95-15-8,With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.95-15-8,Thianaphthene,as a common compound, the synthetic route is as follows.
Benzo[b]thiophene (10 g, 74.5 mmol) was dissolved in 250 ml of chloroform. The resulting solution was cooled down to 0C and bromine (7.87 ml, 152.8 mmol) was added. The mixture was stirred for 12h. The reaction mixture was poured into water and extracted with chloroform. The organic layer was separated, dried over anhydrous magnesium sulfate, and evaporated under reduced pressure to afford (3) as a white solid, yield 90%. 1H NMR (CDCl3, 400MHz) 7.76-7.74 (d, J=8.8Hz, 1H), 7.73-7.71 (d, J=8Hz, 1H), 7.45-7.41 (t, J=7.6Hz, 1H), 7.41-7.36 (t, J=8Hz, 1H) ppm.
The synthetic route of 95-15-8 has been constantly updated, and we look forward to future research findings.
Reference£º
Article; Jeon, Joon Ho; Lee, Nam-Jin; Lee, Ji-Hoon; Suh, Min Chul; Dyes and Pigments; vol. 111; (2014); p. 116 – 123;,
Benzothiophene – Wikipedia
Benzothiophene | C8H6S – PubChem