Month: February 2023

Lattice-Matched Epitaxial Growth of Organic Heterostructures for Integrated Optoelectronic Application was written by Zhang, Yi;Liao, Qing;Wang, Xinguo;Yao, Jiannian;Fu, Hongbing. And the article was included in Angewandte Chemie, International Edition in 2017.Computed Properties of C26H26N2O2S This article mentions the following:

Development of nanowire photonics requires integration of different nanowire components into highly ordered functional heterostructures. A sequential self-assembly of binary mol. components into branched nanowire heterostructures (BNHs) via lattice-matched epitaxial growth is reported, in which the microribbon backbone of 2,5-Bis(5-tert-butyl-2-benzoxazolyl)thiophene (BBOT) functions as blue-emitting microlaser source to pump the nanowire branches of BODIPY. By constructing Au electrodes on both branch sides and measuring the photocurrent in them, the integration of an organic laser and a power meter in a single device is realized. This work provides a new insight into the integration of 1D organic nanostructures into BNHs for realizing organic multifunctional photonic devices. In the experiment, the researchers used many compounds, for example, 2,5-Bis(5-(tert-butyl)benzo[d]oxazol-2-yl)thiophene (cas: 7128-64-5Computed Properties of C26H26N2O2S).

2,5-Bis(5-(tert-butyl)benzo[d]oxazol-2-yl)thiophene (cas: 7128-64-5) belongs to benzothiophene derivatives. Benzothiophene is relatively a stable molecule. The core structure is a part of various pharmaceutical substances and natural products. Its aromaticity makes it relatively stable, although as a heterocycle, it has reactive sites which allow for functionalization.Computed Properties of C26H26N2O2S

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Prediction of Collision Cross Section Values: Application to Non-Intentionally Added Substance Identification in Food Contact Materials was written by Song, Xue-Chao;Dreolin, Nicola;Damiani, Tito;Canellas, Elena;Nerin, Cristina. And the article was included in Journal of Agricultural and Food Chemistry in 2022.Application In Synthesis of 2,5-Bis(5-(tert-butyl)benzo[d]oxazol-2-yl)thiophene This article mentions the following:

The synthetic chems. in food contact materials can migrate into food and endanger human health. In this study, the traveling wave collision cross section in nitrogen values of more than 400 chems. in food contact materials were exptl. derived by traveling wave ion mobility spectrometry. A support vector machine-based collision cross section (CCS) prediction model was developed based on CCS values of food contact chems. and a series of mol. descriptors. More than 92% of protonated and 81% of sodiated adducts showed a relative deviation below 5%. Median relative errors for protonated and sodiated mols. were 1.50 and 1.82%, resp. The model was then applied to the structural annotation of oligomers migrating from polyamide adhesives. The identification confidence of 11 oligomers was improved by the direct comparison of the exptl. data with the predicted CCS values. Finally, the challenges and opportunities of current machine-learning models on CCS prediction were also discussed. In the experiment, the researchers used many compounds, for example, 2,5-Bis(5-(tert-butyl)benzo[d]oxazol-2-yl)thiophene (cas: 7128-64-5Application In Synthesis of 2,5-Bis(5-(tert-butyl)benzo[d]oxazol-2-yl)thiophene).

2,5-Bis(5-(tert-butyl)benzo[d]oxazol-2-yl)thiophene (cas: 7128-64-5) belongs to benzothiophene derivatives. Functionalized benzothiophenes are important constructs found in molecules with wide ranging biological activity and in organic materials. Its aromaticity makes it relatively stable, although as a heterocycle, it has reactive sites which allow for functionalization.Application In Synthesis of 2,5-Bis(5-(tert-butyl)benzo[d]oxazol-2-yl)thiophene

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Copper-Catalyzed Direct Trifluoro- and Perfluoroalkylselenolations of Boronic Acids with a Shelf-Stable Family of Reagents was written by Glenadel, Quentin;Ghiazza, Clement;Tlili, Anis;Billard, Thierry. And the article was included in Advanced Synthesis & Catalysis in 2017.Formula: C8H7BO2S This article mentions the following:

Herein the copper-catalyzed direct perfluoroalkylselenolation of aryl- and vinylboronic acids is described for the first time. The key to success is the design of new shelf-stable perfluoroalkylselenolating reagents, namely perfluoroalkyl tolueneselenosulfonates. The reaction occurs at room temperature in the presence of com. available catalyst and ligand in catalytic quantities. In the experiment, the researchers used many compounds, for example, Benzo[b]thiophen-3-ylboronic acid (cas: 113893-08-6Formula: C8H7BO2S).

Benzo[b]thiophen-3-ylboronic acid (cas: 113893-08-6) belongs to benzothiophene derivatives. Benzothiophene is relatively a stable molecule. The electrophilic substitution of benzothiophene systems is much less regioselective than that of indoles. It is found within the chemical structures of pharmaceutical drugs such as raloxifene, zileuton, and sertaconazole, and also BTCP.Formula: C8H7BO2S

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Large Changes in Fluorescent Color and Intensity of Symmetrically Substituted Arylmaleimides Caused by Subtle Structure Modifications was written by Wang, Jingwei;Liu, Zhengde;Yang, Shuming;Lin, Youzhi;Lin, Zhenghuan;Ling, Qidan. And the article was included in Chemistry – A European Journal in 2018.Application In Synthesis of Benzo[b]thiophen-3-ylboronic acid This article mentions the following:

Herein we report on four diarylmaleimides based on 3- or 2-substituted benzothiophene (M3S or M2S) and benzofuran (M3O or M2O), which show very different emission properties: aggregation-caused quenching (ACQ), aggregation-induced emission (AIE), and dual-state strong emission (DSE) in both solution and solid states. Their emission color in the solid state can be adjusted from green-yellow into red. M2O displays strong red solid-state emission at 630 nm with a quantum yield of 46.3 %. Single-crystal X-ray diffraction anal. confirms that their large distinction in solid-state emission originates from their different packing structures: hydrogen-bonded organic frameworks (HOFs) for M3S, a staggered structure for M3O, J-aggregation for M2S, and weak H-aggregation for M2O. HOF of M3S and weak H-aggregation of M2O make them produce inverse-type piezochromic fluorescence: blueshifted “turn-on” and red shifted “turn-off” emission, resp. These results provide new insight in fluorescence manipulated by subtle structure modification. In the experiment, the researchers used many compounds, for example, Benzo[b]thiophen-3-ylboronic acid (cas: 113893-08-6Application In Synthesis of Benzo[b]thiophen-3-ylboronic acid).

Benzo[b]thiophen-3-ylboronic acid (cas: 113893-08-6) belongs to benzothiophene derivatives. Benzothiophene is relatively a stable molecule. The electrophilic substitution of benzothiophene systems is much less regioselective than that of indoles. It is also used in the manufacturing of dyes such as thioindigo.Application In Synthesis of Benzo[b]thiophen-3-ylboronic acid

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Synthesis and Biological Evaluation of a New Series of Pyrazolines as New Anticandidal Agents was written by Ozdemir, Ahmet;Altintop, Mehlika Dilek;Kaplancikli, Zafer Asim;Turan-Zitouni, Gulhan;Ciftci, Gulsen Akalin;Demirci, Fatih. And the article was included in Pharmaceutical Chemistry Journal in 2014.Product Details of 3988-77-0 This article mentions the following:

New pyrazoline derivatives bearing an oxadiazole moiety were synthesized via the reaction of 1-(chloroacetyl)-3-(2-furyl/thienyl)-5-aryl-2-pyrazolines with 5-substituted-1,3,4-oxadiazole-2(3H)-thiones in the presence of potassium carbonate. The pyrazolines were screened for their antifungal activity against various Candida species and compared with ketoconazole. Among these compounds, the most effective derivatives were evaluated for their cytotoxicity against NIH/3T3 cells. 2-({2-[5-(4-Bromophenyl)-3-(2-furyl)-4,5-dihydro-1H-pyrazol-1-yl]-2-oxoethyl}thio)-5-(2-cyclopentylethyl)-1,3,4-oxadiazole can be identified as the most potent antifungal agent against C. tropicalis due to its inhibitory effect on C. tropicalis and low toxicity to NIH/3T3 cells. In the experiment, the researchers used many compounds, for example, 3-Phenyl-1-(thiophen-2-yl)prop-2-en-1-one (cas: 3988-77-0Product Details of 3988-77-0).

3-Phenyl-1-(thiophen-2-yl)prop-2-en-1-one (cas: 3988-77-0) belongs to benzothiophene derivatives. Benzothiophene finds use in research as a starting material for the synthesis of larger, usually bioactive structures. It is also used in the manufacturing of dyes such as thioindigo.Product Details of 3988-77-0

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Sulfonylureas: a new class of cancer chemotherapeutic agents was written by Mohamadi, Fariborz;Spees, Michael M.;Grindey, Gerald B.. And the article was included in Journal of Medicinal Chemistry in 1992.Recommanded Product: 1795-01-3 This article mentions the following:

Sulofenur thiophene analogs, e.g. I (R = H, 5-Cl, 5-MeO, 4-Me, 5-Et; X = S, O, NH), were prepared from the corresponding heterocycle and ClSO₃H/NH₃/4-ClC₆H₄NCO or BuLi/SO₂/H₂NOSO₃H/4-ClC₆H₄NCO and tested against s.c. implanted 6C3HED lymphosarcoma. The spectrum of activity of I (R = MeO, X = S) in the HXGC3, VRC5, CX-1, and LX-1 cell lines is also presented. In the experiment, the researchers used many compounds, for example, 3-Ethylthiophene (cas: 1795-01-3Recommanded Product: 1795-01-3).

3-Ethylthiophene (cas: 1795-01-3) belongs to benzothiophene derivatives. Benzothiophene is used as starting material for the synthesis of bioactive molecules. The core structure is a part of various pharmaceutical substances and natural products. It is also used in the manufacturing of dyes such as thioindigo.Recommanded Product: 1795-01-3

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Ir(III)-Catalyzed Oxidative Annulation of Phenylglyoxylic Acids with Benzo[b]thiophenes was written by Wang, Zhigang;Yang, Mufan;Yang, Yudong. And the article was included in Organic Letters in 2018.SDS of cas: 5118-13-8 This article mentions the following:

An Ir(III)-catalyzed oxidative annulation of phenylglyoxylic acids with benzo[b]thiophenes for the construction of benzothieno[3,2-c][2]benzopyranones in one step is disclosed. Three C-H cleavages and C-C/C-O bond formations are involved in this reaction. This protocol features a relatively broad substrate scope, good functional group tolerance, good regioselectivities, mild reaction conditions, and scale-up synthesis. In the experiment, the researchers used many compounds, for example, 4-Bromobenzo[b]thiophene (cas: 5118-13-8SDS of cas: 5118-13-8).

4-Bromobenzo[b]thiophene (cas: 5118-13-8) belongs to benzothiophene derivatives. Benzothiophene finds use in research as a starting material for the synthesis of larger, usually bioactive structures. It is found within the chemical structures of pharmaceutical drugs such as raloxifene, zileuton, and sertaconazole, and also BTCP.SDS of cas: 5118-13-8

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Synthesis and Electrochemical Performance of Spheroid LiNi_1/3Co_1/3Mn_1/3O₂ in the Electrolyte Modified by Ethylene Sulfate and Methylene Methanedisulfonate was written by Cui, Yongli;Yang, Chao;Zhuang, Zhiheng;Wang, Mingzhen;Zhuang, Quanchao. And the article was included in Journal of Inorganic and Organometallic Polymers and Materials in 2018.Electric Literature of C2H4O4S This article mentions the following:

In this study, spheroid LiNi_1/3Co_1/3Mn_1/3O₂ (NCM111) cathode material were synthesized using LiOH with Ni_0.5Co_0.2Mn_0.3(OH)₂ precursor by a simple solid-state reaction, and characterized by X-ray diffraction and SEM. Electrochem. behavior of NCM111 was investigated by electrochem. impedance spectroscopy (EIS) combining with cyclic voltammogram (CV) and charge/discharge test in the 1 M LiPF₆-EC:EMC electrolyte with ethylene sulfate (DTD) and methylene methanedisulfonate (MMDS) additives either singly or in combination with high cutoff voltage of 3.0-4.5 V at room temperature of 25 °C or elevated temperature of 55 °C. It was found that DTD additive can increase the initial coulombic efficiency of NCM111, and the spheroid NCM111 can obtain the maximum initial discharge capacity of 177.81 mAh/g with the 2 wt% DTD, and keep 92.29% capacity retention after 80 cycles. The MMDS additives would decrease the initial discharge capacity of the NCM111, and enhance significantly long cycle life of the NCM111 with the capacity retention of 99.23% over 80 cycles at high voltage of 4.5 V. The additive combination 2 wt% DTD + 1 wt% MMDS was an optimal additive combination, demonstrating the 102.2% capacity retention over 80 cycles at room temperature and the 94.2% capacity retention over 70 cycles at elevated temperature of 55 °C. EIS results revealed that the additive blend of 2 wt% DTD + 1 wt% MMDS can drastically lower the kinetics impedance and suppress the growth rate of R_ct for the NCM111 electrode. In the experiment, the researchers used many compounds, for example, 1,3,2-Dioxathiolane 2,2-dioxide (cas: 1072-53-3Electric Literature of C2H4O4S).

1,3,2-Dioxathiolane 2,2-dioxide (cas: 1072-53-3) belongs to benzothiophene derivatives. Functionalized benzothiophenes are important constructs found in molecules with wide ranging biological activity and in organic materials. It is found within the chemical structures of pharmaceutical drugs such as raloxifene, zileuton, and sertaconazole, and also BTCP.Electric Literature of C2H4O4S

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Sustainable synthesis of pyrazoles using alcohols as the primary feedstock by an iron catalyzed tandem C-C and C-N coupling approach was written by Mondal, Rakesh;Guin, Amit Kumar;Pal, Subhasree;Mondal, Sucheta;Paul, Nanda D.. And the article was included in Organic Chemistry Frontiers in 2022.Category: benzothiophene This article mentions the following:

Authors report two new efficient iron-catalyzed synthetic strategies for multicomponent synthesis of tri-substituted pyrazoles using biomass-derived alcs. as the primary feedstock. A well-defined, bench stable, and easy to prepare Fe(II)-catalyst bearing a tridentate pincer 2-(phenyldiazenyl)-1,10-phenanthroline was used as the catalyst. A wide variety of tri-substituted pyrazoles were prepared via dehydrogenative coupling of alcs., and aryl hydrazines with secondary alcs. and alkynes, resp. These methods eliminate the potential use of any pre-functionalized starting materials, noble metal catalysts, oxidants, or additives producing various substituted pyrazoles in moderate to good isolated yields via sequential C-C and C-N bond formation. A series of control experiments and spectroscopic studies were performed to understand the plausible mechanism of these multicomponent reactions. In the experiment, the researchers used many compounds, for example, 2-Ethynylthiophene (cas: 4298-52-6Category: benzothiophene).

2-Ethynylthiophene (cas: 4298-52-6) belongs to benzothiophene derivatives. Benzothiophene scaffolds are of great importance due to its increased presence in bioactive molecules. It has been used as a raw material for the synthesis of biologically active structures and is found in pharmaceuticals such as leukotriene synthesis inhibitors and antifungals, as well as in many natural products.Category: benzothiophene

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Anti-biofilm Agents against Pseudomonas aeruginosa: A Structure-Activity Relationship Study of C-Glycosidic LecB Inhibitors was written by Sommer, Roman;Rox, Katharina;Wagner, Stefanie;Hauck, Dirk;Henrikus, Sarah S.;Newsad, Shelby;Arnold, Tatjana;Ryckmans, Thomas;Broenstrup, Mark;Imberty, Anne;Varrot, Annabelle;Hartmann, Rolf W.;Titz, Alexander. And the article was included in Journal of Medicinal Chemistry in 2019.Related Products of 69815-97-0 This article mentions the following:

Biofilm formation is a key mechanism of antimicrobial resistance. We have recently reported two classes of orally bioavailable C-glycosidic inhibitors of the Pseudomonas aeruginosa lectin LecB with antibiofilm activity. They proved efficient in target binding, were metabolically stable, nontoxic, selective, and potent in inhibiting formation of bacterial biofilm. Here, we designed and synthesized six new carboxamides and 24 new sulfonamides for a detailed structure-activity relationship for two clin. representative LecB variants. Sulfonamides generally showed higher inhibition compared to carboxamides, which was rationalized based on crystal structure analyses. Substitutions at the thiophenesulfonamide increased binding through extensive contacts with a lipophilic protein patch. These metabolically stable compounds showed a further increase in potency toward the target and in biofilm inhibition assays. In general, we established the structure-activity relationship for these promising antibiofilm agents and showed that modification of the sulfonamide residue bears future optimization potential. In the experiment, the researchers used many compounds, for example, 4-Methylthiophene-2-sulfonyl chloride (cas: 69815-97-0Related Products of 69815-97-0).

4-Methylthiophene-2-sulfonyl chloride (cas: 69815-97-0) belongs to benzothiophene derivatives. Benzothiophene scaffolds are of great importance due to its increased presence in bioactive molecules. It is found within the chemical structures of pharmaceutical drugs such as raloxifene, zileuton, sertaconazole, and also BTCP.Related Products of 69815-97-0

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem