Month: February 2023

Palladium-Catalyzed Tail-to-Tail Reductive Dimerization of Terminal Alkynes to 2,3-Dibranched Butadienes was written by Guo, Hongyu;Zhang, Sheng;Li, Yang;Yu, Xiaoqiang;Feng, Xiujuan;Yamamoto, Yoshinori;Bao, Ming. And the article was included in Angewandte Chemie, International Edition in 2022.Recommanded Product: 2-Ethynylthiophene This article mentions the following:

The palladium-catalyzed tail-to-tail reductive dimerization of terminal alkynes was described for the first time. Aromatic terminal alkynes bearing diverse and sensitive functional groups as well as aliphatic terminal alkynes are efficiently transformed to 2,3-dibranched butadienes H₂C(R)CC(R)CH₂ [R = Ph, 2-naphthyl, 2-thienyl, etc.]. The key to achieve a selective tail-to-tail reductive dimerization reaction is to control appropriately the acidity of the reaction solution, which is accomplished by a combined use of pivalic acid and para-toluenesulfonic acid. The tail-to-tail reductive dimerization reaction is proposed to proceed via a cationic alkenyl palladium intermediate under acidic conditions. In the experiment, the researchers used many compounds, for example, 2-Ethynylthiophene (cas: 4298-52-6Recommanded Product: 2-Ethynylthiophene).

2-Ethynylthiophene (cas: 4298-52-6) belongs to benzothiophene derivatives. Benzothiophene finds use in research as a starting material for the synthesis of larger, usually bioactive structures. Due to its aromaticity, thiophenes do not exhibit the same properties as conventional thioethers.Recommanded Product: 2-Ethynylthiophene

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Facile synthesis of pyrimidines via iminium catalyzed [4+2] reaction of α,β-unsaturated ketones with 1,3,5-triazines was written by Yang, Gongming;Chen, Lei;Wang, Jian;Jia, Qianfa;Wei, Jia;Du, Zhiyun. And the article was included in Tetrahedron Letters in 2015.Electric Literature of C13H10OS This article mentions the following:

[4+2] Cycloaddition of α,β-unsaturated ketones with 1,3,5-triazine via iminium catalysis has been developed. E.g., in presence of morpholine and K₂CO₃ in DMF, reaction of PhCH:CHCOMe with 1,3,5-triazine gave 79% pyrimidine derivative I. This method can prepare pyrimidines with high levels of regioselectivity and with good yields. In the experiment, the researchers used many compounds, for example, 3-Phenyl-1-(thiophen-2-yl)prop-2-en-1-one (cas: 3988-77-0Electric Literature of C13H10OS).

3-Phenyl-1-(thiophen-2-yl)prop-2-en-1-one (cas: 3988-77-0) belongs to benzothiophene derivatives. Functionalized benzothiophenes are important constructs found in molecules with wide ranging biological activity and in organic materials. The different substitution patterns in these heterocycles offer new opportunities for drug discovery and other applications in materials science.Electric Literature of C13H10OS

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Enantioselective Trost alkynylation with 2E,4E-5-bromo-2,4-pentadienal was written by Ervik, Karina;Vidar Hansen, Trond. And the article was included in Tetrahedron Letters in 2022.SDS of cas: 67237-53-0 This article mentions the following:

The synthetically useful aldehyde 2E,4E-5-bromo-2,4-pentadienal were subjected to the enantioselective Trost alkynylation protocol, yielding highly functionalized propargylic secondary alcs. in an enantioselective manner. In most cases, the isolated yields and enantiomeric excess of the products were modest to high, but several products were formed in both high yields and enantiomeric excess. In the experiment, the researchers used many compounds, for example, 3-Ethynylthiophene (cas: 67237-53-0SDS of cas: 67237-53-0).

3-Ethynylthiophene (cas: 67237-53-0) belongs to benzothiophene derivatives. Benzothiophene is used as starting material for the synthesis of bioactive molecules. The core structure is a part of various pharmaceutical substances and natural products. The different substitution patterns in these heterocycles offer new opportunities for drug discovery and other applications in materials science.SDS of cas: 67237-53-0

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Nitrogen-doped mesoporous carbon single crystal-based Ag nanoparticles for boosting mild CO₂ conversion with terminal alkynes was written by Zhang, Zhongzheng;Shi, Jialin;Zhu, Tianyang;Zhang, Lina;Wei, Wei. And the article was included in Journal of Colloid and Interface Science in 2022.SDS of cas: 67237-53-0 This article mentions the following:

Fabrication of efficient heterogeneous catalysts with high turnover frequency (TOF) is intriguing for rapid and scalable CO₂ conversion under mild conditions, but it still faces some challenges due to use of some bulky and irregular supports causing inaccessible inner pores and insufficient utilization of active sites. Herein, using a unique nitrogen-doped mesoporous single-crystal carbon (named IRFC) as a host for loading Ag nanoparticles for the first time, a series of Ag/IRFC catalysts with high TOF (8.7-22.3 h-1) were facilely prepared by a novel “impregnation and in-situ reduction” strategy. The neat morphol. and high porosity of IRFC with abundant N species, providing homogeneous surface, adequate space and anchoring sites for Ag immobilization, greatly facilitated the formation of highly-distributed ultrasmall Ag nanoparticles (2.3 nm). Meanwhile, smooth and short diffusion pathways were inherited from the ordered mesopores and small particle sizes of IRFC. Owing to these unparalleled structural features, the Ag/IRFC catalysts exhibited excellent catalytic activity, stability, and generality for mild CO₂ conversion even under diluted conditions. This work not only presents a novel catalyst for mild CO2 conversion, but also brings some inspirations to designing highly efficient catalysts using well-shaped supporting nanomaterials for direct utilization of low-concentration _CO2, such as flue gas. In the experiment, the researchers used many compounds, for example, 3-Ethynylthiophene (cas: 67237-53-0SDS of cas: 67237-53-0).

3-Ethynylthiophene (cas: 67237-53-0) belongs to benzothiophene derivatives. Benzothiophene scaffolds are of great importance due to its increased presence in bioactive molecules. The different substitution patterns in these heterocycles offer new opportunities for drug discovery and other applications in materials science.SDS of cas: 67237-53-0

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Multidimensional gas chromatography in combination with accurate mass, tandem mass spectrometry, and element-specific detection for identification of sulfur compounds in tobacco smoke was written by Ochiai, Nobuo;Mitsui, Kazuhisa;Sasamoto, Kikuo;Yoshimura, Yuta;David, Frank;Sandra, Pat. And the article was included in Journal of Chromatography A in 2014.Recommanded Product: 1795-01-3 This article mentions the following:

A method is developed for identification of sulfur compounds in tobacco smoke extract The method is based on large volume injection (LVI) of 10 μL of tobacco smoke extract followed by selectable one-dimensional (¹D) or two-dimensional (²D) gas chromatog. (GC) coupled to a hybrid quadrupole time-of-flight mass spectrometer (Q-TOF-MS) using electron ionization (EI) and pos. chem. ionization (PCI), with parallel sulfur chemiluminescence detection (SCD). In order to identify each individual sulfur compound, sequential heart-cuts of 28 sulfur fractions from ¹D GC to ²D GC were performed with the three MS detection modes (SCD/EI-TOF-MS, SCD/PCI-TOF-MS, and SCD/PCI-Q-TOF-MS). Thirty sulfur compounds were pos. identified by MS library search, linear retention indexes (LRI), mol. mass determination using PCI accurate mass spectra, formula calculation using EI and PCI accurate mass spectra, and structure elucidation using collision activated dissociation (CAD) of the protonated mol. Addnl., 11 mol. formulas were obtained for unknown sulfur compounds The determined values of the identified and unknown sulfur compounds were in the range of 10-740 ng mg total particulate matter (TPM) (RSD: 1.2-12%, n = 3). In the experiment, the researchers used many compounds, for example, 3-Ethylthiophene (cas: 1795-01-3Recommanded Product: 1795-01-3).

3-Ethylthiophene (cas: 1795-01-3) belongs to benzothiophene derivatives. Functionalized benzothiophenes are important constructs found in molecules with wide ranging biological activity and in organic materials. Its aromaticity makes it relatively stable, although as a heterocycle, it has reactive sites which allow for functionalization.Recommanded Product: 1795-01-3

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Chemoselective Hydrosilylation of the α,β-Site Double Bond in α,β- and α,β,γ,δ-Unsaturated Ketones Catalyzed by Macrosteric Borane Promoted by Hexafluoro-2-propanol was written by Zhan, Xiao-Yu;Zhang, Hua;Dong, Yu;Yang, Jian;He, Shuai;Shi, Zhi-Chuan;Tang, Lei;Wang, Ji-Yu. And the article was included in Journal of Organic Chemistry in 2020.Recommanded Product: 3988-77-0 This article mentions the following:

The B(C₆F₅)₃-catalyzed chemoselective hydrosilylation of α,β- and α,β,γ,δ-unsaturated ketones into the corresponding asym. ketones in mild reaction conditions is developed. Nearly 50 substrates including those bearing reducible functional groups such as alkynyl, alkenyl, cyano, and aromatic heterocycles are chemoselectively hydrosilylation in good to excellent yields. Isotope-labeling studies revealed that HFIP also served as hydrogen source in the process. In the experiment, the researchers used many compounds, for example, 3-Phenyl-1-(thiophen-2-yl)prop-2-en-1-one (cas: 3988-77-0Recommanded Product: 3988-77-0).

3-Phenyl-1-(thiophen-2-yl)prop-2-en-1-one (cas: 3988-77-0) belongs to benzothiophene derivatives. Benzothiophene finds use in research as a starting material for the synthesis of larger, usually bioactive structures. It is found within the chemical structures of pharmaceutical drugs such as raloxifene, zileuton, sertaconazole, and also BTCP.Recommanded Product: 3988-77-0

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

BBOT for applications in photovoltaic cells devices and organic diodes was written by Lewinska, G.;Puszynski, A.;Sanetra, J.. And the article was included in Synthetic Metals in 2015.Formula: C26H26N2O2S This article mentions the following:

In this work photovoltaic devices based on C. I. Fluorescent Brightener 184 preparing and features was presented. The brightener was a major component of the active layers of devices, in which was used the selected matrix. The study included are the results for the performed light emitting diodes based on architecture ITO/PEDOT: PSS/organic active layer/calcium/aluminum, we set the characteristics of the diodes. The main aim of the study was the use of BBOT for the construction of photovoltaic cells. We have made a number of devices bulk-heterojunction type cells based on architecture ITO/PEDOT:PSS/organic active layer/aluminum in various configurations concentrations and with different thicknesses of the active layers. We have analyzed the current-voltage characteristics of photovoltaic cells and determined parameters of photovoltaic cells. In the experiment, the researchers used many compounds, for example, 2,5-Bis(5-(tert-butyl)benzo[d]oxazol-2-yl)thiophene (cas: 7128-64-5Formula: C26H26N2O2S).

2,5-Bis(5-(tert-butyl)benzo[d]oxazol-2-yl)thiophene (cas: 7128-64-5) belongs to benzothiophene derivatives. Benzothiophene is relatively a stable molecule. The core structure is a part of various pharmaceutical substances and natural products. It is found within the chemical structures of pharmaceutical drugs such as raloxifene, zileuton, and sertaconazole, and also BTCP.Formula: C26H26N2O2S

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Identifying chondroprotective diet-derived bioactives and investigating their synergism was written by Davidson, Rose K.;Green, Jonathan;Gardner, Sarah;Bao, Yongping;Cassidy, Aedin;Clark, Ian M.. And the article was included in Scientific Reports in 2018.SDS of cas: 7128-64-5 This article mentions the following:

Osteoarthritis (OA) is a multifactorial disease and nutrition is a modifiable factor that may contribute to disease onset or progression. A detailed understanding of mechanisms through which diet-derived bioactive mols. function and interact in OA is needed. We profiled 96 diet-derived, mainly plant-based bioactives using an in vitro model in chondrocytes, selecting four candidates for further study. We aimed to determine synergistic interactions between bioactives that affected the expression of key genes in OA. Selected bioactives, sulforaphane, apigenin, isoliquiritigenin and luteolin, inhibited one or more interleukin-1-induced metalloproteinases implicated in OA (MMP1, MMP13, ADAMTS4, ADAMTS5). Isoliquiritigenin and luteolin showed reactive oxygen species scavenging activity in chondrocytes whereas sulforaphane had no effect and apigenin showed only a weak trend. Sulforaphane inhibited the IL-1/NFκB and Wnt3a/TCF/Lef pathways and increased TGFβ/Smad2/3 and BMP6/Smad1/5/8 signalling. Apigenin showed potent inhibition of the IL-1/NFκB and TGFβ/Smad2/3 pathways, whereas luteolin showed only weak inhibition of the IL-1/NFκB pathway. All four bioactives inhibited cytokine-induced aggrecan loss from cartilage tissue explants. The combination of sulforaphane and isoliquiritigenin was synergistic for inhibiting MMP13 gene expression in chondrocytes. In the experiment, the researchers used many compounds, for example, 2,5-Bis(5-(tert-butyl)benzo[d]oxazol-2-yl)thiophene (cas: 7128-64-5SDS of cas: 7128-64-5).

2,5-Bis(5-(tert-butyl)benzo[d]oxazol-2-yl)thiophene (cas: 7128-64-5) belongs to benzothiophene derivatives. Benzothiophene is relatively a stable molecule. The core structure is a part of various pharmaceutical substances and natural products. The different substitution patterns in these heterocycles offer new opportunities for drug discovery and other applications in materials science.SDS of cas: 7128-64-5

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Determination of thermal decomposition products of glucose by thermal analysis combined with FTIR and GC-MS was written by Liu, Chun-bo;Shen, Qin-peng;Yang, Guang-yu;Si, Xiao-xi;He, Pei;Wang, Kun-miao;Zhang, Hong-yu;Liu, Zhi-hua;Miao, Ming-ming. And the article was included in Lihua Jianyan, Huaxue Fence in 2014.SDS of cas: 1795-01-3 This article mentions the following:

A combination of thermal anal., FTIR and GC-MS was applied to the determination of thermal decomposition products of glucose. Under conditions of simultaneous thermal anal., the glucose sample was pyrolyzed in atm. of nitrogen and nitrogen oxygen gas mixture, and determined by IR scanning. GC-MS temperature was chosen with thermogravimetric curves and IR spectra. Products of pyrolysis were separated and identified by GC-MS. The exptl. results showed that, 44 compounds were detected in the thermal decomposition products of glucose at temperature of 220°C, 300°C, 350°C and 470°C; 76 compounds were detected in pyrolysis products of glucose at high temperature The anal. results were valuable for the application of glucose at different temperatures In the experiment, the researchers used many compounds, for example, 3-Ethylthiophene (cas: 1795-01-3SDS of cas: 1795-01-3).

3-Ethylthiophene (cas: 1795-01-3) belongs to benzothiophene derivatives. Benzothiophenes are valuable heterocycles that are widely used in medicines, agrochemicals, and materials science. Its aromaticity makes it relatively stable, although as a heterocycle, it has reactive sites which allow for functionalization.SDS of cas: 1795-01-3

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Bimetallic CoNi Nanoflowers for Catalytic Transfer Hydrogenation of Terminal Alkynes was written by Choudhary, Neha;Kumar, Viresh;Mobin, Shaikh M.. And the article was included in ChemistrySelect in 2022.Product Details of 4298-52-6 This article mentions the following:

The development of bimetallic and magnetic nanomaterials as a catalyst is highly desirable for organic transformations due to their recyclability for the sustainable future of chem. industries. Bimetallic CoNi nanoflowers were developed via the facile liquid-phase reduction method and were employed for the hydrogenation of terminal alkynes. The structural and morphol. studies were analyzed by X-ray diffraction, Field-Emission SEM, and High Resolution Transmission Electron Microscopy. The bimetallic CoNi nanoflower exhibited 100% conversion with ∼100% selectivity towards alkane products with recyclability up to six cycles. The transfer hydrogenation mechanism was proposed via diimide formation with Co(0)/Ni(0) state, confirmed by X-ray Photoemission Spectroscopy anal. In the experiment, the researchers used many compounds, for example, 2-Ethynylthiophene (cas: 4298-52-6Product Details of 4298-52-6).

2-Ethynylthiophene (cas: 4298-52-6) belongs to benzothiophene derivatives. Benzothiophene is a fused ring compound of thiophene ring and benzene ring, which is an important class of heterocycles with advantageous structures. It has been used as a raw material for the synthesis of biologically active structures and is found in pharmaceuticals such as leukotriene synthesis inhibitors and antifungals, as well as in many natural products.Product Details of 4298-52-6

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem