Category: benzothiophene

Kraft, Ulrike; Anthony, John E.; Ripaud, Emilie; Loth, Marsha A.; Weber, Edwin; Klauk, Hagen published an article on February 10 ,2015. The article was titled 《Low-Voltage Organic Transistors Based on Tetraceno[2,3-b]thiophene: Contact Resistance and Air Stability》, and you may find the article in Chemistry of Materials.Quality Control of 2-(Thiophen-3-yl)-1,3-dioxolane The information in the text is summarized as follows:

The small-mol. organic semiconductor tetraceno[2,3-b]thiophene was synthesized through an environmentally friendly synthetic route, using NaBH4, rather than Al/HgCl2, for the reduction of the quinone. Low-voltage organic thin-film transistors (TFTs) were fabricated using tetraceno[2,3-b]thiophene and, for comparison, pentacene and anthradithiophene as the semiconductor. The tetraceno[2,3-b]thiophene TFTs have an effective field-effect mobility as large as 0.55 cm2 V-1 s-1 and a subthreshold swing of 0.13 V/decade. The contact resistance of the tetraceno[2,3-b]thiophene TFTs is substantially smaller than that of the anthradithiophene TFTs and similar to that of the pentacene TFTs. The long-term air stability of TFTs based on all three semiconductors was monitored over a period of 12 mo. The initial charge-carrier mobility of the tetraceno[2,3-b]thiophene TFTs is ∼50% smaller than that of the pentacene TFTs, but as a result of the greater ionization potential and better air stability induced by the terminal thiophene ring condensed at the thiophene-b-bond, the tetraceno[2,3-b]thiophene TFTs outperform the pentacene TFTs after continuous exposure to ambient air for just 3 mo. In the experimental materials used by the author, we found 2-(Thiophen-3-yl)-1,3-dioxolane(cas: 13250-82-3Quality Control of 2-(Thiophen-3-yl)-1,3-dioxolane)

2-(Thiophen-3-yl)-1,3-dioxolane(cas: 13250-82-3) is one of dioxolane. 1,3-Dioxolane derivatives are recognized as important motifs for the construction of numerous pharmacologically active molecules as antiviral, antifungal, anti-HIV, and adrenoreceptor antagonists.Quality Control of 2-(Thiophen-3-yl)-1,3-dioxolane

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Quality Control of 1-Thiophen-2-yl-ethanoneIn 2019 ,《Metal-Ligand Cooperative Approach To Achieve Dehydrogenative Functionalization of Alcohols to Quinolines and Quinazolin-4(3H)-ones under Mild Aerobic Conditions》 appeared in Journal of Organic Chemistry. The author of the article were Das, Siuli; Sinha, Suman; Samanta, Deepannita; Mondal, Rakesh; Chakraborty, Gargi; Brandao, Paula; Paul, Nanda D.. The article conveys some information:

A simple metal-ligand cooperative approach for the dehydrogenative functionalization of alcs. to various substituted quinolines and quinazolin-4(3H)-ones under relatively mild reaction conditions (≤90 °C) is reported. Simple and easy-to-prepare air-stable Cu(II) complexes featuring redox-active azo-aromatic scaffolds, 2-arylazo-(1,10-phenanthroline) (L1,2), are used as catalyst. A wide variety of substituted quinolines and quinazolin-4(3H)-ones were synthesized in moderate to good isolated yields via dehydrogenative coupling reactions of various inexpensive and easily available starting materials under aerobic conditions. A few control experiments and deuterium labeling studies were carried out to understand the mechanism of the dehydrogenative coupling reactions, which indicate that both copper and the coordinated azo-aromatic ligand participate in a cooperative manner during the catalytic cycle. In the experiment, the researchers used 1-Thiophen-2-yl-ethanone(cas: 88-15-3Quality Control of 1-Thiophen-2-yl-ethanone)

1-Thiophen-2-yl-ethanone(cas: 88-15-3) belongs to thiophenes. Reflecting their high stabilities, thiophenes arise from many reactions involving sulfur sources and hydrocarbons, especially unsaturated ones. Thiophenes are classically prepared by the reaction of 1,4-diketones, diesters, or dicarboxylates with sulfidizing reagents such as P4S10 such as in the Paal-Knorr thiophene synthesis. Quality Control of 1-Thiophen-2-yl-ethanone

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

《Visible-light mediated facile dithiane deprotection under metal free conditions》 was published in Tetrahedron Letters in 2020. These research results belong to Dharpure, Pankaj D.; Bhowmick, Anindita; Warghude, Prakash K.; Bhat, Ramakrishna G.. Recommanded Product: 88-15-3 The article mentions the following:

Visible light mediated facile and selective dithiane deprotection under metal free conditions is developed. Eosin Y (1 mol%) proved to be an effective catalyst for the dithiane deprotection under the ambient photoredox conditions. The standard household compact fluorescent light source (CFL bulb) proved to be effective under open-air conditions in aqueous acetonitrile at room temperature The protocol that exhibits a broad substrate scope and functional group tolerance has been shown to expand to a range of transformations for the electron-rich and -deficient thioacetals and thioketals. The synthetic utility of this protocol has also been demonstrated by gram-scale application. The experimental part of the paper was very detailed, including the reaction process of 1-Thiophen-2-yl-ethanone(cas: 88-15-3Recommanded Product: 88-15-3)

1-Thiophen-2-yl-ethanone(cas: 88-15-3) belongs to thiophenes. Specialized thiophenes can be synthesized similarly using Lawesson’s reagent as the sulfidizing agent, or via the Gewald reaction, which involves the condensation of two esters in the presence of elemental sulfur. Another method is the Volhard–Erdmann cyclization. Recommanded Product: 88-15-3

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Reference of 1-Thiophen-2-yl-ethanoneIn 2020 ,《Rapid Access to Borylated Thiophenes Enabled by Visible Light》 was published in Organic Letters. The article was written by Herrera-Luna, Jorge C.; Sampedro, Diego; Jimenez, M. Consuelo; Perez-Ruiz, Raul. The article contains the following contents:

B-containing thiophenes are important entities in organic/medicinal chem. as well as in material science. In this Letter, a novel, straightforward, and fast procedure for their production employing visible light as an energy source at room temperature and ambient pressure is reported. All substrates are com. available, and the process does not require the use of any external photocatalyst. In addition to this study using 1-Thiophen-2-yl-ethanone, there are many other studies that have used 1-Thiophen-2-yl-ethanone(cas: 88-15-3Reference of 1-Thiophen-2-yl-ethanone) was used in this study.

1-Thiophen-2-yl-ethanone(cas: 88-15-3) belongs to thiophenes. Reflecting their high stabilities, thiophenes arise from many reactions involving sulfur sources and hydrocarbons, especially unsaturated ones. Thiophenes are classically prepared by the reaction of 1,4-diketones, diesters, or dicarboxylates with sulfidizing reagents such as P4S10 such as in the Paal-Knorr thiophene synthesis. Reference of 1-Thiophen-2-yl-ethanone

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Su, Biyun; Han, Qiaoqiao; Li, Xiaoteng; Hou, Yifan; Wu, Jindi; Wang, Li; Ding, Liqin published an article in 2021. The article was titled 《Synthesis, isomerization, and DFT studies of five-membered heterocyclic ketoximes》, and you may find the article in Journal of Chemical Research.Synthetic Route of C6H6OS The information in the text is summarized as follows:

A homologous series of five-membered heterocyclic ketoximes was synthesized by condensation reactions of 2-acetylpyrrole, 2-acetylthiophene, and 2-acetylfuran with hydroxylamine hydrochloride. These compounds were fully characterized by X-ray single-crystal diffraction, elemental anal., 1H NMR, IR, UV-Vis, and fluorescence spectra. Interesting isomerization phenomena are observed for these heterocyclic ketoximes by different characterization methods. By means of 1H NMR and X-ray single-crystal diffraction, it was found that 2-acetylpyrrole oxime exists as the Z-type geometric isomer, 2-acetylfuran oxime exists as the E-isomer, while 2-acetylthiophene oxime was identified as a mixture of Z- and E-isomers. To study the above phenomena further, quantum chem. calculations of total energy, dipole moment, EHOMO, ELUMO, and other parameters of each heterocyclic ketoxime were carried out by D. functional theory (DFT). The theor. calculations were in good accordance with the exptl. spectroscopic results. After reading the article, we found that the author used 1-Thiophen-2-yl-ethanone(cas: 88-15-3Synthetic Route of C6H6OS)

1-Thiophen-2-yl-ethanone(cas: 88-15-3) belongs to thiophenes. Specialized thiophenes can be synthesized similarly using Lawesson’s reagent as the sulfidizing agent, or via the Gewald reaction, which involves the condensation of two esters in the presence of elemental sulfur. Another method is the Volhard–Erdmann cyclization. Synthetic Route of C6H6OS

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

《Accelerated Metal-Free Hydration of Alkynes within Milliseconds in Microdroplets》 was written by Zheng, Boyu; Jin, Xiaoxiao; Liu, Jinhua; Cheng, Heyong. Reference of 1-Thiophen-2-yl-ethanone And the article was included in ACS Sustainable Chemistry & Engineering in 2021. The article conveys some information:

Conversion of alkynes into ketones by hydration is one of the most fundamental organic addition reactions. Traditional methods for alkyne hydration suffer from usage of toxic and costly metals, excessive acids, harsh conditions, and long reaction times, bringing about an urgent desire to explore more efficient and green protocols to complete this transformation. A metal-free efficient protocol for the accelerated hydration of alkynes in microdroplets was successfully developed in this work to overcome these drawbacks. The hydration process was finished under room temperature using only 18 mol % sulfuric acid as the catalyst and acetonitrile as the solvent. Complete conversions were feasible on the low millisecond time scale in microdroplets for a wide range of alkynes bearing functional groups, including electron-withdrawing groups and electron-donating groups. This is in sharp contrast to trace amounts of ketones or none in 20 min in bulk phase. Compared to the bulk reaction under the same conditions, the reactions in microdroplets are accelerated by 4 to 5 orders of magnitude as seen by the increase in measured rate constants Further, the accelerated microdroplet hydration can be scaled up to an acetophenone amount of 57.2 ± 0.1 mg min-1 (3.43 ± 0.01 g h-1) by using 2 mol L-1 phenylacetylene sprayed at 300μL min-1. The microdroplet protocol offers several advantages including ultrahigh acceleration, complete conversion, mild reaction conditions (metal, light, and heat free), and minimal post purification, as well as a wide substrate scope, making it attractive for green and sustainable chem. After reading the article, we found that the author used 1-Thiophen-2-yl-ethanone(cas: 88-15-3Reference of 1-Thiophen-2-yl-ethanone)

1-Thiophen-2-yl-ethanone(cas: 88-15-3) belongs to thiophenes. Specialized thiophenes can be synthesized similarly using Lawesson’s reagent as the sulfidizing agent, or via the Gewald reaction, which involves the condensation of two esters in the presence of elemental sulfur. Another method is the Volhard–Erdmann cyclization. Reference of 1-Thiophen-2-yl-ethanone

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

In 2019,Angewandte Chemie, International Edition included an article by Hu, Yanhua; Zhang, Zhenfeng; Zhang, Jian; Liu, Yangang; Gridnev, Ilya D.; Zhang, Wanbin. Reference of 1-Thiophen-2-yl-ethanone. The article was titled 《Cobalt-Catalyzed Asymmetric Hydrogenation of C=N Bonds Enabled by Assisted Coordination and Nonbonding Interactions》. The information in the text is summarized as follows:

An efficient cobalt-catalyzed asym. hydrogenation of C=N bonds has been realized. Chiral hydrazines were obtained in high yields and with excellent enantioselectivities (95-98 % ee). The hydrogenation went smoothly at up to 2000 substrate/catalyst and on a gram scale. The success of this reaction relies on the presence of an NHBz group in the substrates, with the reactivity and enantioselectivity improved by an assisted coordination to the cobalt atom and a nonbonding interaction with the ligand. Furthermore, this reaction has practical applications for the synthesis of several useful chiral nitrogen-containing compounds In addition to this study using 1-Thiophen-2-yl-ethanone, there are many other studies that have used 1-Thiophen-2-yl-ethanone(cas: 88-15-3Reference of 1-Thiophen-2-yl-ethanone) was used in this study.

1-Thiophen-2-yl-ethanone(cas: 88-15-3) belongs to thiophenes. Specialized thiophenes can be synthesized similarly using Lawesson’s reagent as the sulfidizing agent, or via the Gewald reaction, which involves the condensation of two esters in the presence of elemental sulfur. Another method is the Volhard–Erdmann cyclization. Reference of 1-Thiophen-2-yl-ethanone

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

In 2015,Physical Chemistry Chemical Physics included an article by Colella, L.; Brambilla, L.; Nardone, V.; Parisini, E.; Castiglioni, C.; Bertarelli, C.. Quality Control of 2-(Thiophen-3-yl)-1,3-dioxolane. The article was titled 《Outside rules inside: the role of electron-active substituents in thiophene-based heterophenoquinones》. The information in the text is summarized as follows:

The biradicaloid vs. quinoidal character of the ground state of thiophene-based heterophenoquinones bearing donor or acceptor groups is investigated. Keeping the conjugation length fixed, namely, the 5,5′-bis(3,5-di-tert-butyl-4-oxo-2,5-cyclohexadiene-1-ylidene)-2,2′-dihydroxy bithiophene backbone, an opposite effect occurs depending on the donating or withdrawing nature of the substituents. The character of the ground state depends not only on the electronic nature of the substituents but also on their position on the mol. skeleton: donor groups on the 3,3′-positions of the bithiophene central core stabilize a quinoidal ground state, whereas a biradicaloid electronic structure results from the introduction of the same donor groups onto the lateral phenones. Withdrawing groups behave similar to donors, but in the opposite direction. In the part of experimental materials, we found many familiar compounds, such as 2-(Thiophen-3-yl)-1,3-dioxolane(cas: 13250-82-3Quality Control of 2-(Thiophen-3-yl)-1,3-dioxolane)

2-(Thiophen-3-yl)-1,3-dioxolane(cas: 13250-82-3) is one of dioxolane. 1,3-Dioxolane derivatives are recognized as important motifs for the construction of numerous pharmacologically active molecules as antiviral, antifungal, anti-HIV, and adrenoreceptor antagonists.Quality Control of 2-(Thiophen-3-yl)-1,3-dioxolane

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

The author of 《One-Step Synthesis of Thieno[2,3-d]pyrimidin-4(3H)-ones via a Catalytic Four-Component Reaction of Ketones, Ethyl Cyanoacetate, S8, and Formamide》 were Shi, Taoda; Kaneko, Lynn; Sandino, Michael; Busse, Ryan; Zhang, Mae; Mason, Damian; Machulis, Jason; Ambrose, Andrew J.; Zhang, Donna D.; Chapman, Eli. And the article was published in ACS Sustainable Chemistry & Engineering in 2019. COA of Formula: C6H6OS The author mentioned the following in the article:

Thieno[2,3-d]pyrimidin-4(3H)-ones are important pharmacophores that have previously required a three-step synthesis with two chromatog. steps. We herein report a green approach to the synthesis of this pharmacol. important class of compounds, e.g. I, via a catalytic four-component reaction using a ketone, Et cyanoacetate, S8, and formamide. The reported reaction is characterized by step economy, reduced catalyst loading, and easy purification In the experiment, the researchers used many compounds, for example, 1-Thiophen-2-yl-ethanone(cas: 88-15-3COA of Formula: C6H6OS)

1-Thiophen-2-yl-ethanone(cas: 88-15-3) belongs to thiophenes. Reflecting their high stabilities, thiophenes arise from many reactions involving sulfur sources and hydrocarbons, especially unsaturated ones. Thiophenes are classically prepared by the reaction of 1,4-diketones, diesters, or dicarboxylates with sulfidizing reagents such as P4S10 such as in the Paal-Knorr thiophene synthesis. COA of Formula: C6H6OS

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

The author of 《Small isomeric push-pull chromophores based on thienothiophenes with tunable optical (non)linearities》 were Podlesny, Jan; Pytela, Oldrich; Klikar, Milan; Jelinkova, Veronika; Kityk, Iwan V.; Ozga, Katarzyna; Jedryka, Jaroslaw; Rudysh, Myron; Bures, Filip. And the article was published in Organic & Biomolecular Chemistry in 2019. SDS of cas: 13250-82-3 The author mentioned the following in the article:

Fourteen new D-π-A push-pull chromophores based on two isomeric thienothiophene donors and seven acceptors of various electronic natures have been designed and conveniently synthesized. In contrast to known thienothiophene push-pull mols., the prepared small chromophores proved to be organic materials with easily tunable thermal, electrochem. and (non)linear optical properties. It has also been shown that small structural variation may result in significantly improved/varied fundamental properties. Very detailed structure-property relationships were elucidated within the systematically developed series of push-pull mols., which may serve as a useful guide in designing new D-π-A mols. based on fused thiophene scaffolds. In the experiment, the researchers used many compounds, for example, 2-(Thiophen-3-yl)-1,3-dioxolane(cas: 13250-82-3SDS of cas: 13250-82-3)

2-(Thiophen-3-yl)-1,3-dioxolane(cas: 13250-82-3) is one of dioxolane. 1,3-Dioxolane derivatives are recognized as important motifs for the construction of numerous pharmacologically active molecules as antiviral, antifungal, anti-HIV, and adrenoreceptor antagonists.SDS of cas: 13250-82-3

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem