Category: benzothiophene

Hu, Wenkang published the artcileThe synthesis of methyl triazole-4-carboxylate gold(I) complex and application on allene synthesis and alkyne hydration, SDS of cas: 1468-83-3, the main research area is gold methyl triazolylcarboxylate complex preparation hydration catalyst; crystal structure gold methyl triazolylcarboxylate complex.

The Me 1H-1,2,3-triazole-4-carboxylate containing a strong electron-withdrawing group was developed and applied as a ligand for gold(I) cations. The resulting ester-triazole gold(I) complex was studied for its efficiency in catalyzing allene synthesis and alkyne hydration, in which an excellent catalytic efficiency was observed with low catalyst loadings.

Inorganic Chemistry Communications published new progress about Allenes Role: SPN (Synthetic Preparation), PREP (Preparation). 1468-83-3 belongs to class benzothiophene, name is 3-Acetylthiophene, and the molecular formula is C6H6OS, SDS of cas: 1468-83-3.

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Chen, Shanping published the artcileThree-Component Cascade Synthesis of Carbazoles through [1s,6s] Sigmatropic Shift under Metal-Free Conditions, Product Details of C6H6OS, the main research area is carbazole derivative preparation; indole arylketone methacrylate three component reaction sigmatropic shift.

A novel method was developed for the synthesis of substituted carbazoles from com. available starting materials under metal-free conditions. This strategy involves a [1s,6s] sigmatropic shift step and introduces an electron-withdrawing ester substituent at the C2 position of the carbazole ring. The present protocol afforded the desired carbazole derivatives with good regioselectivity and well functional group tolerance. DFT calculations were carried out to support the reaction pathway.

Journal of Organic Chemistry published new progress about Aryl ketones Role: RCT (Reactant), RACT (Reactant or Reagent). 1468-83-3 belongs to class benzothiophene, name is 3-Acetylthiophene, and the molecular formula is C6H6OS, Product Details of C6H6OS.

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Chen, Jing published the artcileSelectfluor-promoted Synthesis of 2,4- and 2,6-Diarylpyridines Through Annulation of Aromatic Ketones with an Ammonium Source in DMF, Synthetic Route of 1468-83-3, the main research area is diarylpyridine preparation regioselective; aromatic ketone ammonium acetate DMF condensation cyclization Selectfluor.

An efficient one-pot four-component condensation and cyclization of ketones with DMF and ammonium acetate for the synthesis of 2,4-diarylsubstituted pyridines promoted by Selectfluor has been achieved. Sym. pyridines were obtained selectively when non-Me ketones were used as the starting materials. Two C-C and C-N bonds are formed during the oxidative cyclization process.

ChemistrySelect published new progress about Aryl ketones Role: RCT (Reactant), RACT (Reactant or Reagent). 1468-83-3 belongs to class benzothiophene, name is 3-Acetylthiophene, and the molecular formula is C6H6OS, Synthetic Route of 1468-83-3.

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Cai, Qun published the artcileI2-promoted tandem cyclization to synthesize polysubstituted pyrano[3,2-c]chromene-2,5-diones, Recommanded Product: 3-Acetylthiophene, the main research area is aryl ethanone hydroxycoumarin iodine tandem iodination Kornblum oxidation heterocyclization; hydroxybenzoyl aroyl pyranochromene dione preparation.

An efficient and convenient method for the synthesis of various substituted pyrano[3,2-c]chromene-2,5-diones was developed via the I2-promoted tandem cyclization of com. available aryl Me ketones and 4-hydroxycoumarins. Preliminary mechanism studies indicated that the reaction involved a consecutive iodination/Kornblum oxidation/annulation process. HI produced in the I2-DMSO system acted as an important promoter, accelerating the annulation protocol.

Tetrahedron published new progress about Aryl ketones Role: RCT (Reactant), RACT (Reactant or Reagent). 1468-83-3 belongs to class benzothiophene, name is 3-Acetylthiophene, and the molecular formula is C6H6OS, Recommanded Product: 3-Acetylthiophene.

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Zhang, Bing published the artcileRhodium-Catalyzed Regiodivergent Synthesis of Alkylboronates via Deoxygenative Hydroboration of Aryl Ketones: Mechanism and Origin of Selectivities, Recommanded Product: 3-Acetylthiophene, the main research area is rhodium catalyzed regiodivergent regioselective hydroboration aryl ketone; branched alkylboronate triboronate preparation; mol structure calculation rhodium catalyzed regioselective hydroboration aryl ketone.

Here, authors report an efficient rhodium-catalyzed deoxygenative borylation of ketones to synthesize alkylboronates, in which the regioselectivity can be switched by the choice of the ligand. The linear alkylboronates were obtained exclusively in the presence of P(nBu)3, and PPh2Me favored the formation of branched alkylboronates. The protocol also allows access to 1,1,2-triboronates from the readily available ketones. Mechanistic studies suggest that this Rh-catalyzed deoxygenative borylation of ketones goes through an alkene intermediate, which undergoes regiodivergent hydroboration to afford linear and branched alkylboronates. The different steric effects of PPh2Me and P(nBu)3 were responsible for product selectivity by d. functional theory calculations The alkene intermediate can alternatively undergo sequential dehydrogenative borylation and hydroboration to deliver the triboronates.

ACS Catalysis published new progress about Aryl ketones Role: RCT (Reactant), RACT (Reactant or Reagent). 1468-83-3 belongs to class benzothiophene, name is 3-Acetylthiophene, and the molecular formula is C6H6OS, Recommanded Product: 3-Acetylthiophene.

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Wu, Xin-Xing published the artcileSelective synthesis of acylated caprolactam via sequential Michael addition/palladium-catalyzed alpha-arylation of ketones, Application In Synthesis of 1468-83-3, the main research area is acylated caprolactam preparation diastereoselective; methyl ketone acrylamide Michael addition alpha arylation palladium catalyst.

A formal [6 + 1] annulation reaction through sequential Michael addition/palladium-catalyzed alpha-arylation of ketones has been developed. This approach provides an efficient route enabling rapid access to diverse acylated caprolactams by the double C-C bond formation of the same site from Me ketones. In addition, the reaction features a broad substrate scope, good functional group tolerance, easy scale-up of reaction and useful transformations of the products.

Organic Chemistry Frontiers published new progress about Acrylamides Role: RCT (Reactant), RACT (Reactant or Reagent). 1468-83-3 belongs to class benzothiophene, name is 3-Acetylthiophene, and the molecular formula is C6H6OS, Application In Synthesis of 1468-83-3.

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Otvos, Sandor B. published the artcileBismuth(III)-Catalyzed Hydration of Terminal Alkynes: Sustainable Synthesis of Methyl Ketones in Batch and Flow, Name: 3-Acetylthiophene, the main research area is methyl ketone batch preparation bismuth catalyst alkyne hydration.

Environmentally benign synthesis of Me ketones is demonstrated via unprecedented bismuth(III)-catalyzed activation and Markovnikov-type hydration of terminal acetylenes. Besides a batch process operating under reasonably mild conditions, a chem. intensified high-temperature continuous-flow methodol. also was developed using a coil reactor. The preparative capabilities of the flow process were demonstrated with multigram-scale alkyne hydrations. The methods presented rely on readily available bismuth(III) salts as “”green”” catalysts and exhibit less environmental concerns than earlier methods.

ACS Sustainable Chemistry & Engineering published new progress about Alkynes, α- Role: RCT (Reactant), RACT (Reactant or Reagent). 1468-83-3 belongs to class benzothiophene, name is 3-Acetylthiophene, and the molecular formula is C6H6OS, Name: 3-Acetylthiophene.

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Laha, Joydev K. published the artcileMinisci aroylation of N-heterocycles using choline persulfate in water under mild conditions, Safety of 3-Acetylthiophene, the main research area is acyl isoquinoline indole preparation green chem choline persulfate mediated; isoquinoline indoel arylglyoxylic acid Minisci aroylation choline persulfate.

Metal persulfate mediated thermal oxidative organic transformations invariably require a higher temperature and frequently use an organic solvent. The objective of this work was to develop persulfate mediated oxidative transformations that can be performed nearly at room temperature using water as a solvent. This report describes modified Minisci aroylation of isoquinolines with arylglyoxylic acids using choline persulfate and its pre-composition (choline acetate and K2S2O8) in water at 40°C. A few other nitrogen heterocycles were also utilized affording various aroylated products in good to excellent yields. Unlike metal persulfate that could produce metal salt byproducts, a key feature of the chem. reported herein includes the use of environmentally benign choline persulfate containing biodegradable choline as a counter-cation, the Minisci reaction demonstrated at 40°C in water as the only solvent, and unconventional activation of persulfate.

New Journal of Chemistry published new progress about Aryl ketones Role: SPN (Synthetic Preparation), PREP (Preparation). 1468-83-3 belongs to class benzothiophene, name is 3-Acetylthiophene, and the molecular formula is C6H6OS, Safety of 3-Acetylthiophene.

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Vigneswaran, Vipulan published the artcileBeta-amino phosphine Mn catalysts for 1,4-transfer hydrogenation of chalcones and allylic alcohol isomerization, Safety of 3-Acetylthiophene, the main research area is amino phosphine Mn catalyst preparation transfer hydrogenation chalcone isomerization; transfer hydrogenation chalcone allylic alc isomerization.

Mn complexes with amino acid derived PN ligands were used in the catalytic transfer hydrogenation (TH) of ketone and chalcone substrates in 2-propanol with mild heating. Moreover, chalcones are reduced selectively to the saturated ketone at short times and can be fully converted to the alc. when reactions are prolonged. The mechanism of chalcone reduction was briefly considered. Allylic alcs. are not reactive in 2-propanol, but quant. isomerization occurs in toluene. Thus, we suspect that the allylic alcs. are dehydrogenated and the resulting ketone is formed through a direct 1,4-hydrogenation of the chalcone. Finally, several other related ligands that have been used in Mn-based TH reactions were explored to test the viability of ligand design in favoring chemoselectivity. The β-amino phosphine ligands proved most effective in this regard. Mn complexes with amino acid-derived PN ligands were used to enact catalytic transfer hydrogenation (TH) of ketone and chalcone substrates in 2-proponal with mild heating. Moreover, chalcones are reduced selectively to the saturated ketone at short times and can be fully converted to the alc. under prolonged reactions. The mechanism of chalcone reduction was briefly considered. Allylic alcs. are not reactive in 2-proponal, but quant. isomerization occurs in toluene. Thus, we suspect that the allylic alcs. are dehydrogenated and the resulting ketone is formed through a direct 1,4-hydrogenation of the chalcone. Finally, several other related ligands that have been used in Mn-based TH reactions were explored to test the viability of ligand design in favoring chemoselectivity. The beta-amino phosphine ligands proved most effective in this regard.

Organometallics published new progress about Allylic alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 1468-83-3 belongs to class benzothiophene, name is 3-Acetylthiophene, and the molecular formula is C6H6OS, Safety of 3-Acetylthiophene.

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Cao, Fei published the artcileThe preparation of a Co@C3N4 catalyst and applications in the synthesis of quinolines from 2-aminobenzyl alcohols with ketones, Category: benzothiophene, the main research area is cobalt doped carbon nitride catalyst quinoline synthesis aminobenzenemethanol ketone.

An unsym. diphenylphosphino-pyridinyl-triazole ligand was synthesized and characterized through IR, NMR and MS and the corresponding earth-abundant metal complex (cobalt) was prepared Considering energy consumption and environmental friendliness, it is necessary to turn this diphenylphosphino-pyridinyl-triazole cobalt complex into a recyclable catalyst, which could easily be reused. Therefore, a heterogeneous catalyst was synthesized through Co-doping of C3N4, and the Co-nanoparticles on C3N4 revealed high catalytic activity for the synthesis of quinolines with good recovery performance.

New Journal of Chemistry published new progress about Aralkyl alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 1468-83-3 belongs to class benzothiophene, name is 3-Acetylthiophene, and the molecular formula is C6H6OS, Category: benzothiophene.

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem