Insights into the Reactivity of Thiophene: Heterogeneous Alkylation was written by Lucarelli, C.;Giugni, A.;Vaccari, A.. And the article was included in Topics in Catalysis in 2016.Category: benzothiophene This article mentions the following:
The importance of thiophene derivatives in the fine chem. industry lies in the use of this class of mols. as raw materials in the synthesis of drugs, fragrances and pesticides. Nowadays, the synthesis of these mols. is multistep and expensive. The gas phase alkylation of thiophene on solid acid catalysts has been deeply studied by focusing on the possibility to control the product distribution of the reaction, paying particular attention to the relative amount of the 2- and 3-alkylthiophene, kinetic and thermodn. products resp. The difficulties in changing the 2:3 isomer ratio have been justified through the comprehension of thiophene behavior on the catalyst surface, that is responsible for the complex adsorption/desorption phenomena. It has been shown that the reaction is mainly affected by the strong adsorption of thiophene on the catalytic sites, with the critical step of the reaction represented by the saturation of the catalyst surface. In the experiment, the researchers used many compounds, for example, 3-Ethylthiophene (cas: 1795-01-3Category: benzothiophene).
3-Ethylthiophene (cas: 1795-01-3) belongs to benzothiophene derivatives. Benzothiophene is used as starting material for the synthesis of bioactive molecules. The core structure is a part of various pharmaceutical substances and natural products. It is found within the chemical structures of pharmaceutical drugs such as raloxifene, zileuton, and sertaconazole, and also BTCP.Category: benzothiophene
Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem