Zhang, Ruiqin;Ying, Shenpeng;Ma, Yongmin. And the article was included in Organic Chemistry Frontiers in 2022.Application In Synthesis of 2-Ethynylthiophene This article mentions the following:

A simple and efficient method for the synthesis of pyrimido[1,2-a]benzimidazoles I (R = R¹ = H, Cl; R² = Ph, 1-naphthyl, 2-thienyl, etc.; R³ = H, Me, Ph, thiophen-3-yl, etc.) and pyrimido[1,2-b]indazoles II (R⁴ = H, Cl, F; R⁵ = H, Me, Br) from 2-aminobenzimidazoles/3-aminoindazoles, alkynes R²CCR³ and N,N-dimethylaminoethanol by a three-component [3+2+1] annulation catalyzed by FeCl₃ has been established, where N,N-dimethylaminoethanol was applied as a methine source. Good tolerance of the reaction makes this method applicable to construct biol. active pyrimido[1,2-a]benzimidazoles and pyrimido[1,2-b]indazoles. In addition, regioselective aryl substituted pyrimido[1,2-a]benzimidazoles were synthesized in the presence of TfOH. Replacement of alkynes with acetaldehydes gave the same pyrimido[1,2-a]benzimidazoles and pyrimido[1,2-b]indazoles. In the experiment, the researchers used many compounds, for example, 2-Ethynylthiophene (cas: 4298-52-6Application In Synthesis of 2-Ethynylthiophene).

2-Ethynylthiophene (cas: 4298-52-6) belongs to benzothiophene derivatives. Benzothiophene scaffolds are of great importance due to its increased presence in bioactive molecules. It is found within the chemical structures of pharmaceutical drugs such as raloxifene, zileuton, and sertaconazole, and also BTCP.Application In Synthesis of 2-Ethynylthiophene

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Benzylic Arylation of 2-Methyl-5-membered Heterocycles Using TMP-Bases was written by Duez, Stephanie;Steib, Andreas K.;Knochel, Paul. And the article was included in Organic Letters in 2012.Product Details of 1195-14-8 This article mentions the following:

A new general Pd-catalyzed arylation of various 2-methyl-5-membered heterocycles is reported. This novel method requires Li-, Mg-, or Zn-TMP bases and allows selective metalation of the benzylic position. Subsequent Negishi cross-coupling provides the corresponding arylated heterocycles. In the experiment, the researchers used many compounds, for example, 2-Methylbenzo[b]thiophene (cas: 1195-14-8Product Details of 1195-14-8).

2-Methylbenzo[b]thiophene (cas: 1195-14-8) belongs to benzothiophene derivatives. Functionalized benzothiophenes are important constructs found in molecules with wide ranging biological activity and in organic materials. It is found within the chemical structures of pharmaceutical drugs such as raloxifene, zileuton, and sertaconazole, and also BTCP.Product Details of 1195-14-8

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem