Category: benzothiophene

Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. Recommanded Product: 20503-40-6. Introducing a new discovery about 20503-40-6, Name is 6-Aminobenzo[b]thiophene 1,1-dioxide

Carbonic anhydrase inhibitors: Inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with benzo[b]thiophene 1,1-dioxide sulfonamides

A series of selected benzo[b]thiophene-5- and 6-sulfonamide derivatives previously reported to show cytotoxic activity and some others newly synthesized has been tested for the interactions with several CA isozymes, some of which are known to be involved in tumorigenesis (hCA IX), whereas others are ubiquitously found in many normal tissues (the cytosolic isoforms hCA I and II). The unsubstituted sulfonamides inhibited hCA I with inhibition constants in the range of 63-138 nM, hCA II with inhibition constants in the range of 6.3-8.8 nM, and hCA IX with inhibition constants in the range of 2.8-15 nM, being thus more active than clinically used inhibitors such as acetazolamide, methazolamide, ethoxzolamide, dichlorophenamide or indisulam (E 7070). Some of these derivatives also showed some selectivity for the inhibition of the tumor-associated (hCA IX) over the cytosolic isozyme hCA II. Although these derivatives may act on many targets other than the CAs (such as the NADH oxidase) or may induce apoptosis by accumulation of reactive oxygen species, it is quite important to try to decipher as many as possible of the potential mechanisms that lead to derivatives with potent antitumor activity in order to develop novel therapeutic strategies for the management of cancer.

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Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

 

Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. Recommanded Product: 6-Methoxy-2-(4-methoxyphenyl)-1-benzothiophene. Introducing a new discovery about 63675-74-1, Name is 6-Methoxy-2-(4-methoxyphenyl)-1-benzothiophene

Benzo-thiophene-containing polymerizable compound (by machine translation)

This invention relates to a kind of polymerizable compounds are of formula I, the compounds of formula I can be polymerization and the liquid crystal composition, a liquid crystal display device. wherein X 1? X 7 independently represent H, or F CH 3; Y 1, Y 2 independently represent CH 3, CH 2 F, CHF 2 or CF 3. Is particularly suitable for the application of display or TV PSVA liquid crystal composition, in particular after running for a long time, with no or significantly reduced residual Image (image sticking). (by machine translation)

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Benzothiophene | C8H6S – PubChem

 

Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. HPLC of Formula: C10H8O2S. Introducing a new discovery about 22913-24-2, Name is Methyl benzo[b]thiophene-2-carboxylate

Copper-mediated tandem ring-opening/cyclization reactions of cyclopropanols with aryldiazonium salts: Synthesis of: N -arylpyrazoles

A general method for the synthesis of structurally diverse N-arylpyrazoles from readily available cyclopropanols and aryldiazonium salts is disclosed. The reaction was conducted at room temperature within minutes with a broad substrate scope and excellent regioselectivity.

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Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

 

Application of 4923-87-9, A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 4923-87-9, Name is 5-Bromobenzothiophene, molecular formula is C8H5BrS. In a Article£¬once mentioned of 4923-87-9

Synthesis of Borinic Acids and Borinate Adducts Using Diisopropylaminoborane

In situ formation of aryl Grignard under Barbier condition and diisopropylaminoborane as boron source allows a complete control of the addition onto the boron electrophile. Analytically pure borinic acid derivatives were produced at the gram scale without column chromatography and isolated as borinates adducts, with ethanolamine or 8-hydroxyquinoline, after workup.

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Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

 

Electric Literature of 6287-82-7, A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 6287-82-7, Name is 2,3-Dibromobenzo[b]thiophene, molecular formula is C8H4Br2S. In a Article£¬once mentioned of 6287-82-7

Palladium-catalyzed tandem N-H/C-H arylation: Regioselective synthesis of N-heterocycle-fused phenanthridines as versatile blue-emitting luminophores

A general and highly regioselective synthetic protocol for structurally diverse N-heteroaryl-fused phenanthridines has been developed. Varieties of fluorescence molecules comprising imidazole-fused, benzoimidazole-fused, indole-fused and pyrrole-fused phenanthridines were obtained by this modular approach, some of which exhibit excellent blue-emitting performance, high quantum yields, long fluorescence lifetimes, interesting electrochemical properties, and thermal stabilities.

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Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

 

5394-13-8, Name is 2-Bromobenzo[b]thiophene, belongs to benzothiophene compound, is a common compound. name: 2-Bromobenzo[b]thiopheneIn an article, once mentioned the new application about 5394-13-8.

Intermolecular Reductive Heck Reaction of Unactivated Aliphatic Alkenes with Organohalides

A general intermolecular reductive Heck reaction of organohalides with both terminal and internal unactivated aliphatic alkenes has been first realized in high yield with complete anti-Markovnikov selectivity. The challenging vinyl bromides, aryl chlorides, and polysubstituted internal alkenes were first applied. More than 100 remote carbofunctionalized alkyl carboxylic acid derivatives were rapidly synthesized from easily accessible starting materials. The synthesis of drug molecules has further demonstrated the wide synthetic utility of this scalable strategy. Preliminary mechanistic studies are consistent with the proposed catalytic cycle.

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Benzothiophene – Wikipedia,
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Electric Literature of 6386-80-7, A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 6386-80-7, Name is Benzo[b]thiophene-6-carbaldehyde, molecular formula is C9H6OS. In a Patent£¬once mentioned of 6386-80-7

SUBSTITUTED TRIAZOLE AND IMIDAZOLE COMPOUNDS

The invention is concerned with the compounds of formula (I): and pharmaceutically acceptable salts thereof. In addition, the present invention relates to methods of manufacturing and using the compounds of formula (I) as well as pharmaceutical compositions containing such compounds. The compounds of formula (I) are LMP7 inhibitors and may be useful in treating associated inflammatory diseases and disorders such as, for example, rheumatoid arthritis, lupus and irritable bowel disease.

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Benzothiophene – Wikipedia,
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Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. Quality Control of 5-Bromobenzothiophene. Introducing a new discovery about 4923-87-9, Name is 5-Bromobenzothiophene

Use of Benzo-Heteroaryl Sulfamide Derivatives for Lowering Lipids and Lowering Blood Glucose Levels

The present invention is a method for the glucose related disorders and lipid related disorders comprising administering to a subject in need thereof a therapeutically effective amount of one or more novel b benzo-heteroaryl sulfamide derivatives of formula (I) as herein defined. The present invention is further directed to methods of treatment comprising co-therapy with an anti-diabetic agent, and anti-lipid agent and/or an anti-obesity agent.

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Benzothiophene – Wikipedia,
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Synthetic Route of 10243-15-9, Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. 10243-15-9, Name is 3-Bromo-2-methylbenzo[b]thiophene,introducing its new discovery.

Efficient and Practical Oxidative Bromination and Iodination of Arenes and Heteroarenes with DMSO and Hydrogen Halide: A Mild Protocol for Late-Stage Functionalization

An efficient and practical system for inexpensive bromination and iodination of arenes as well as heteroarenes by using readily available dimethyl sulfoxide (DMSO) and HX (X = Br, I) reagents is reported. This mild oxidative system demonstrates a versatile protocol for the synthesis of aryl halides. HX (X = Br, I) are employed as halogenating reagents when combined with DMSO which participates in the present chemistry as a mild and inexpensive oxidant. This oxidative system is amenable to late-stage bromination of natural products. The kilogram-scale experiment (>95% yield) shows great potential for industrial application.

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Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

 

Chemistry is traditionally divided into organic and inorganic chemistry. Computed Properties of C8H4Br2S, The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent£¬Which mentioned a new discovery about 6287-82-7

Synthesis and properties of symmetric and unsymmetric dibenzothienopyrroles

Symmetrical and unsymmetrical heteroacenes containing thiophene and pyrrole rings were synthesized. The unsymmetrical heteroacene was synthesized in two steps involving an unexpected palladium catalyzed amination of alkyl or aryl amines with benzo[b]thiophene followed by a copper catalyzed coupling. The symmetrical heteroacene was obtained by a palladium catalyzed amination reaction and also by a copper catalyzed amidation reaction. The crystal structure, photophysical and electrochemical properties of symmetrical and unsymmetrical heteroacenes are described.

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Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem