Day: February 22, 2023

Simultaneous Immobilization of CO₂ and H₂S by Propargyl Amines under Mild Conditions: Efficient Synthesis of Thiazolidine-2-ones was written by Wu, Jiakai;He, Rongting;Cheng, Siliu;Han, Limin;Hong, Hailong;Zhu, Ning. And the article was included in ACS Sustainable Chemistry & Engineering in 2022.Application In Synthesis of 2-Ethynylthiophene This article mentions the following:

A series of thiazolidine-2-one derivatives were synthesized by a three-component reaction of carbon dioxide, hydrogen sulfide, and propargyl amines under mild conditions. The simultaneous incorporation of carbon dioxide and hydrogen sulfide into the same organic product was realized. Moreover, a reaction mechanism was proposed based on the detailed NMR and FTIR study, which indicated that propargyl amine reacted with CO₂ first to form carbamate, followed by O/S exchange with H₂S to form thiocarbamate and the final cyclization of thiocarbamate to form thiazolidine-2-one. In the experiment, the researchers used many compounds, for example, 2-Ethynylthiophene (cas: 4298-52-6Application In Synthesis of 2-Ethynylthiophene).

2-Ethynylthiophene (cas: 4298-52-6) belongs to benzothiophene derivatives. Benzothiophene is a fused ring compound of thiophene ring and benzene ring, which is an important class of heterocycles with advantageous structures. The different substitution patterns in these heterocycles offer new opportunities for drug discovery and other applications in materials science.Application In Synthesis of 2-Ethynylthiophene

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Construction of Stable Donor-Acceptor Type Covalent Organic Frameworks as Functional Platform for Effective Perovskite Solar Cell Enhancement was written by Li, Zhongping;Zhang, Zhenwei;Nie, Riming;Li, Chunzhi;Sun, Qikun;Shi, Wei;Chu, Weicun;Long, Yuyang;Li, He;Liu, Xiaoming. And the article was included in Advanced Functional Materials in 2022.Category: benzothiophene This article mentions the following:

Covalent organic frameworks (COFs) as a new class of crystalline, porous materials have attracted extensive attention in the fields of photocatalytic and photovoltaic applications. Generally, donor-acceptor (DA) structures play an important role in the charge separation efficiency of solar cells. In this study, two DA-COFs with high crystallinity, good porosity, and excellent stability are incorporated into the FAPbI₃ layer of perovskite solar cells. This addition of DA-COFs reduces the defect concentration and shallows the defect state. The donor-acceptor system in COFs also possesses strong charge-transfer pathway, which strongly prevents charge recombination to afford more efficient charge separation efficiency. The highest power-conversion efficiency of perovskite solar cells constructed with DA-COFs is 23.19% with excellent humidity stability of the solar cells. Therefore, this work provides a pathway for using DA-COFs to fabricate perovskite solar cells with higher efficiency and stability. In the experiment, the researchers used many compounds, for example, Benzo[1,2-b:3,4-b’:5,6-b”]trithiophene-2,5,8-tricarbaldehyde (cas: 2243590-42-1Category: benzothiophene).

Benzo[1,2-b:3,4-b’:5,6-b”]trithiophene-2,5,8-tricarbaldehyde (cas: 2243590-42-1) belongs to benzothiophene derivatives. Functionalized benzothiophenes are important constructs found in molecules with wide ranging biological activity and in organic materials. The different substitution patterns in these heterocycles offer new opportunities for drug discovery and other applications in materials science.Category: benzothiophene

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

The use of N,N-dimethylformamide-sulfonyl chloride complex for the preparation of thiophenesulfonyl chlorides was written by Sone, Tyo;Abe, Yukio;Sato, Norio;Ebina, Manabu. And the article was included in Bulletin of the Chemical Society of Japan in 1985.Safety of 4-Methylthiophene-2-sulfonyl chloride This article mentions the following:

Thiophenesulfonyl chlorides I (R = H, Me, Cl, Br, iodo, Ph, CH_iPh, CO₂Me; R¹ = SO₂Cl) were prepared in 9-79% yield by treating thiophene with a 1:1 DMF-SO₂Cl₂ complex. Some I (R¹ = HCO) were also formed. Treatment of I (R = R¹ = Me) with the complex yielded sulfonyl chloride II. In the experiment, the researchers used many compounds, for example, 4-Methylthiophene-2-sulfonyl chloride (cas: 69815-97-0Safety of 4-Methylthiophene-2-sulfonyl chloride).

4-Methylthiophene-2-sulfonyl chloride (cas: 69815-97-0) belongs to benzothiophene derivatives. Benzothiophene is relatively a stable molecule. The electrophilic substitution of benzothiophene systems is much less regioselective than that of indoles. Due to its aromaticity, thiophenes do not exhibit the same properties as conventional thioethers.Safety of 4-Methylthiophene-2-sulfonyl chloride

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Fluorine as an ortho-directing group in aromatic metalation: a two step preparation of substituted benzo[b]thiophene-2-carboxylates was written by Bridges, Alexander J.;Lee, Arthur;Maduakor, Emmanuel C.;Schwartz, C. Eric. And the article was included in Tetrahedron Letters in 1992.Synthetic Route of C11H10O3S This article mentions the following:

A simple 2-step synthesis of B-ring substituted benzo[b]thiophene-2-carboxylates from aryl fluorides has been developed. The route involves a selective lithiation ortho to fluorine, followed by formylation, and subsequently, displacement of fluorine with thioglycollate and base-induced ring closure in a single operation. Thus, 3-fluoroiodobenzene was formylated to give 2-fluoro-6-iodobenzaldehyde (I) in 92% yield. I cyclized with Me thioglycolate in DMSO to give iodobenzothiophenecarboxylate II in 81% yield. In the experiment, the researchers used many compounds, for example, Methyl 5-methoxybenzo[b]thiophene-2-carboxylate (cas: 19492-99-0Synthetic Route of C11H10O3S).

Methyl 5-methoxybenzo[b]thiophene-2-carboxylate (cas: 19492-99-0) belongs to benzothiophene derivatives. Benzothiophene is relatively a stable molecule. The core structure is a part of various pharmaceutical substances and natural products. It is also used in the manufacturing of dyes such as thioindigo.Synthetic Route of C11H10O3S

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Thieme Chemistry Journal Awardees – Where are They Now?The Influence of Electron-Withdrawing Groups at the 2- and 2′-Positions of Dibenzothienylethenes on Molecular Switching was written by Hofsaess, Robert;Rombach, David;Wagenknecht, Hans-Achim. And the article was included in Synlett in 2017.Formula: C9H8S This article mentions the following:

Three dibenzothienylethenes that carry a Me, a trifluoromethyl, or a fluoro substituent in the 2- and 2′-position were synthesized in short multistep syntheses, resp. The trifluoromethyl and fluoromethyl substituents significantly improve the absorption properties of the corresponding open and closed isomers (both in the UV-A and in the visible range). The increasing electron deficiency (i) enlarges the portion of the closed and colored diarylethene isomer in the corresponding photostationary states and slows down the closing and opening isomerisation, (ii) the switching reactions, both closing and opening, are slowed down, and (iii) the switching quantum yields are lowered. In the experiment, the researchers used many compounds, for example, 2-Methylbenzo[b]thiophene (cas: 1195-14-8Formula: C9H8S).

2-Methylbenzo[b]thiophene (cas: 1195-14-8) belongs to benzothiophene derivatives. Benzothiophene scaffolds are of great importance due to its increased presence in bioactive molecules. The different substitution patterns in these heterocycles offer new opportunities for drug discovery and other applications in materials science.Formula: C9H8S

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

1,4-Reduction of α,β-Unsaturated Ketones through Rhodium(III)-Catalyzed Transfer Hydrogenation was written by Yu, Xuewen;Wan, Saihong;Zhou, Wang. And the article was included in Synlett.Synthetic Route of C13H10OS This article mentions the following:

A rhodium(III)-catalyzed transfer hydrogenation of unsaturated ketones was developed. The simple catalytic system could be used for the 1,4-reduction of unsaturated cyclic, acyclic ketones, diketones, as well as β-ketoester, and a variety of functional groups were well-tolerated, affording products in moderate to excellent yields. In the experiment, the researchers used many compounds, for example, 3-Phenyl-1-(thiophen-2-yl)prop-2-en-1-one (cas: 3988-77-0Synthetic Route of C13H10OS).

3-Phenyl-1-(thiophen-2-yl)prop-2-en-1-one (cas: 3988-77-0) belongs to benzothiophene derivatives. Benzothiophene is used as starting material for the synthesis of bioactive molecules. The core structure is a part of various pharmaceutical substances and natural products. It is found within the chemical structures of pharmaceutical drugs such as raloxifene, zileuton, and sertaconazole, and also BTCP.Synthetic Route of C13H10OS

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Inhibitors of 15-Prostaglandin Dehydrogenase To Potentiate Tissue Repair was written by Antczak, Monika I.;Zhang, Yongyou;Wang, Changguang;Doran, Jennifer;Naidoo, Jacinth;Voruganti, Sukesh;Williams, Noelle S.;Markowitz, Sanford D.;Ready, Joseph M.. And the article was included in Journal of Medicinal Chemistry in 2017.SDS of cas: 3988-77-0 This article mentions the following:

The enzyme 15-prostaglandin dehydrogenase (15-PGDH) catalyzes the first step in the degradation of prostaglandins including PGE2. It is a neg. regulator of tissue repair and regeneration in multiple organs. Accordingly, inhibitors of 15-PGDH are anticipated to elevate in vivo levels of PGE2 and to promote healing and tissue regeneration. The small mol. SW033291 (1) inhibits 15-PGDH with K_i = 0.1 nM in vitro, doubles PGE2 levels in vivo, and shows efficacy in mouse models of recovery from bone marrow transplantation, ulcerative colitis, and partial hepatectomy. Here we describe optimized variants of 1 with improved solubility, druglike properties, and in vivo activity. In the experiment, the researchers used many compounds, for example, 3-Phenyl-1-(thiophen-2-yl)prop-2-en-1-one (cas: 3988-77-0SDS of cas: 3988-77-0).

3-Phenyl-1-(thiophen-2-yl)prop-2-en-1-one (cas: 3988-77-0) belongs to benzothiophene derivatives. Benzothiophene is relatively a stable molecule. The core structure is a part of various pharmaceutical substances and natural products. It is found within the chemical structures of pharmaceutical drugs such as raloxifene, zileuton, sertaconazole, and also BTCP.SDS of cas: 3988-77-0

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Cascade Oxidative C-H Annulation of Thiophenes: Heck-Type Pathway Enables Concise Access to Thienoacenes was written by Chen, Xingyu;Yang, Yudong;Han, Weiguo;Huang, Quan;Huang, Zhenmei;You, Jingsong. And the article was included in Angewandte Chemie, International Edition in 2021.Safety of 4-Bromobenzo[b]thiophene This article mentions the following:

The pursuit of efficient synthetic route to thienoacenes represents an appealing yet challenging task in the fields of both organic synthetic chem. and organic functional materials. In this work, we disclose a rhodium-catalyzed cascade C-H annulation of phenacyl phosphonium trifluoroacetates with (benzo)thiophenes via a Heck-type pathway to provide a new class of planar thienoacenes such as dithienonaphthopyran I, which involves the formation of three aryl-aryl carbon-carbon bonds and one aryl carbon-oxygen bond in a single operation. The neutral S,O-heteroacenes exhibit superior stabilities and adopt herringbone-like packing modes with efficient π-π stacking in their crystals, suggesting their potential in organic semiconducting materials. This work first exemplifies the superiority of cascade oxidative C-H annulation involving a Heck-type pathway in the development of concise access to heteroacenes. In the experiment, the researchers used many compounds, for example, 4-Bromobenzo[b]thiophene (cas: 5118-13-8Safety of 4-Bromobenzo[b]thiophene).

4-Bromobenzo[b]thiophene (cas: 5118-13-8) belongs to benzothiophene derivatives. Benzothiophene is relatively a stable molecule. The electrophilic substitution of benzothiophene systems is much less regioselective than that of indoles. It is found within the chemical structures of pharmaceutical drugs such as zileuton, raloxifene, and sertaconazole, and also BTCP.Safety of 4-Bromobenzo[b]thiophene

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Photopolymer resins for luminescent three-dimensional printing was written by Wang, Fei;Chong, Yiting;Wang, Fu Ke;He, Chaobin. And the article was included in Journal of Applied Polymer Science in 2017.Recommanded Product: 2,5-Bis(5-(tert-butyl)benzo[d]oxazol-2-yl)thiophene This article mentions the following:

Liquid resins based three-dimensional (3D) printing techniques such as stereolithog. (SLA) and digital light processing (DLP) show higher resolution and accuracy than other printing techniques, but their applications were impeded by the limited materials selection and lack of functions. We here reported the preparation of luminescent resins for DLP-based 3D printing. Homogeneous dispersion of the fluorescent dyes was achieved by small acrylate mols. screening, and the cure depth studies was used to optimize both resin composition and printing parameters setting. In addition, we showed that the optical anal. of absorption and emission spectra is an important tool to reduce the complex mutual-interference of the light absorption of dye, photoinitiator and photo-absorber in the printable resin. We also developed the mater batch technique to tune the emitting colors in the whole visible range, together with white emitting. By using the developed resins, different 3D structures with different emitting colors were successfully printed by DLP technique. These results will further widen the applications of the liquid resins-based 3D printing techniques, and these luminescent resins show highly potential applications in education, lighting, UV converters, and so on. © 2017 Wiley Periodicals, Inc.J. Appl. Polym. Sci. 2017, 134, 44988. In the experiment, the researchers used many compounds, for example, 2,5-Bis(5-(tert-butyl)benzo[d]oxazol-2-yl)thiophene (cas: 7128-64-5Recommanded Product: 2,5-Bis(5-(tert-butyl)benzo[d]oxazol-2-yl)thiophene).

2,5-Bis(5-(tert-butyl)benzo[d]oxazol-2-yl)thiophene (cas: 7128-64-5) belongs to benzothiophene derivatives. Benzothiophenes are valuable heterocycles that are widely used in medicines, agrochemicals, and materials science. It is also used in the manufacturing of dyes such as thioindigo.Recommanded Product: 2,5-Bis(5-(tert-butyl)benzo[d]oxazol-2-yl)thiophene

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Syntheses and properties of five-ring fused azo- and thio-aromatic compounds containing imide substituent was written by Yang, Ning;Qiao, Xiaolan;Fang, Renren;Tao, Jingwei;Hao, Jian;Li, Hongxiang. And the article was included in Huaxue Xuebao in 2016.Synthetic Route of C8H7BO2S This article mentions the following:

Five-ring fused azo- and thio-aromatic compounds 1 and 2 containing imide substituent were designed and synthesized. 3,4-Dibromo-1-(2-ethylhexyl)-1H-pyrrole-2,5-dione reacted with lithium indyl and benzothiophene-3-boronic acid resp., affording intermediates 3 and 4. Compound 3 was intramol. cyclized in the presence of PdCl₂ to give target compound 1. And compound 2 was prepared through intramol. cyclization of intermediate 4 by means of photochem. ring closure reaction and oxidation The physicochem. properties of compounds 1 and 2 were thoroughly investigated with TGA, UV-vis absorption spectra and cyclic voltammetry. Exptl. results showed the introduction of imide substituent not only increased the solubility of compounds 1 and 2, but also decreased their energy levels of the HOMO (HOMO) and the LUMO (LUMO). The HOMO/LUMO energy levels of compounds 1 and 2 are -5.58/-2.25 eV -6.04/-3.51 eV resp. Single crystals of compound 1 were grown through solvent evaporation method in the mixture of dichloromethane and petroleum ether. Single crystal structure revealed compound 1 has a planar conjugated core and forms dimmer in the crystal. Strong π-π intermol. interactions exist in the dimmer, and hydrogen bonds (NH···O=C) are observed among dimmers. The charge carrier mobilities of compounds 1 and 2 were investigated through thin film transistors. The transistors were fabricated with top-contact/bottom-gate device configurations. And thin films were deposited in vacuum on octadecyltrichlorosilane (OTS)-modified Si/SiO₂ substrates. Transistors performance of compound 2 displays obvious p-type performance with a mobility of 2.75 × 10^-3 cm²·V^-1·s^-1. However, compound 1 exhibited no organic field-effect transistor (OFET) behavior. In order to understand the different device performances of compounds 1 and 2, their thin films were investigated by at. force microscopy (AFM) and X-ray diffraction (XRD). AFM images showed that compound 1 formed continuous thin film with small size of microstructures, the existence of grain boundaries hindered the transport of charge carriers in the film. XRD curves revealed that compound 2 formed crystalline thin films. Through the continuity of 2 films was worse than that of 1, the large size of microstructures and the crystalline property of the films facilitated the transport of charge carriers. In the experiment, the researchers used many compounds, for example, Benzo[b]thiophen-3-ylboronic acid (cas: 113893-08-6Synthetic Route of C8H7BO2S).

Benzo[b]thiophen-3-ylboronic acid (cas: 113893-08-6) belongs to benzothiophene derivatives. Benzothiophene is relatively a stable molecule. The core structure is a part of various pharmaceutical substances and natural products. It is also used in the manufacturing of dyes such as thioindigo.Synthetic Route of C8H7BO2S

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem