Tag: 200-300

Unimolecular heteroaromatic photoinitiators was written by Neckers, Douglas C.;Wagenaar, Frank L.. And the article was included in Tetrahedron Letters in 1984.Recommanded Product: 2,3-Dibromobenzo[b]thiophene This article mentions the following:

The synthesis and use for polymerization of new photoinitiators, I  [92613-07-5] and II  [92613-08-6] based on benzo[b]thiophene, is reported. The effectiveness of I and II for polymerization of Me methacrylate is compared to that of 2,3-dibromobenzo[b]thiophene  [6287-82-7]. In the experiment, the researchers used many compounds, for example, 2,3-Dibromobenzo[b]thiophene (cas: 6287-82-7Recommanded Product: 2,3-Dibromobenzo[b]thiophene).

2,3-Dibromobenzo[b]thiophene (cas: 6287-82-7) belongs to benzothiophene derivatives. Benzothiophene is relatively a stable molecule. The electrophilic substitution of benzothiophene systems is much less regioselective than that of indoles. It has been used as a raw material for the synthesis of biologically active structures and is found in pharmaceuticals such as leukotriene synthesis inhibitors and antifungals, as well as in many natural products.Recommanded Product: 2,3-Dibromobenzo[b]thiophene

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Metal-directed synthesis of quadruple-stranded helical Eu(III) molecular switch: a significant improvement in photocyclization quantum yield was written by Zhang, Yuan;Zhou, Yanyan;Gao, Ting;Yan, Pengfei;Li, Hongfeng. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2020.Product Details of 10243-15-9 This article mentions the following:

The self-assembly of a quadruple-stranded Eu(III) helicate induces the conformation transformation of a DAE-based photochromic ligand from parallel to antiparallel, which brings a significant improvement in the photocyclization quantum yield (Φ_o-c) as compared with the free ligand. Furthermore, the photocontrolled open- and closed-rings of the ligand realized a reversible modulation toward Eu³⁺ center emission. In the experiment, the researchers used many compounds, for example, 3-Bromo-2-methylbenzo[b]thiophene (cas: 10243-15-9Product Details of 10243-15-9).

3-Bromo-2-methylbenzo[b]thiophene (cas: 10243-15-9) belongs to benzothiophene derivatives. Benzothiophene is a fused ring compound of thiophene ring and benzene ring, which is an important class of heterocycles with advantageous structures. It is found within the chemical structures of pharmaceutical drugs such as raloxifene, zileuton, and sertaconazole, and also BTCP.Product Details of 10243-15-9

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Synthesis of novel 2-aminoimidazo[4,5-b]pyridines, including the thieno analogue of the cooked-food mutagen IFP was written by Bjoerk, Malin;Grivas, Spiros. And the article was included in Journal of Heterocyclic Chemistry in 2006.Formula: C8H4Br2S This article mentions the following:

Eight new compounds, including three new ring systems obtained via the Friedlaender condensation of ortho-aminothiophenecarbaldehydes with creatinine, are reported. The condensation afforded I, which is the thieno analog of the cooked-food mutagen IFP (2-amino-1,6-dimethylfuro[2,3-e]imidazo[4,5-b]pyridine), and the benzothieno[2,3-e]- and benzothieno[3,2-e]imidazo[4,5-b]pyridines. Attempts to condense II with isocreatinine were unsuccessful. Desulfurization of III gave the known cooked-food carcinogen PhIP. The 2-nitro and 2-hydroxy derivatives of III are reported. The related 2-amino-1-methyl-imidazo[4,5-b]benzothiophene was synthesized by a different route. Fully assigned ¹H and ¹³C NMR data of all new compounds are reported. In the experiment, the researchers used many compounds, for example, 2,3-Dibromobenzo[b]thiophene (cas: 6287-82-7Formula: C8H4Br2S).

2,3-Dibromobenzo[b]thiophene (cas: 6287-82-7) belongs to benzothiophene derivatives. Benzothiophene is relatively a stable molecule. The core structure is a part of various pharmaceutical substances and natural products. Due to its aromaticity, thiophenes do not exhibit the same properties as conventional thioethers.Formula: C8H4Br2S

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Synthesis and characterization of unsymmetrical diarylethene based on phenylpentane was written by Zhang, Xiaodong;Wei, Shasha;Pu, Shouzhi. And the article was included in Applied Mechanics and Materials in 2015.Quality Control of 3-Bromo-2-methylbenzo[b]thiophene This article mentions the following:

An unsym. photochromic diarylethene, 1-[2-methyl-3-benzothiophene]-2-[2-methyl-5-(4-pentylphenyl)-3-thienyl]perfluorocyclopentene, has been synthesized, and its properties including photochromism and fluorescence have been investigated. The results showed that this compound undergo reversible cyclization and cycloreversion reactions upon alternating irradiation with UV and visible light in solution In the experiment, the researchers used many compounds, for example, 3-Bromo-2-methylbenzo[b]thiophene (cas: 10243-15-9Quality Control of 3-Bromo-2-methylbenzo[b]thiophene).

3-Bromo-2-methylbenzo[b]thiophene (cas: 10243-15-9) belongs to benzothiophene derivatives. Benzothiophene scaffolds are of great importance due to its increased presence in bioactive molecules. Its aromaticity makes it relatively stable, although as a heterocycle, it has reactive sites which allow for functionalization.Quality Control of 3-Bromo-2-methylbenzo[b]thiophene

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Ullmann-Type Intramolecular C-O Reaction Toward Thieno[3,2-b]furan Derivatives with up to Six Fused Rings was written by Chen, Daoliang;Yuan, Dafei;Zhang, Cheng;Wu, Hao;Zhang, Jianyun;Li, Baolin;Zhu, Xiaozhang. And the article was included in Journal of Organic Chemistry in 2017.Safety of 2,3-Dibromobenzo[b]thiophene This article mentions the following:

In the presence of CuI and 1,10-phenanthroline, (fused) bromothienyl phenols such as I underwent intramol. Ullman coupling mediated by either K₂CO₃ or NaHCO₃ in DMF to yield (fused) thienofurans such as II and III in 47-97% yields. The (fused) bromothienyl phenol reactants were prepared by regioselective Suzuki coupling of hydroxyphenylboronic acids with dibromothiophenes. The structures of II, III, and two dibenzothienofurans were determined by X-ray crystallog. The HOMO and LUMO energies were calculated for selected compounds, including III; the oxidation and reduction potentials of III were determined An organic field-effect transistor was prepared using III which exhibited p-type behavior. In the experiment, the researchers used many compounds, for example, 2,3-Dibromobenzo[b]thiophene (cas: 6287-82-7Safety of 2,3-Dibromobenzo[b]thiophene).

2,3-Dibromobenzo[b]thiophene (cas: 6287-82-7) belongs to benzothiophene derivatives. Functionalized benzothiophenes are important constructs found in molecules with wide ranging biological activity and in organic materials. Its aromaticity makes it relatively stable, although as a heterocycle, it has reactive sites which allow for functionalization.Safety of 2,3-Dibromobenzo[b]thiophene

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Reinvestigating Old Pharmacophores: Are 4-Aminoquinolines and Tetraoxanes Potential Two-Stage Antimalarials? was written by Terzic, Natasa;Konstantinovic, Jelena;Tot, Miklos;Burojevic, Jovana;Djurkovic-Djakovic, Olgica;Srbljanovic, Jelena;Stajner, Tijana;Verbic, Tatjana;Zlatovic, Mario;Machado, Marta;Albuquerque, Ines S.;Prudencio, Miguel;Sciotti, Richard J.;Pecic, Stevan;D’Alessandro, Sarah;Taramelli, Donatella;Solaja, Bogdan A.. And the article was included in Journal of Medicinal Chemistry in 2016.Quality Control of Methyl 5-bromobenzo[b]thiophene-2-carboxylate This article mentions the following:

The syntheses and antiplasmodial activities of various substituted aminoquinolines coupled to an adamantane carrier are described. The compounds exhibited pronounced in vitro and in vivo activity against Plasmodium berghei in the Thompson test. Tethering a fluorine atom to the aminoquinoline C(3) position afforded fluoroaminoquinolines that act as intrahepatocytic parasite inhibitors, with compound 25 having an IC₅₀ = 0.31 μM and reducing the liver load in mice by up to 92% at 80 mg/kg dose. Screening our peroxides as inhibitors of liver stage infection revealed that the tetraoxane pharmacophore itself is also an excellent liver stage P. berghei inhibitor (78: IC₅₀ = 0.33 μM). Up to 91% reduction of the parasite liver load in mice was achieved at 100 mg/kg. Examination of tetraoxane 78 against the transgenic 3D7 strain expressing luciferase under a gametocyte-specific promoter revealed its activity against stage IV-V Plasmodium falciparum gametocytes (IC₅₀ = 1.16 ± 0.37 μM). To the best of our knowledge, compounds 25 and 78 are the first examples of either an 4-aminoquinoline or a tetraoxane liver stage inhibitors. In the experiment, the researchers used many compounds, for example, Methyl 5-bromobenzo[b]thiophene-2-carboxylate (cas: 7312-11-0Quality Control of Methyl 5-bromobenzo[b]thiophene-2-carboxylate).

Methyl 5-bromobenzo[b]thiophene-2-carboxylate (cas: 7312-11-0) belongs to benzothiophene derivatives. Benzothiophene is a fused ring compound of thiophene ring and benzene ring, which is an important class of heterocycles with advantageous structures. Its aromaticity makes it relatively stable, although as a heterocycle, it has reactive sites which allow for functionalization.Quality Control of Methyl 5-bromobenzo[b]thiophene-2-carboxylate

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Transition-metal-free decarboxylative bromination of aromatic carboxylic acids was written by Quibell, Jacob M.;Perry, Gregory J. P.;Cannas, Diego M.;Larrosa, Igor. And the article was included in Chemical Science in 2018.Synthetic Route of C8H4Br2S This article mentions the following:

A transition metal-free decarboxylative bromination of aromatic acids was reported. The reaction is applicable to many electron-rich aromatic and heteroaromatic acids which have previously proved poor substrates for Hunsdiecker-type reactions. In addition, our preliminary mechanistic study suggested that radical intermediates are not involved in this reaction, which is in contrast to classical Hunsdiecker-type reactivity. Overall, the process demonstrates a useful method for producing valuable reagents from inexpensive and abundant starting materials. In the experiment, the researchers used many compounds, for example, 2,3-Dibromobenzo[b]thiophene (cas: 6287-82-7Synthetic Route of C8H4Br2S).

2,3-Dibromobenzo[b]thiophene (cas: 6287-82-7) belongs to benzothiophene derivatives. Benzothiophene finds use in research as a starting material for the synthesis of larger, usually bioactive structures. It is found within the chemical structures of pharmaceutical drugs such as zileuton, raloxifene, and sertaconazole, and also BTCP.Synthetic Route of C8H4Br2S

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Synthesis and reactions of 2,3,5,6-tetrahydro-2,5-ethano-3-benzazocin-4(1H)-one and a thieno-extended analog: x-ray structure of 3-methyl-2,3,5,6-tetrahydro-2,5-ethano[1]benzothieno[3,2-d]azocin-4(1H)-one was written by Iddon, Brian;Redhouse, Alan D.;Yat, Patrick N.. And the article was included in Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999) in 1990.Recommanded Product: 6287-82-7 This article mentions the following:

Hexahydromethanobenzocyclooctenone I (X = O) was prepared by condensation of o-xylene-α,α’-diyl dibromide with N-cyclopentylidenepyrrolidine and converted by Beckmann rearrangement of I (X = NOH) into tetrahydroethanobenzazocinone II (R = H). 2,3-Bis(bromomethyl)benzo[b]thiophene was converted similarly into a mixture of tetrahydroethanobenzothienoazocinones III (X¹ = NH, X² = CO; X¹ = CO, X² = NH). II (R = H) was N-methylated and II (R = H, Me) were reduced with LiAlH₄ to the saturated products. Conversion of II (R = H) into the corresponding thiolactam with P₂S₅ followed by alkylation gave an N– or S-alkylated derivative, (e.g., IV, R = Me, Et), depending on the reagent and reaction conditions. The structures of a number of compounds in this work are based on the x-ray anal. of III (X¹ = CO, X² = NMe). In the experiment, the researchers used many compounds, for example, 2,3-Dibromobenzo[b]thiophene (cas: 6287-82-7Recommanded Product: 6287-82-7).

2,3-Dibromobenzo[b]thiophene (cas: 6287-82-7) belongs to benzothiophene derivatives. Benzothiophenes are valuable heterocycles that are widely used in medicines, agrochemicals, and materials science. It is also used in the manufacturing of dyes such as thioindigo.Recommanded Product: 6287-82-7

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Birch-Type Photoreduction of Arenes and Heteroarenes by Sensitized Electron Transfer was written by Chatterjee, Anamitra;Koenig, Burkhard. And the article was included in Angewandte Chemie, International Edition in 2019.Formula: C8H4Br2S This article mentions the following:

In the presence of Ir[dF(CF₃)ppy]₂(dtbbpy)(PF₆), arenes such as anthracene underwent photochem. Birch reduction mediated by DIPEA and methylamine hydrochloride in DMF under 455 nm light to yield reduced arenes such as 9,10-dihydroanthracene using the accumulated energy of two photons per reduction Mechanistic investigations confirm that the combination of energy-transfer and electron-transfer processes generates an arene radical anion, which is subsequently trapped by hydrogen-atom transfer and finally protonated to form the dearomatized product. In the experiment, the researchers used many compounds, for example, 2,3-Dibromobenzo[b]thiophene (cas: 6287-82-7Formula: C8H4Br2S).

2,3-Dibromobenzo[b]thiophene (cas: 6287-82-7) belongs to benzothiophene derivatives. Benzothiophenes are valuable heterocycles that are widely used in medicines, agrochemicals, and materials science. The different substitution patterns in these heterocycles offer new opportunities for drug discovery and other applications in materials science.Formula: C8H4Br2S

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Phosphorus-Based Heteropentacenes: Efficiently Tunable Materials for Organic n-Type Semiconductors was written by Dienes, Yvonne;Eggenstein, Matthias;Karpati, Tamas;Sutherland, Todd C.;Nyulaszi, Laszlo;Baumgartner, Thomas. And the article was included in Chemistry – A European Journal in 2008.Recommanded Product: 6287-82-7 This article mentions the following:

Benzo-condensed dithieno[3,2-b:2′,3′-d]phospholes were synthesized that allow convenient tuning of properties that are essential for application as semiconductor materials in organic field-effect transistor (OFET) devices. The versatile reactivity of the trivalent P atom in these heteropentacenes provides access to materials that show different photophys. properties, significantly different organization in the solid state, and distinctly different electrochem. properties that can be achieved by simple chem. modifications. The materials show strong photoluminescence in solution and in the solid state that depends on the electronic nature of the P center. Electrochem. studies revealed that the P atom intrinsically furnishes materials with n-channel or ambipolar behavior, also depending on its electronic nature. The exptl. data were verified by DFT quantum chem. calculations and suggest that the P-based heteropentacenes could be excellent candidates for n-channel OFET semiconductor materials. In the experiment, the researchers used many compounds, for example, 2,3-Dibromobenzo[b]thiophene (cas: 6287-82-7Recommanded Product: 6287-82-7).

2,3-Dibromobenzo[b]thiophene (cas: 6287-82-7) belongs to benzothiophene derivatives. Benzothiophene is relatively a stable molecule. The electrophilic substitution of benzothiophene systems is much less regioselective than that of indoles. It is found within the chemical structures of pharmaceutical drugs such as raloxifene, zileuton, sertaconazole, and also BTCP.Recommanded Product: 6287-82-7

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem