Category: benzothiophene

From One-Pot NH-Sulfoximidations of Thiophene Derivatives to Dithienylethene-Type Photoswitches was written by Verbelen, Bram;Siemes, Eric;Ehnbom, Andreas;Raeuber, Christoph;Rissanen, Kari;Woell, Dominik;Bolm, Carsten. And the article was included in Organic Letters in 2019.Computed Properties of C6H8S The following contents are mentioned in the article:

Thiophene NH-sulfoximines were synthesized using a 1-pot NH-sulfoximidation reaction of thiophenes. The reactivity of the products was studied, and the developed protocols were used for the synthesis of a new class of dithienylethene-type photoswitches containing a sulfoximidoyl group. This study involved multiple reactions and reactants, such as 2,5-Dimethylthiophene (cas: 638-02-8Computed Properties of C6H8S).

2,5-Dimethylthiophene (cas: 638-02-8) belongs to benzothiophene derivatives. Functionalized benzothiophenes are important constructs found in molecules with wide ranging biological activity and in organic materials. The different substitution patterns in these heterocycles offer new opportunities for drug discovery and other applications in materials science.Computed Properties of C6H8S

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Switching of the π-electronic conjugations in the reduction of a dithienylethene-fused p-benzoquinone was written by Saito, Eiji;Ako, Takumi;Kobori, Yasuhiro;Tsuda, Akihiko. And the article was included in RSC Advances in 2017.Application In Synthesis of 2,5-Dimethylthiophene The following contents are mentioned in the article:

The electron accepting character of a dithienylethene-fused p-benzoquinone derivative is significantly reduced upon ring-closing isomerization. Visible light unlocks the π-electronic conjugation of the quinone so it can be utilized for a light-driven oxidation reaction. This study involved multiple reactions and reactants, such as 2,5-Dimethylthiophene (cas: 638-02-8Application In Synthesis of 2,5-Dimethylthiophene).

2,5-Dimethylthiophene (cas: 638-02-8) belongs to benzothiophene derivatives. Benzothiophene is relatively a stable molecule. The core structure is a part of various pharmaceutical substances and natural products. It is found within the chemical structures of pharmaceutical drugs such as zileuton, raloxifene, and sertaconazole, and also BTCP.Application In Synthesis of 2,5-Dimethylthiophene

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Tetrahydrobenzothiophene inhibitors of hepatitis C virus NS5B polymerase was written by LaPorte, M. G.;Lessen, T. A.;Leister, L.;Cebzanov, D.;Amparo, E.;Faust, C.;Ortlip, D.;Bailey, T. R.;Nitz, T. J.;Chunduru, S. K.;Young, D. C.;Burns, C. J.. And the article was included in Bioorganic & Medicinal Chemistry Letters in 2006.Recommanded Product: 95211-67-9 The following contents are mentioned in the article:

A novel series of selective HCV NS5B RNA dependent RNA polymerase inhibitors has been disclosed. These compounds contain an appropriately substituted tetrahydrobenzothiophene scaffold. This communication will detail the SAR and activities of this series. This study involved multiple reactions and reactants, such as Ethyl 2-amino-4-methyl-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate (cas: 95211-67-9Recommanded Product: 95211-67-9).

Ethyl 2-amino-4-methyl-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate (cas: 95211-67-9) belongs to benzothiophene derivatives. Benzothiophene finds use in research as a starting material for the synthesis of larger, usually bioactive structures. The different substitution patterns in these heterocycles offer new opportunities for drug discovery and other applications in materials science.Recommanded Product: 95211-67-9

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

TfOH-Catalyzed Reaction between 3-Diazoindolin-2-imines and Electron-Rich Arenes: Access to 3-Aryl-2-aminoindoles was written by Qi, Jie;Wang, Zaibin;Lang, Bo;Lu, Ping;Wang, Yanguang. And the article was included in Journal of Organic Chemistry in 2017.Product Details of 638-02-8 The following contents are mentioned in the article:

TfOH-catalyzed reactions between 3-diazoindolin-2-imines and electron-rich arenes were disclosed. These metal-free reactions furnished 3-aryl-2-aminoindoles in moderate to excellent yields with the tolerance of a broad range of functional groups. This study involved multiple reactions and reactants, such as 2,5-Dimethylthiophene (cas: 638-02-8Product Details of 638-02-8).

2,5-Dimethylthiophene (cas: 638-02-8) belongs to benzothiophene derivatives. Benzothiophene is a fused ring compound of thiophene ring and benzene ring, which is an important class of heterocycles with advantageous structures. Its aromaticity makes it relatively stable, although as a heterocycle, it has reactive sites which allow for functionalization.Product Details of 638-02-8

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Catalytic Synthesis of Methylthiophenes was written by Mashkina, A. V.;Khairulina, L. N.. And the article was included in Russian Journal of Organic Chemistry in 2018.Computed Properties of C6H8S The following contents are mentioned in the article:

The gas-phase reaction of di-Me disulfide with thiophene over Co/HZSM-5 catalyst in a helium medium under atm. pressure at 250-350° gave a mixture of mono-, di-, tri- and tetramethylthiophenes with an overall selectivity of 94-96%. This study involved multiple reactions and reactants, such as 2,5-Dimethylthiophene (cas: 638-02-8Computed Properties of C6H8S).

2,5-Dimethylthiophene (cas: 638-02-8) belongs to benzothiophene derivatives. Benzothiophenes are valuable heterocycles that are widely used in medicines, agrochemicals, and materials science. It is found within the chemical structures of pharmaceutical drugs such as raloxifene, zileuton, sertaconazole, and also BTCP.Computed Properties of C6H8S

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Electrochemical Radical Selenylation of Alkenes and Arenes via Se-Se Bond Activation was written by Sun, Li;Wang, Liwei;Alhumade, Hesham;Yi, Hong;Cai, Hu;Lei, Aiwen. And the article was included in Organic Letters in 2021.Quality Control of 2,5-Dimethylthiophene The following contents are mentioned in the article:

A novel electrochem. radical selenylation of alkenes and activated arenes without external oxidants is reported. The diselenide was fully transformed into Se-centered radicals through electrochem. Se-Se bond activation. Three-component radical carbonselenation was successfully realized using styrenes to trap the RSe radical. Besides, the direct coupling of RSe radicals with activated arenes was further developed. Using this atom-economic protocol, diversity of unsym. aryl-aryl, aryl-alkyl, and alkyl-alkyl selenoethers was obtained regioselectively, which has potential application in biol. chem. This study involved multiple reactions and reactants, such as 2,5-Dimethylthiophene (cas: 638-02-8Quality Control of 2,5-Dimethylthiophene).

2,5-Dimethylthiophene (cas: 638-02-8) belongs to benzothiophene derivatives. Benzothiophene is relatively a stable molecule. The electrophilic substitution of benzothiophene systems is much less regioselective than that of indoles. It is also used in the manufacturing of dyes such as thioindigo.Quality Control of 2,5-Dimethylthiophene

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Cu(I)-Induced Activation of Furan for Inverse Electron Demand ADAR with Alkenes toward Regioselective Synthesis of Tetrahydropyridine was written by Shukla, Prashant;Asati, Ambika;Bhardiya, Smita R.;Singh, Manorama;Rai, Vijai K.;Rai, Ankita. And the article was included in Journal of Organic Chemistry in 2020.Quality Control of 2,5-Dimethylthiophene The following contents are mentioned in the article:

The aza-Diels-Alder reaction of various alkenes and in situ formed 1-aza-1,3-dienes from the reaction of furan/pyrrole/thiophene and PhINTs for the regioselective synthesis of tetrahydropyridine (THP) derivatives was realized. The reaction was catalyzed by Tp^Me2Cu as a catalyst under very mild reaction conditions. Structurally different alkenes, along with an alkyne, have been utilized as dienophiles to afford a wide range of different THP derivatives up to 70% yield. The potential application of the envisaged method was also investigated by a gram-scale synthesis. This study involved multiple reactions and reactants, such as 2,5-Dimethylthiophene (cas: 638-02-8Quality Control of 2,5-Dimethylthiophene).

2,5-Dimethylthiophene (cas: 638-02-8) belongs to benzothiophene derivatives. Benzothiophenes are valuable heterocycles that are widely used in medicines, agrochemicals, and materials science. It is found within the chemical structures of pharmaceutical drugs such as raloxifene, zileuton, and sertaconazole, and also BTCP.Quality Control of 2,5-Dimethylthiophene

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Novel Small Molecule Inhibitors of MDR Mycobacterium tuberculosis by NMR Fragment Screening of Antigen 85C was written by Scheich, Christoph;Puetter, Vera;Schade, Markus. And the article was included in Journal of Medicinal Chemistry in 2010.Application In Synthesis of Ethyl 2-amino-4-methyl-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate The following contents are mentioned in the article:

Protein target-based discovery of novel antibiotics has been largely unsuccessful despite rich genome information. Particularly in need are new antibiotics for tuberculosis, which kills 1.6 million people annually and shows a rapid increase in multiple-drug-resistant cases. By combining fragment-based drug discovery with early whole cell antibacterial screening, we discovered novel ligand-efficient inhibitors of multiple-drug resistant Mycobacterium tuberculosis (Mtb), which bind to the substrate site of the Mtb protein antigen 85C, hitherto unused in Mtb chemotherapy. This study involved multiple reactions and reactants, such as Ethyl 2-amino-4-methyl-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate (cas: 95211-67-9Application In Synthesis of Ethyl 2-amino-4-methyl-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate).

Ethyl 2-amino-4-methyl-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate (cas: 95211-67-9) belongs to benzothiophene derivatives. Benzothiophene is relatively a stable molecule. The electrophilic substitution of benzothiophene systems is much less regioselective than that of indoles. The different substitution patterns in these heterocycles offer new opportunities for drug discovery and other applications in materials science.Application In Synthesis of Ethyl 2-amino-4-methyl-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Densities at high pressures and derived properties of thiophenes was written by Anton, V.;Lomba, L.;Cea, P.;Giner, B.;Lafuente, C.. And the article was included in Journal of Chemical Thermodynamics in 2017.Electric Literature of C6H8S The following contents are mentioned in the article:

This contribution reports the densities in wide temperature (from 283.15 to 338.15 K) and pressure (from 0.1 to 65.0 MPa) ranges of four members of the thiophene family (thiophene, 2-methylthiophene, 3-methylthiophene and 2,5-dimethylthiophene). These densities have been satisfactorily correlated by means of the TRIDEN equation. From these data, several derived properties as isobaric expansibility, isothermal compressibility, and internal pressure have been estimated Using all these properties, interesting information about mol. organization can be deduced. This study involved multiple reactions and reactants, such as 2,5-Dimethylthiophene (cas: 638-02-8Electric Literature of C6H8S).

2,5-Dimethylthiophene (cas: 638-02-8) belongs to benzothiophene derivatives. Benzothiophenes are valuable heterocycles that are widely used in medicines, agrochemicals, and materials science. It is found within the chemical structures of pharmaceutical drugs such as raloxifene, zileuton, and sertaconazole, and also BTCP.Electric Literature of C6H8S

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Trametes versicolor (L.) mushrooms liquefaction in supercritical solvents: Effects of operating conditions on product yields and chromatographic characterization was written by Durak, Halil. And the article was included in Journal of Supercritical Fluids in 2018.Recommanded Product: 2,5-Dimethylthiophene The following contents are mentioned in the article:

In this study, the effect of reaction temperature, solvent and catalyst were examined on conversion of Trametes versicolor mushroom. Supercritical liquefaction experiments were made in a cylindrical reactor in acetone and isopropanol under supercritical circumstances with (Aluminum oxide, calcium hydroxide) and without catalyst at the temperatures of 250, 270, 290 ^°C. The bio-oils obtained at 250 and 290 °C in liquefaction were analyzed and characterized by chromatog. and spectroscopic techniques containing GC-MS, FT-IR and elemental anal. This study involved multiple reactions and reactants, such as 2,5-Dimethylthiophene (cas: 638-02-8Recommanded Product: 2,5-Dimethylthiophene).

2,5-Dimethylthiophene (cas: 638-02-8) belongs to benzothiophene derivatives. Functionalized benzothiophenes are important constructs found in molecules with wide ranging biological activity and in organic materials. The different substitution patterns in these heterocycles offer new opportunities for drug discovery and other applications in materials science.Recommanded Product: 2,5-Dimethylthiophene

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem