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Reference of 5394-13-8, Chemical Research Letters, May 2021. This type of reactivity has quickly become one of the cornerstones of modern catalysis . In a article, 5394-13-8, molcular formula is C8H5BrS, introducing its new discovery.

Protecting-group-independent cross-coupling of alpha-alkoxyalkyl- and alpha-acyloxyalkyltrifluoroborates with aryl and heteroaryl bromides is achieved through application of photoredox/nickel dual catalysis. Reactions occur under exceptionally mild conditions, with outstanding functional group compatibility and excellent observed tolerance of heteroarenes. This method offers expedient access to protected secondary benzylic alcohol motifs bearing benzyl, pivaloyl, and N,N-diisopropylcarbamoyl protecting groups.

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Reference:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

 

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Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction by binding to a specific portion of an enzyme and thus slowing or preventing a reaction from occurring. HPLC of Formula: C8H5BrS, C8H5BrS. A document type is Article, introducing its new discovery., HPLC of Formula: C8H5BrS

A number of nitrogen, sulfur or oxygen containing bis-heteroaromatic or bis-heterocyclic derivatives have been synthesized in good to excellent yields by homocoupling of the corresponding halogenated compounds in the presence of liganded (triphenylphosphine or 2,2′-bipyridine) nickel Complex Reducing Agents in THF or DME at 63 deg C.

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Benzothiophene – Wikipedia,
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Several 3-alkylaryl mimics of the enol intermediate in the reaction catalyzed by type II dehydroquinase were synthesized to investigate the effect on the inhibition potency of replacing the oxygen atom in the side chain by a carbon atom. The length and the rigidity of the spacer was also studied. The inhibitory properties of the reported compounds against type II dehydroquinase from Mycobacterium tuberculosis and Helicobacter pylori are also reported. The binding modes of these analogs in the active site of both enzymes were studied by molecular docking using GOLD 5.0 and dynamic simulations studies.

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Reference:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

 

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This is the end of this tutorial post, and I hope it has helped your research about 5394-13-8 .Application In Synthesis of 2-Bromobenzo[b]thiophene

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The deciphering of structure-property relationships is of high importance to rational design of functional molecules and to explore their potential applications. In this work, a series of silole derivatives substituted with benzo[b]thiophene (BT) at the 2,5-positions of the silole ring are synthesized and characterized. The experimental investigation reveals that the covalent bonding through the 2-position of BT (2-BT) with silole ring allows a better conjugation of the backbone than that achieved though the 5-position of BT (5-BT), and results in totally different emission behaviors. The silole derivatives with 5-BT groups are weakly fluorescent in solutions, but are induced to emit intensely in aggregates, presenting excellent aggregation-induced emission (AIE) characteristics. Those with 2-BT groups can fluoresce more strongly in solutions, but no obvious emission enhancements are found in aggregates, suggesting they are not AIE-active. Theoretical calculations disclose that the good conjugation lowers the rotational motions of BT groups, which enables the molecules to emit more efficiently in solutions. But the well-conjugated planar backbone is prone to form strong intermoelcular interactions in aggregates, which decreases the emission efficiency. Non-doped organic light-emitting diodes (OLEDs) are fabricated by using these siloles as emitters. AIE-active silole derivatives show much better elecroluminescence properties than those without the AIE characterisic, demonstrating the advantage of AIE-active emitters in OLED applications. Stay connected! Connecting benzo[b]thiophene with a silole ring through its 2- or 5-position furnishes silole derivatives with totally different photoluminescence and electroluminescence properties (see figure).

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Reference:
Benzothiophene – Wikipedia,
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New Advances in Chemical Research in 2021. Catalysts allow a reaction to proceed that has a lower activation energy than the uncatalyzed reaction. In heterogeneous catalysis, catalysts provide a surface to which reactants bind in a process of adsorption. Computed Properties of C8H5BrS. Introducing a new discovery about 5394-13-8, Name is 2-Bromobenzo[b]thiophene

Direct access to complex, enantiopure benzylamine architectures using a synergistic iridium photoredox/nickel cross-coupling dual catalysis strategy has been developed. New C(sp3)-C(sp2) bonds are forged starting from abundant and inexpensive natural amino acids.

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Reference:
Benzothiophene – Wikipedia,
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Reference of 5394-13-8, New research progress on 5394-13-8 in 2021. Redox catalysis has been broadly utilized in electrochemical synthesis due to its kinetic advantages over direct electrolysis. In a article, 5394-13-8, molcular formula is C8H5BrS, introducing its new discovery.

A mononuclear iron complex with 2-ethynylbenzo[b]thiophene C-coordinated to the (eta5-Cp*)(eta2-dppe)Fe (Cp* = pentamethylcyclopentadienyl, dppe = 1,2-diphenylphosphinoethane) framework (1) was prepared and characterized by 1H NMR, elemental analysis, and single crystal X-ray diffraction. The redox behavior of 1 was investigated by voltammetric methods and anodic spectroelectrochemistry in the UV?vis-NIR-IR region and compared with reference complexes including 2-ferrocenylbenzo[b]thiophene (2) and the 2-ethynylpyridine derivative of 1. The spin density distribution along the linear molecular backbone in 1+ was analyzed by DFT (BLYP35) and TDDFT calculations of a truncated model complex. The combined experimental and theoretical results revealed an important role of the ethynylene linker in determining the redox properties of this family of complexes and participation of the 2-ethynylbenzo[b]thiophene framework in the largely iron-based anodic electron transfer.

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Reference:
Benzothiophene – Wikipedia,
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The result showed that such a combination of chemo- and biocatalysis improved the catalytic yield more than two times compared with that of sole metal catalysis.I hope my blog about 5394-13-8 is helpful to your research.

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There is a demand for the development of a technique according to which sodium 2,2,6,6-tetramethylpiperidides (Na-TMPs) can be economically and efficiently synthesized through simple operations including a small number of steps under mild conditions in a short period of time. Also, there is a demand for the development of a technique according to which high-quality Na-TMPs that do not contain lithium or lithium compounds such as Li-TMP can be synthesized. The method for synthesizing sodium 2,2,6,6-tetramethylpiperidides includes a step of obtaining sodium 2,2,6,6-tetramethylpiperidides by reacting, in a reaction solvent, 2,2,6,6-tetramethylpiperidines with a dispersion product obtained by dispersing sodium in a dispersion solvent or an organosodium compound having an aromatic ring obtained through a reaction with a dispersion product obtained by dispersing sodium in a dispersion solvent.

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Reference:
Benzothiophene – Wikipedia,
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As with benzenoid donors, the electronic absorption spectra of the molecular complexes of simple or condensed sulfur or oxygen-containing five-membered heterocycles with TCNE (or DDQ) often show two charge-transfer bands.In many cases, the knowledge of the actual frequencies requires a technique of resolution.The results so obtained are correlated with the ionization potentials of donors on the one hand, and the refractivity of nonpolar solvents on the other hand.

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Reference:
Benzothiophene – Wikipedia,
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An efficient tandem elimination-cyclization-desulfitative arylation of 2-(gem-dibromovinyl)phenols(thiophenols) with sodium arylsulfinates has been developed. In the presence of TBAF-PdCl2-Cu(OAc)2-NEt 3, the reactions generated 2-arylbenzofurans(thiophenes) with good yields in one-pot under ligand-free conditions. The Royal Society of Chemistry 2013.

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Reference:
Benzothiophene – Wikipedia,
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Related Products of 5394-13-8, Chemistry is a science major with cience and engineering. The main research directions are chemical synthesis, preparation and modification of special coatings, and research on the structure and performance of functional materials. In a article, 5394-13-8, molcular formula is C8H5BrS, introducing its new discovery.

PURPOSE: A compound for an organic optoelectronic device is provided to efficiently inject or transfer electrons, and to offer high electrochemical stability, lifetime, and efficiency. CONSTITUTION: A compound is denoted by chemical formula 1. In the chemical formula 1: X^2 is N, B, or P; X^1 is O, S, S (O), S (O2), or NR’; R^1-R^9 are hydrogen, deuterium, a substituted or non-substituted C1-10 alkyl group, a substituted or non-substituted C6-30 aryl group, or a substituted or non-substituted C2-30 heteroaryl group; L^1 is a substituted or non-substituted C6-30 arylene group, or a substituted or non-substituted C2-30 heteroarylene group; and L^2 and L^3 are a single bond, a substituted or non-substituted C2-10 alkenylene group, a substituted or non-substituted C2-10 alkynylene group, a substituted or non-substituted C6-30 arylene group, or a substituted or non-substituted C2-30 heteroarylene group.

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Reference:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem