Month: February 2023

Incorporation of Fluorescent Dyes in Atmospheric Pressure Plasma Coatings for In-Line Monitoring of Coating Homogeneity was written by Somers, Wesley;Dubreuil, Marjorie F.;Neyts, Erik C.;Vangeneugden, Dirk;Bogaerts, Annemie. And the article was included in Plasma Processes and Polymers in 2014.Quality Control of 2,5-Bis(5-(tert-butyl)benzo[d]oxazol-2-yl)thiophene This article mentions the following:

This paper reports on the incorporation of three com. fluorescent dyes, i.e., rhodamine 6G, fluorescein, and fluorescent brightener 184, in plasma coatings, by utilizing a dielec. barrier discharge (DBD) reactor, and the subsequent monitoring of the coatings homogeneity based on the emitted fluorescent light. The plasma coatings are qual. characterized with fluorescence microscopy, UV-vis spectroscopy and profilometry for the determination of the coating thickness. The emitted fluorescent light of the coating correlates to the amount of dye per area, and deviations of these factors can hence be observed by monitoring the intensity of this light. This allows monitoring the homogeneity of the plasma coatings in a fast and simple way, without making major adjustments to the process. In the experiment, the researchers used many compounds, for example, 2,5-Bis(5-(tert-butyl)benzo[d]oxazol-2-yl)thiophene (cas: 7128-64-5Quality Control of 2,5-Bis(5-(tert-butyl)benzo[d]oxazol-2-yl)thiophene).

2,5-Bis(5-(tert-butyl)benzo[d]oxazol-2-yl)thiophene (cas: 7128-64-5) belongs to benzothiophene derivatives. Benzothiophene is relatively a stable molecule. The core structure is a part of various pharmaceutical substances and natural products. It is found within the chemical structures of pharmaceutical drugs such as raloxifene, zileuton, and sertaconazole, and also BTCP.Quality Control of 2,5-Bis(5-(tert-butyl)benzo[d]oxazol-2-yl)thiophene

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Direct synthesis of 1-naphthylamines enabled by 6-endo-dig cyclization strategy using copper catalysis was written by Ma, Peng;Wang, Jianhui;Liu, Guiyan. And the article was included in Applied Organometallic Chemistry in 2022.Category: benzothiophene This article mentions the following:

A facile approach for the synthesis of substituted 1-naphthylamines I [R¹ = Ph, 2-FC₆H₄, 3-ClC₆H₄, etc.; R² = H, 7-F, 6-Cl, etc.; R³ = H, CH₂CH=CH₂; R⁴ = Ph, Bn, Cy, etc.; R³ = R⁴ = Me; R³R⁴ = CH₂CH₂OCH₂CH₂] via three-component 6-endo-dig cyclization of terminal alkynes with 2-bromoaryl ketones, primary or secondary amines in water under Pd-free conditions was described. The Cu(I) catalytic system avoided a fundamental problem related to these substrates, which competitively evolve through 5-endo-dig cyclization pathways under metal catalysis. This unique performance unlocked a rapid access to a diverse 1-naphthylamines library that previously required longer synthetic routes. The synthetic potential of this method was further demonstrated by the gram-scale synthesis, and the mechanism study showed that the reaction experienced sequential halide exchange, imine-enamine tautomerization and 6-endo-dig cyclization. In the experiment, the researchers used many compounds, for example, 3-Ethynylthiophene (cas: 67237-53-0Category: benzothiophene).

3-Ethynylthiophene (cas: 67237-53-0) belongs to benzothiophene derivatives. Benzothiophene scaffolds are of great importance due to its increased presence in bioactive molecules. Its aromaticity makes it relatively stable, although as a heterocycle, it has reactive sites which allow for functionalization.Category: benzothiophene

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Synthesis and evaluation of dual wavelength fluorescent benzo[b]thiophene boronic acid derivatives for sugar sensing was written by Akay, Senol;Yang, Wenqian;Wang, Junfeng;Lin, Li;Wang, Binghe. And the article was included in Chemical Biology & Drug Design in 2007.HPLC of Formula: 1000160-75-7 This article mentions the following:

Cell surface glycoproteins have been known to play very important roles in various physiol. and pathol. processes. Small mol. compounds capable of carbohydrate recognition can be very useful for the development of sensing, diagnostic, and therapeutic agents. Along this line, the authors are interested in developing water-soluble fluorescent boronic acid compounds for carbohydrate recognition. As such, a series of benzo[b]thiophene boronic acid derivatives have been synthesized and their fluorescent properties analyzed at physiol. pH. Benzo[b]thiophene derivatives were a new type of fluorescent reporter compounds capable of dual fluorescent emission under physiol. pH conditions. Many of the synthesized Compounds showed unusual emission wavelength shifts upon binding of sugars. These boronic acids will be useful tools for building glycoprotein biosensors for biol. applications. In the experiment, the researchers used many compounds, for example, 2-(Benzo[b]thiophen-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (cas: 1000160-75-7HPLC of Formula: 1000160-75-7).

2-(Benzo[b]thiophen-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (cas: 1000160-75-7) belongs to benzothiophene derivatives. Benzothiophene is used as starting material for the synthesis of bioactive molecules. The core structure is a part of various pharmaceutical substances and natural products. It is found within the chemical structures of pharmaceutical drugs such as raloxifene, zileuton, and sertaconazole, and also BTCP.HPLC of Formula: 1000160-75-7

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

A Transmetalation Reaction Enables the Synthesis of [¹⁸F]5-Fluorouracil from [¹⁸F]Fluoride for Human PET Imaging was written by Hoover, Andrew J.;Lazari, Mark;Ren, Hong;Narayanam, Maruthi Kumar;Murphy, Jennifer M.;van Dam, R. Michael;Hooker, Jacob M.;Ritter, Tobias. And the article was included in Organometallics in 2016.Name: Benzo[b]thiophen-3-ylboronic acid This article mentions the following:

Translation of new ¹⁸F-fluorination reactions to produce radiotracers for human positron emission tomog. (PET) imaging is rare because the chem. must useful scope and the process for ¹⁸F-labeled tracer production must be robust and simple to execute. The application of transition metal mediators has enabled impactful ¹⁸F-fluorination methods, but to date none of these reactions were applied to produce a human-injectable PET tracer. The authors present chem. and process innovations that culminate in the 1st production from [¹⁸F]fluoride of human doses of [¹⁸F]5-fluorouracil, a PET tracer for cancer imaging in humans. The 1st preparation of Ni σ-aryl complexes by transmetalation from arylboronic acids or esters was developed, and enabled the synthesis of the [¹⁸F]5-fluorouracil precursor. Routine production of >10 mCi doses of [¹⁸F]5-fluorouracil was accomplished with a new instrument for azeotrope-free [¹⁸F]fluoride concentration in a process that leverages the tolerance of H₂O in Ni-mediated ¹⁸F-fluorination. In the experiment, the researchers used many compounds, for example, Benzo[b]thiophen-3-ylboronic acid (cas: 113893-08-6Name: Benzo[b]thiophen-3-ylboronic acid).

Benzo[b]thiophen-3-ylboronic acid (cas: 113893-08-6) belongs to benzothiophene derivatives. Benzothiophenes are valuable heterocycles that are widely used in medicines, agrochemicals, and materials science. It is found within the chemical structures of pharmaceutical drugs such as zileuton, raloxifene, and sertaconazole, and also BTCP.Name: Benzo[b]thiophen-3-ylboronic acid

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Gold-catalyzed intermolecular alkyne oxyarylation for C3 functionalization of benzothiophenes was written by Rist, Paige A.;Grainger, Richard S.;Davies, Paul W.. And the article was included in Organic Letters in 2021.Application of 1195-14-8 This article mentions the following:

C3-selective C-C bond formation on benzothiophenes is challenging, and few direct functionalization methods are available. A gold-catalyzed reaction of alkynes with benzothiophene S-oxides provides regioselective entry into C3-alkylated benzothiophenes with the C7-alkylated isomer as the minor product. This oxyarylation reaction works with alkyl and aryl alkynes and substituted and unsubstituted benzothiophenes. Mechanistic studies identify that sulfoxide inhibits the catalyst [DTBPAu(PhCN)]SbF₆, which also degrades and forms the unreactive complex [(DTBP)₂Au]SbF₆. In the experiment, the researchers used many compounds, for example, 2-Methylbenzo[b]thiophene (cas: 1195-14-8Application of 1195-14-8).

2-Methylbenzo[b]thiophene (cas: 1195-14-8) belongs to benzothiophene derivatives. Benzothiophene is a fused ring compound of thiophene ring and benzene ring, which is an important class of heterocycles with advantageous structures. It has been used as a raw material for the synthesis of biologically active structures and is found in pharmaceuticals such as leukotriene synthesis inhibitors and antifungals, as well as in many natural products.Application of 1195-14-8

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Impact of functionalization and co-additives on dioxazolone electrolyte additives was written by Gauthier, Roby;Hall, David S.;Lin, Katherine;Baltazar, Jazmin;Hynes, Toren;Dahn, J. R.. And the article was included in Journal of the Electrochemical Society in 2020.HPLC of Formula: 1072-53-3 This article mentions the following:

Finding new electrolyte additives could help create lithium-ion batteries with better performance at high voltage, allowing higher energy d. However, finding the perfect additive remains a tremendous challenge, since researchers still don’t understand how to predict their performance. A new group of dioxazolone electrolyte additives have been tested in lithium-ion batteries alone or in combination with well-known co-additives. The new additives consist of a 3-phenyl-1,4,2-dioxazol-5-one (PDO) parent structure with or without (methoxy, fluoro and nitro) functional groups on the para position of the Ph ring. It is found that PDO (no functional group) and p-(4-nitrophenyl)-1,4,2-dioxazol-5-one (pNDO) are the best performing dioxazolones overall and show promising results. In the experiment, the researchers used many compounds, for example, 1,3,2-Dioxathiolane 2,2-dioxide (cas: 1072-53-3HPLC of Formula: 1072-53-3).

1,3,2-Dioxathiolane 2,2-dioxide (cas: 1072-53-3) belongs to benzothiophene derivatives. Benzothiophene finds use in research as a starting material for the synthesis of larger, usually bioactive structures. It is found within the chemical structures of pharmaceutical drugs such as raloxifene, zileuton, and sertaconazole, and also BTCP.HPLC of Formula: 1072-53-3

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Simultaneous determination of fluorescent whitening agents (FWAs) and photoinitiators (PIs) in food packaging coated paper products by the UPLC-MS/MS method using ESI positive and negative switching modes was written by Wu, Zhijiang;Xu, Yansheng;Li, Mianchang;Guo, Xindong;Xian, Yanping;Dong, Hao. And the article was included in Analytical Methods in 2016.Application of 7128-64-5 This article mentions the following:

A sensitive ultra-high performance liquid chromatog. tandem mass spectrometry (UPLC-MS/MS) method was established for the simultaneous determination of fluorescent whitening agents (FWAs) and photoinitiators (PIs) in food packaging coated paper products. Samples were firstly soaked in water and then ultrasonically extracted by using methanol-trichloromethane. The extraction solution was subsequently separated by using a Phenomenex Luna C18 (2) chromatog. column (50 mm × 2.00 mm, 3 μm) using methanol-5 mmol L^-1 ammonium acetate as the mobile phase. The target analytes were ionized by the ESI pos. and neg. switching modes and detected using the multiple-reaction monitoring (MRM) mode. The method was validated for linearity and range, accuracy, precision and sensitivity. Under the optimized conditions, the calibration curves were linear over the selected concentration ranges of 10-1000 μg L^-1 and 0.5-50 μg L^-1 for four FWAs (FWA28, FWA85, FWA71 and FWA351) and the rest of the ten compounds, resp., with calculated coefficients of determination (R²) greater than 0.99. The instrument limit of quantitation (ILOQ) and the corresponding method limit of quantitation (MLOQ) of fourteen target analytes were in the range of 0.5-10 μg L^-1 and 6-125 μg kg^-1, resp. Recoveries were calculated at three levels of concentration spiked into neg. samples and the values were found between 79.2% and 115% with relative standard deviation (RSD) values of 3.2-12.3% for intra-day precision (n = 6) and 4.5-11.5% for inter-day precision (n = 5) 2.5-7.2%. The method was successfully applied to analyze twenty-five food packaging coated paper product samples and FWA184 and 4-MBP were detected in only two samples with the concentrations of 151 μg kg^-1 and 32 μg kg^-1, resp. In the experiment, the researchers used many compounds, for example, 2,5-Bis(5-(tert-butyl)benzo[d]oxazol-2-yl)thiophene (cas: 7128-64-5Application of 7128-64-5).

2,5-Bis(5-(tert-butyl)benzo[d]oxazol-2-yl)thiophene (cas: 7128-64-5) belongs to benzothiophene derivatives. Benzothiophene is a fused ring compound of thiophene ring and benzene ring, which is an important class of heterocycles with advantageous structures. Its aromaticity makes it relatively stable, although as a heterocycle, it has reactive sites which allow for functionalization.Application of 7128-64-5

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Shielding Effect of Nanomicelles: Stable and Catalytically Active Oxidizable Pd(0) Nanoparticle Catalyst Compatible for Cross-Couplings of Water-Sensitive Acid Chlorides in Water was written by Ansari, Tharique N.;Sharma, Sudripet;Hazra, Susanta;Jasinski, Jacek B.;Wilson, Andrew J.;Hicks, Frederick;Leahy, David K.;Handa, Sachin. And the article was included in JACS Au in 2021.Synthetic Route of C8H7BO2S This article mentions the following:

Under the shielding effect of nanomicelles, a sustainable micellar technol. for the design and convenient synthesis of ligand-free oxidizable ultrasmall Pd(0) nanoparticles (NPs) and their subsequent catalytic exploration for couplings of water-sensitive acid chlorides in water is reported. A proline-derived amphiphile, PS-750-M, plays a crucial role in stabilizing these NPs, preventing their aggregation and oxidation state changes. These NPs were characterized using ¹³C NMR (NMR), IR (IR), and surface-enhanced Raman scattering (SERS) spectroscopy to evaluate the carbonyl interactions of PS-750-M with Pd. High-resolution transmission electron microscopy (HRTEM) and energy-dispersive X-ray spectroscopy (EDX) studies were performed to reveal the morphol., particle size distribution, and chem. composition, whereas XPS measurements unveiled the oxidation state of the metal. In the cross-couplings of water-sensitive acid chlorides with boronic acids, the micelle’s shielding effect and boronic acids plays a vital role in preventing unwanted side reactions, including the hydrolysis of acid chlorides under basic pH. This approach is scalable and the applications are showcased in multigram scale reactions. In the experiment, the researchers used many compounds, for example, Benzo[b]thiophen-3-ylboronic acid (cas: 113893-08-6Synthetic Route of C8H7BO2S).

Benzo[b]thiophen-3-ylboronic acid (cas: 113893-08-6) belongs to benzothiophene derivatives. Benzothiophene scaffolds are of great importance due to its increased presence in bioactive molecules. It is found within the chemical structures of pharmaceutical drugs such as raloxifene, zileuton, and sertaconazole, and also BTCP.Synthetic Route of C8H7BO2S

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

The influence of hydrocarbon compositions of transformer oils on the electrostatic charging tendency was written by Yu, Hui-min;Ma, Shu-jie;Zhang, Qi;Zhang, Ling-jun. And the article was included in Runhuayou in 2010.Application In Synthesis of 3-Ethylthiophene This article mentions the following:

The results of studies on the electrostatic charging tendency of flowing transformer oils for OF-or OD- cooled super high voltage transformers were summarized. The influence of hydrocarbon compositions of transformer oils on the electrostatic charging tendency was studied in detail, in which the electrostatic charging tendency of naphthenic transformer oils with different aromatic hydrocarbons content, and the electrostatic charging tendency of different crude oil style transformer oils with the same aromatic hydrocarbons content were mostly investigated. The influences of the sulfide compounds, the nitride compounds, as well as poly-aromatics content on the electrostatic charging tendency were also studied. It was found that high poly-aromatics content in transformer oils should increase the electrostatic charging tendency of transformer oils. In the experiment, the researchers used many compounds, for example, 3-Ethylthiophene (cas: 1795-01-3Application In Synthesis of 3-Ethylthiophene).

3-Ethylthiophene (cas: 1795-01-3) belongs to benzothiophene derivatives. Benzothiophene is relatively a stable molecule. The core structure is a part of various pharmaceutical substances and natural products. It is found within the chemical structures of pharmaceutical drugs such as raloxifene, zileuton, and sertaconazole, and also BTCP.Application In Synthesis of 3-Ethylthiophene

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

A new kind of blue hybrid electroluminescent device was written by Wang, Junling;Li, Zhuan;Liu, Chunmei. And the article was included in Journal of Nanoscience and Nanotechnology in 2016.COA of Formula: C26H26N2O2S This article mentions the following:

Bright blue Electroluminescence come from an ITO/BBOT doped silica (6 × 10^-3 M) made by a sol-gel method/Al driven by AC with 500 Hz at different voltages and Gaussian anal. under 55 V showed that blue emission coincidenced with typical triple emission from BBOT. This kind of device take advantage of organics (BBOT) and inorganics (silica). Electroluminescence from a single-layered sandwiched device consisting of blue fluorescent dye 2,5-bis (5-tert-butyl-2-benzoxazolyl) thiophene (BBOT) doped silica made by sol-gel method was investigated. A number of concentrations of hybrid devices were prepared and the maximum concentration was 6 × 10^-3 M. Blue electroluminescent (EL) always occurred above a threshold field 8.57 × 10⁵ V/cm (30 V) at alternating voltage at 500 HZ. The luminance of the devices increased with the concentration of doped BBOT, but electroluminescence characteristics were different from a single mol.’s photoluminescence properties of triple peaks. When analyzing in detail direct-current electroluminescence devices of pure BBOT, a single peak centered at 2.82 eV appeared with the driven voltage increase, which is similar to the hybrid devices. Comparing Gaussian decomposition date between two kinds of devices, the triple peak characteristic of BBOT was consistent. It is inferred that BBOT contributed EL of the hybrid devices mainly and silica may account for a very small part. Meanwhile the thermal stability of matrix silica was measured by Thermal Gravity-Mass Spectroscopy (TG-MS). There is 12 percent weight loss from room temperature to 1000 °C and silica has about 95% transmittance. So the matric silica played an important role in thermal stability and optical stability for BBOT. In addition, this kind of blue electroluminescence device can take advantages of organic materials BBOT and inorganic materials silica. This is a promising way to enrich EL devices, especially enriching inorganic EL color at a low cost. In the experiment, the researchers used many compounds, for example, 2,5-Bis(5-(tert-butyl)benzo[d]oxazol-2-yl)thiophene (cas: 7128-64-5COA of Formula: C26H26N2O2S).

2,5-Bis(5-(tert-butyl)benzo[d]oxazol-2-yl)thiophene (cas: 7128-64-5) belongs to benzothiophene derivatives. Benzothiophene scaffolds are of great importance due to its increased presence in bioactive molecules. It is found within the chemical structures of pharmaceutical drugs such as raloxifene, zileuton, and sertaconazole, and also BTCP.COA of Formula: C26H26N2O2S

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem