Category: benzothiophene

Ni, Penghui published the artcileA Three-Component Strategy for Benzoselenophene Synthesis under Metal-Free Conditions Using Selenium Powder, Recommanded Product: 3-Acetylthiophene, the main research area is three component indole acetophenone selenium; benzoselenophene preparation.

An efficient three-component benzoselenophenes formation has been developed from substituted indoles, acetophenones, and selenium powder under metal-free conditions. 2-Aryl indoles played an important role to promote benzoselenophene formation from acetophenone derivatives and selenium powder. One C-C and two C-Se bonds were selectively formed to provide 40 new benzoselenophenes in good yields.

Organic Letters published new progress about Acetophenones Role: RCT (Reactant), RACT (Reactant or Reagent). 1468-83-3 belongs to class benzothiophene, name is 3-Acetylthiophene, and the molecular formula is C6H6OS, Recommanded Product: 3-Acetylthiophene.

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Li, Wei published the artcileDesign of Ru(II)-NHC-Diamine Precatalysts Directed by Ligand Cooperation: Applications and Mechanistic Investigations for Asymmetric Hydrogenation, Name: 3-Acetylthiophene, the main research area is ruthenium heterocyclic carbene complex diamine precatalyst preparation; isocoumarin benzothiophene dioxide ketone enantioselective hydrogenation.

A modular synthesis of Ru(II)-NHC-diamine complexes from readily available chiral N-heterocyclic carbenes (NHCs) and chiral diamines is disclosed for the first time. The well-defined Ru(II)-NHC-diamine complexes show unique structure and coordination chem. including an unusual tridentate coordination effect of 1,2-diphenylethylenediamine. The isolated air-and moisture-stable Ru(II)-NHC-diamine complexes act as versatile precatalysts for the asym. hydrogenation of isocoumarins, benzothiophene 1,1-dioxides, and ketones. Moreover, based on the identification of reaction intermediates by stoichiometric reactions and NMR experiments, together with the DFT calculations, a possible catalytic cycle was proposed.

Journal of the American Chemical Society published new progress about Alcohols Role: SPN (Synthetic Preparation), PREP (Preparation). 1468-83-3 belongs to class benzothiophene, name is 3-Acetylthiophene, and the molecular formula is C6H6OS, Name: 3-Acetylthiophene.

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Xiao, Zihui published the artcileElectrochemical reduction of functionalized carbonyl compounds: enhanced reactivity over tailored nanoporous gold, Application In Synthesis of 1468-83-3, the main research area is reusable nanoporous gold catalyst preparation pore size carbonyl reduction; carbonyl compound diphenylsilane gold nanocatalyst electrochem reduction chemoselective; alc preparation.

The effect of the pore size of nanoporous gold (NPG) on electrochem. reduction of functionalized carbonyl compounds was investigated. NPG with a pore size of ∼30 nm significantly enhanced the reactivity with high chemoselectivity at a low-potential. Typically, p-nitrobenzaldehyde reduction demonstrated a high turnover frequency (TOF) up to 232000 h-1.

Nanoscale published new progress about Alcohols Role: SPN (Synthetic Preparation), PREP (Preparation). 1468-83-3 belongs to class benzothiophene, name is 3-Acetylthiophene, and the molecular formula is C6H6OS, Application In Synthesis of 1468-83-3.

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Ibrahim, Jessica Juweriah published the artcileEfficient Transfer Hydrogenation of Ketones Catalyzed by a Phosphine-Free Cobalt-NHC Complex, Synthetic Route of 1468-83-3, the main research area is ketone transfer hydrogenation cobalt NHC complex catalyst.

A simple phosphine-free cobalt-NHC pincer complex was synthesized and used for the transfer hydrogenation of ketones with 2-propanol as hydrogen donor. A broad range of ketones varying from aromatic, aliphatic and heterocyclic were effectively reduced to their corresponding alcs. in moderate to excellent yields with good tolerance of functional groups.

European Journal of Organic Chemistry published new progress about Alcohols Role: SPN (Synthetic Preparation), PREP (Preparation). 1468-83-3 belongs to class benzothiophene, name is 3-Acetylthiophene, and the molecular formula is C6H6OS, Synthetic Route of 1468-83-3.

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Duong, Uyen T. published the artcileReactivity of Carbenes in Aqueous Nanomicelles Containing Palladium Nanoparticles, Product Details of C6H6OS, the main research area is palladium nanoparticle aqueous nanomicelle nanocatalyst.

Palladium nanoparticles ligated with inexpensive triphenylphosphine and amphiphile PS-750-M are suitable for exploring the reactivity of carbenes in aqueous nanomicelles. Nanocatalyst is highly selective for metal-carbene migratory insertion, and micelle of PS-750-M shields the in situ generated carbene to prevent the dimerization. In addition to a broad substrate scope, the nanocatalyst is thoroughly characterized by NMR, SEM, high-resolution transmission electron microscopy, XPS, and thermogravimetric anal. The sustainability of the reaction system is demonstrated by the recyclability of both the catalyst and the micellar reaction medium at variable reaction scales. NMR and kinetics studies with the recycled catalyst revealed the retention of catalyst integrity. Control experiments including the dynamic light scattering study demonstrate the importance of PS-750-M.

ACS Catalysis published new progress about Aryl bromides Role: RCT (Reactant), RACT (Reactant or Reagent). 1468-83-3 belongs to class benzothiophene, name is 3-Acetylthiophene, and the molecular formula is C6H6OS, Product Details of C6H6OS.

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Chen, Dongdong published the artcileDomino synthetic strategy for tetrahydrothiophene derivatives from 2-acetylfuran/2-acetylthiophene, benzaldehydes, and sulfur powder, COA of Formula: C6H6OS, the main research area is tetrahydrothiophene preparation diastereoselective; acetylfuran benzaldehyde sulfur domino; acetylthiophene benzaldehyde sulfur domino.

A domino reaction from 2-acetylfuran/2-acetylthiophene, benzaldehydes and sulfur powder was developed to synthesize a series of tetrahydrothiophene derivatives I [R = H, 4-F, 4-Ph, etc.; X = O,S]. The reaction proceeded well to construct five new bonds and a tetrahydrothiophene ring by one-pot. A possible mechanism was proposed, involving a stepwise of Aldol/double Michael addition/internal SN2 cascaded reaction with sulfur powder acts as a source of sulfur. This method was characterized by mild reaction conditions, com. available starting materials and transition-metal-free.

Arabian Journal of Chemistry published new progress about Benzaldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 1468-83-3 belongs to class benzothiophene, name is 3-Acetylthiophene, and the molecular formula is C6H6OS, COA of Formula: C6H6OS.

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Li, Meiqi published the artcileRoute to Chiral Tetrahydrofuran Acetals via Pd-Catalyzed Asymmetric Allylic Cycloaddition of Vinyl Epoxides with β-Keto Enol Ethers, Safety of 3-Acetylthiophene, the main research area is THF acetal preparation enantioselective diastereoselective; vinyl epoxide keto enol ether asym allylic cycloaddition palladium.

An efficient method for the synthesis of functionalized chiral THF (THF) acetals via Pd-catalyzed asym. allylic cycloaddition has been developed. With a palladium catalyst coordinated by a chiral phosphine ligand, the protocol is enabled to combine readily available vinyl epoxides and β-keto enol ethers to produce THF acetals bearing three stereocenters in a broad substrate scope with uniformly high levels of enantio- and diastereoselectivity.

Organic Letters published new progress about Acetals Role: SPN (Synthetic Preparation), PREP (Preparation). 1468-83-3 belongs to class benzothiophene, name is 3-Acetylthiophene, and the molecular formula is C6H6OS, Safety of 3-Acetylthiophene.

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Dana, Suman published the artcileRuthenium(II)-Catalyzed Regioselective C-H Olefination of Aromatic Ketones and Amides with Allyl Sulfones, Recommanded Product: 3-Acetylthiophene, the main research area is aromatic ketone amide allyl sulfone olefination ruthenium catalyst.

A Ru(II)-catalyzed cross-dehydrogenative Heck-type olefination of arenes with allyl sulfones leveraging the assistance of weakly coordinating ketone and amide functional groups is reported. It features a distinct reactivity profile in comparison to other allylic congeners, where β-sulfonyl elimination was not detected. The ambiphilic nature of the allyl sulfone side chain has also been demonstrated through intramol. aza-Michael addition and aldol condensation. Mechanistic studies indicated the involvement of a reversible metalation step, where β-hydride elimination takes place selectively from the benzylic position.

Organic Letters published new progress about Alkenes Role: SPN (Synthetic Preparation), PREP (Preparation). 1468-83-3 belongs to class benzothiophene, name is 3-Acetylthiophene, and the molecular formula is C6H6OS, Recommanded Product: 3-Acetylthiophene.

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Majhi, Jadab published the artcileDynamic Kinetic Resolution of Alkenyl Cyanohydrins Derived from α,β-Unsaturated Aldehydes: Stereoselective Synthesis of E-Tetrasubstituted Olefins, Category: benzothiophene, the main research area is tetrasubstituted olefin stereoselective synthesis dynamic kinetic resolution alkenyl cyanohydrin; dynamic kinetic resolution alkenyl cyanohydrin unsaturated aldehyde.

A novel dynamic kinetic resolution (DKR) of tetrasubstituted alkenyl cyanohydrins prepared from the corresponding α,β-unsaturated aldehydes is described. The deprotonation of a geometrical mixture of tetrasubstituted alkenyl cyanohydrins with sodium diisopropylamide (NaDA) enables the equilibration of the E- and Z-olefins and the selective functionalization of former to selectively afford the E-adduct. Theor. studies indicate that the nature of the alkali metal cation is a critical component to lowering the barrier for interconversion between the two geometrical isomers, which provides the mechanistic basis for the DKR reaction. In addition, we demonstrate that the DKR reaction can be combined with a transition-metal-catalyzed allylic substitution to generate a stereodefined E-tetrasubstituted olefin and quaternary center in a single cross-coupling reaction.

Journal of the American Chemical Society published new progress about Alkenes Role: SPN (Synthetic Preparation), PREP (Preparation). 1468-83-3 belongs to class benzothiophene, name is 3-Acetylthiophene, and the molecular formula is C6H6OS, Category: benzothiophene.

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Ning, Yongquan published the artcileAg-Catalyzed Insertion of Alkynyl Carbenes into C-C Bonds of β-Ketocarbonyls: A Formal C(sp2) Insertion, Formula: C6H6OS, the main research area is allenyl diketone preparation; diketone insertion alkynyl carbene alkynyl nosyl hydrazone silver catalyst.

Herein, a silver-catalyzed alkynyl carbene insertion into β-ketocarbonyls I (R1 = R3 = Me, Et, Ph, 4-t-BuC6H4, 3-thienyl, etc., R2 = H; R1 = Ph, R2 = H, R3 = Me, 4-F3CC6H4; R1 = R3 = Me, R2 = Me, Et, PhCH2; etc.) using alkynyl N-nosylhydrazones II [R4 = cyclopropyl, Cl(CH2)3, Ph, 3-MeOC6H4, 3,5-Cl2C6H3, 2-naphthyl, 1-cyclohexen-1-yl, etc.; Ns = 2-nitrophenylsulfonyl] as alkynyl carbene precursors, which provides access to trisubstituted allenyl ketones III, is reported. This reaction represents the first example of an alkynyl carbene insertion into a C-C σ bond, affording products homologated with an sp2 carbon center. The products are useful substrates for further transformations. Exptl. investigations and theor. calculations suggest the reaction proceeds through a stepwise enol cyclopropanation/retro-aldol pathway.

Organic Letters published new progress about Allenes Role: SPN (Synthetic Preparation), PREP (Preparation). 1468-83-3 belongs to class benzothiophene, name is 3-Acetylthiophene, and the molecular formula is C6H6OS, Formula: C6H6OS.

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem