Tag: 200-300

Synthesis of novel benzo[b]furans and benzo[b]thiophenes: analogs of combretastatin and resveratrol was written by Chauhan, Jay;Monteil, Alexandre R.;Patterson, Steven E.. And the article was included in Heterocyclic Communications in 2010.HPLC of Formula: 6287-82-7 This article mentions the following:

A rapid and efficient synthesis of fused polyphenolic/polymethoxy benzofurans and benzothiophenes that have potential as antitumor agents and components of anti-HIV combination therapy was achieved. In the experiment, the researchers used many compounds, for example, 2,3-Dibromobenzo[b]thiophene (cas: 6287-82-7HPLC of Formula: 6287-82-7).

2,3-Dibromobenzo[b]thiophene (cas: 6287-82-7) belongs to benzothiophene derivatives. Benzothiophene is relatively a stable molecule. The electrophilic substitution of benzothiophene systems is much less regioselective than that of indoles. Due to its aromaticity, thiophenes do not exhibit the same properties as conventional thioethers.HPLC of Formula: 6287-82-7

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Benzo[b]thiophenium sulfur-carbon ylides: preparation, structure and comparison with thiophenium analog was written by Vuorinen, Eino;Chalmers, Anthony A.;Dillen, Jan L. M.;Modro, Tomasz A.. And the article was included in Tetrahedron in 1991.Reference of 6287-82-7 This article mentions the following:

A series of new sulfur-carbon ylides I (R¹ = Br, Cl, Me, H, R² = Br, Cl, H, X = OEt, OCMe₃, OMe, Y = Me, OEt, OMe, XY = CH₂CMe₂CH₂) derived from benzo[b]thiophenes II and YCOCN₂COX were prepared and characterized. NMR (¹H, ¹³C) studies revealed that ylides substituted addnl. at position 2 of the thiophene ring can exist as pairs of diastereomers, not interchangeable at room temperature The slow exchange between the two sites was attributed to the restricted rotation about the ylide S-C bond. In the experiment, the researchers used many compounds, for example, 2,3-Dibromobenzo[b]thiophene (cas: 6287-82-7Reference of 6287-82-7).

2,3-Dibromobenzo[b]thiophene (cas: 6287-82-7) belongs to benzothiophene derivatives. Benzothiophene is relatively a stable molecule. The core structure is a part of various pharmaceutical substances and natural products. It is found within the chemical structures of pharmaceutical drugs such as raloxifene, zileuton, and sertaconazole, and also BTCP.Reference of 6287-82-7

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Palladium-Catalyzed Carbonylative Synthesis of Phthalimides from 1,2-Dibromoarenes with Molybdenum Hexacarbonyl as Carbon Monoxide Source was written by Wu, Xiao-Feng;Oschatz, Stefan;Sharif, Muhammad;Flader, Anika;Krey, Lisa;Beller, Matthias;Langer, Peter. And the article was included in Advanced Synthesis & Catalysis in 2013.Category: benzothiophene This article mentions the following:

We describe here a convenient and mild, carbon monoxide gas-free palladium-catalyzed procedure to obtain N-substituted phthalimides with molybdenum hexacarbonyl as carbon monoxide precursor. E.g., in presence of molybdenum hexacarbonyl, Pd(OAc)₂, CataCXium A, and DBU in toluene at 100 °C, reaction of 1,2-Br₂C₆H₄ and BuNH₂ gave 84% phthalimide derivative I. These conditions tolerate a number of functional groups on the benzene ring as well as a number of amines and give the corresponding phthalimides in good to excellent yields. In the experiment, the researchers used many compounds, for example, 2,3-Dibromobenzo[b]thiophene (cas: 6287-82-7Category: benzothiophene).

2,3-Dibromobenzo[b]thiophene (cas: 6287-82-7) belongs to benzothiophene derivatives. Benzothiophenes are valuable heterocycles that are widely used in medicines, agrochemicals, and materials science. It is found within the chemical structures of pharmaceutical drugs such as raloxifene, zileuton, sertaconazole, and also BTCP.Category: benzothiophene

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Optical Properties of Dibenzo[d,d’]thieno[3,2-b;4,5-b’]dithiophene Monocrystals: The Effect of Intermolecular Interactions was written by Alessandrini, Laura;Braga, Daniele;Jaafari, Abdelhafid;Miozzo, Luciano;Mora, Stefano;Silvestri, Leonardo;Tavazzi, Silvia;Yassar, Abderrahim. And the article was included in Journal of Physical Chemistry A in 2011.Formula: C8H4Br2S This article mentions the following:

The polarized UV-visible absorption spectra of dibenzo[d,d’]thieno[3,2-b;4,5-b’]dithiophene single crystals are reported and interpreted to definitively attribute the observed bands and their polarizations. The results provide information on the intermol. interactions and on the aggregation in the condensed phase, which can be of either herringbone- or H-type, depending on the electronic transition taken into considerations, with consequences on the order and polarization of the absorption bands. A relatively easy method is discussed to obtain information on the structural/morphol. properties of different types of samples, including thin films, which were recently proposed for high-performance organic film-effect transistors for their high ionization potential and photostability. In the experiment, the researchers used many compounds, for example, 2,3-Dibromobenzo[b]thiophene (cas: 6287-82-7Formula: C8H4Br2S).

2,3-Dibromobenzo[b]thiophene (cas: 6287-82-7) belongs to benzothiophene derivatives. Benzothiophene scaffolds are of great importance due to its increased presence in bioactive molecules. It has been used as a raw material for the synthesis of biologically active structures and is found in pharmaceuticals such as leukotriene synthesis inhibitors and antifungals, as well as in many natural products.Formula: C8H4Br2S

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Photoinduced Refractive Index Change of a Photochromic Diarylethene Polymer was written by Kim, Eunkyoung;Choi, Yun-Ki;Lee, Myung-Hyun. And the article was included in Macromolecules in 1999.Recommanded Product: 10243-15-9 This article mentions the following:

The effect of photoirradiation on the refractive index of a diarylethene polymer was studied. The diarylethene polymer was prepared by a radical polymerization using 1-[6′-(methacryoyloxyethyloxycarbonyl)-2′-methylbenzo[b]thiophen-3′-yl]-2-(2”-methylbenzo[b]thiophen-3”-yl) hexafluorocyclopentene (BTF6MA), styrene, and Bu methacrylate. A colorless film prepared from the diarylethene polymer turned a deep red hue upon exposure to UV light. The red color was immediately bleached by visible light, and such coloration and bleaching of the polymer film could be switched reversibly by using two light source of UV and visible light. The refractive index (n_TE) of the polymer film, with 5.3 mol % of BTF6MA, was determined as 1.5555 and 1.5459 by a prism coupler using TE polarized light of 633 and 830 nm, resp. Upon irradiation with light of 365 nm, the refractive index was increased, resulting in a photoinduced refractive index change (Δn_TE) of 8 × 10^-4 as monitored by light of 830 nm. Δn_TE was dependent on the wavelength of the monitoring light. The dispersion of light in the diarylethene polymer film could be simulated by the Sellmeier equation, n_λ² = n_∞² + Dλ₀²/ (λ² – λ₀²), in which the refractive index at longest wavelength limit (n_∞) and the oscillator strength (D) for the colorless polymer film were determined as 1.5356 and 0.18, resp. Similarly, n_∞ and D values for the red polymer film, prepared by UV irradiation, were determined as 1.5368 and 0.042, resp. In the experiment, the researchers used many compounds, for example, 3-Bromo-2-methylbenzo[b]thiophene (cas: 10243-15-9Recommanded Product: 10243-15-9).

3-Bromo-2-methylbenzo[b]thiophene (cas: 10243-15-9) belongs to benzothiophene derivatives. Benzothiophene is relatively a stable molecule. The electrophilic substitution of benzothiophene systems is much less regioselective than that of indoles. Due to its aromaticity, thiophenes do not exhibit the same properties as conventional thioethers.Recommanded Product: 10243-15-9

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Synthesis and Application of 1-[(2-methyl-3-benzothiophene)]-2-[2-methyl-5-(1,3-dioxolane)-3-thienyl]perfluorocyclopentene was written by Fu, Yinglong;Zhou, Lingyao;Fan, Congbin;Pu, Shouzhi. And the article was included in Advanced Materials Research (Durnten-Zurich, Switzerland) in 2015.Electric Literature of C9H7BrS This article mentions the following:

A new unsym. photochromic diarylethene I was synthesized and its photochromic and fluorescence properties were investigated in detail. The results showed this compound exhibited reversible photochromism, undergoing reversible cyclization and cycloreversion reactions upon alternating irradiation with UV and visible light in solution Compound I changed from colorless to pink upon irradiation with 297 nm UV light, in which absorption maxima were observed at 516 nm in acetonitrile. In the experiment, the researchers used many compounds, for example, 3-Bromo-2-methylbenzo[b]thiophene (cas: 10243-15-9Electric Literature of C9H7BrS).

3-Bromo-2-methylbenzo[b]thiophene (cas: 10243-15-9) belongs to benzothiophene derivatives. Benzothiophenes are valuable heterocycles that are widely used in medicines, agrochemicals, and materials science. It is found within the chemical structures of pharmaceutical drugs such as zileuton, raloxifene, and sertaconazole, and also BTCP.Electric Literature of C9H7BrS

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Materials with synthesis and properties of photochromic diarylethene was written by Xue, Yaming;Sun, Fengxia;Pu, Shouzhi. And the article was included in Applied Mechanics and Materials in 2014.Recommanded Product: 10243-15-9 This article mentions the following:

An unsym. photochromic diarylethene was synthesized and its photochromism properties were investigated in detail. The compound exhibited remarkable photochromism, changing from colorless to light pink after irradiation with 297 nm UV light, in which absorption maxima were observed at 498 nm in hexane and at 505 nm in PMMA amorphous films, resp. The photochromic reaction kinetics was studied in solution and their cyclization/cycloreversion processes belong to zeroth/first order reaction in hexane. In the experiment, the researchers used many compounds, for example, 3-Bromo-2-methylbenzo[b]thiophene (cas: 10243-15-9Recommanded Product: 10243-15-9).

3-Bromo-2-methylbenzo[b]thiophene (cas: 10243-15-9) belongs to benzothiophene derivatives. Benzothiophene is a fused ring compound of thiophene ring and benzene ring, which is an important class of heterocycles with advantageous structures. The different substitution patterns in these heterocycles offer new opportunities for drug discovery and other applications in materials science.Recommanded Product: 10243-15-9

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

CYP17 inhibitors. Annulations of additional rings in methylene imidazole substituted biphenyls: synthesis, biological evaluation and molecular modeling was written by Pinto-Bazurco Mendieta, Mariano A. E.;Negri, Matthias;Hu, Qingzhong;Hille, Ulrike E.;Jagusch, Carsten;Jahn-Hoffmann, Kerstin;Mueller-Vieira, Ursula;Schmidt, Dirk;Lauterbach, Thomas;Hartmann, Rolf W.. And the article was included in Archiv der Pharmazie (Weinheim, Germany) in 2008.Quality Control of Methyl 5-bromobenzo[b]thiophene-2-carboxylate This article mentions the following:

Twenty-one novel compounds originating from two classes of annulated biphenyls were synthesized as mimetics of the steroidal A- and C-rings and examined for their potency as inhibitors of human CYP17. Selected compounds were tested for inhibition of the hepatic CYP enzyme 3A4. Potent CYP17 inhibitors were found for each class, compound I (17 and 71% at 0.2 and 2 μM, resp.) and II (591 nM). Compound II showed only weak inhibition of CYP3A4 (32 and 64% at 2 and 10 μM, resp.). Both compounds, however, exhibited moderate to strong inhibition of the glucocorticoid-forming enzyme CYP11B1. The most interesting compounds were docked into our protein model. They bound into one of the modes which we have previously published. New interaction regions were identified. In the experiment, the researchers used many compounds, for example, Methyl 5-bromobenzo[b]thiophene-2-carboxylate (cas: 7312-11-0Quality Control of Methyl 5-bromobenzo[b]thiophene-2-carboxylate).

Methyl 5-bromobenzo[b]thiophene-2-carboxylate (cas: 7312-11-0) belongs to benzothiophene derivatives. Benzothiophene is relatively a stable molecule. The electrophilic substitution of benzothiophene systems is much less regioselective than that of indoles. It is found within the chemical structures of pharmaceutical drugs such as zileuton, raloxifene, and sertaconazole, and also BTCP.Quality Control of Methyl 5-bromobenzo[b]thiophene-2-carboxylate

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Photomobile Polymer Materials: Photoresponsive Behavior of Cross-Linked Liquid-Crystalline Polymers with Mesomorphic Diarylethenes was written by Mamiya, Jun-ichi;Kuriyama, Akito;Yokota, Naoki;Yamada, Munenori;Ikeda, Tomiki. And the article was included in Chemistry – A European Journal in 2015.SDS of cas: 10243-15-9 This article mentions the following:

Cross-linked liquid-crystalline (LC) polymers with a mesomorphic diarylethene were prepared to demonstrate a versatile strategy for cross-linked photochromic LC polymers as photomobile materials. Upon exposure to UV light to cause photocyclization of the diarylethene chromophore, the cross-linked polymer films bend toward an actinic light source. By irradiation with visible light to cause a closed-ring to open-ring isomerization, the bent films revert to the initial flat state. Without visible-light irradiation, the bent films remain bent even at 120 °C, indicating high thermal stability of the cross-linked diarylethene LC polymers. In the experiment, the researchers used many compounds, for example, 3-Bromo-2-methylbenzo[b]thiophene (cas: 10243-15-9SDS of cas: 10243-15-9).

3-Bromo-2-methylbenzo[b]thiophene (cas: 10243-15-9) belongs to benzothiophene derivatives. Benzothiophene scaffolds are of great importance due to its increased presence in bioactive molecules. Its aromaticity makes it relatively stable, although as a heterocycle, it has reactive sites which allow for functionalization.SDS of cas: 10243-15-9

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Synthesis and properties research of a photochromic diarylethene bearing a ethynyl moiety was written by Sun, Fengxia;Cui, Shiiqiang;Pu, Shouzhi. And the article was included in Advanced Materials Research (Durnten-Zurich, Switzerland) in 2014.SDS of cas: 10243-15-9 This article mentions the following:

A new unsym. photochromic diarylethene compound, 1-(2-Methyl-3-benzothiophene)-2-(5-(4-ethynyl)-2-methylthiophen-3-yl) Perfluorocyclopentene (1o), was synthesized and its photochem., fluorescence properties were investigated systematically both in solution and PMMA amorphous film. The results showed that this compound exhibited reversible photochromism, changing from colorless to pink after irradiation with 297 nm UV light both in solution and in PMMA amorphous film. The photochromic reaction kinetics indicated that the cyclization processes of 1 belong to the zeroth order reaction and the cycloreversion process belong to the first order reaction. In the experiment, the researchers used many compounds, for example, 3-Bromo-2-methylbenzo[b]thiophene (cas: 10243-15-9SDS of cas: 10243-15-9).

3-Bromo-2-methylbenzo[b]thiophene (cas: 10243-15-9) belongs to benzothiophene derivatives. Benzothiophene finds use in research as a starting material for the synthesis of larger, usually bioactive structures. The different substitution patterns in these heterocycles offer new opportunities for drug discovery and other applications in materials science.SDS of cas: 10243-15-9

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem