Tag: M.W:100-200

17402-83-4, Catalysts function by providing an alternate reaction mechanism that has a lower activation energy than would be found in the absence of the catalyst. In some cases, the catalyzed mechanism may include additional steps.In a article, 17402-83-4, molcular formula is C8H7NS, introducing its new discovery.

SUBSTITUTED BICYCLIC HETEROARYL COMPOUNDS

Disclosed are azaindazole compounds of Formula (I): or a pharmaceutically acceptable salt thereof, wherein: X is O and Y is N; or X is S and Y is CH; Z is CR2 or N; Q is a heteroaryl; and R1 is defined herein. Also disclosed are methods of using such compounds in the treatment of at least one CYP 17 associated condition, such as, for example, cancer, and pharmaceutical compositions comprising such compounds.

Because enzymes can increase reaction rates by enormous factors and tend to be very specific, 17402-83-4, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 17402-83-4

Reference£º
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

 

In homogeneous catalysis, the catalyst is in the same phase as the reactant. The number of collisions between reactants and catalyst is at a maximum.In a patent, 19301-35-0, name is Benzo[b]thiophen-5-ol, introducing its new discovery. 19301-35-0

Substituted 5-hydroxy-2,3-dihydrobenzothiophenes as inhibitors of leukotriene biosynthesis

Position-4 and/or position-6 substituted 5-hydroxy-2,3-dihydrobenzothiophenes and analogs of the following general structural formula (I) are disclosed: STR1 These compounds are found to be potent inhibitors of leukotriene biosynthesis.

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.19301-35-0, you can also check out more blogs about19301-35-0

Reference£º
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

 

The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.310466-38-7, Name is 4-Fluorobenzo[b]thiophene, molecular formula is C8H5FS, 310466-38-7. In a Article, authors is Takeuchi, Kumiko£¬once mentioned of 310466-38-7

Advances toward new antidepressants beyond SSRIs: 1-aryloxy-3-piperidinylpropan-2-ols with dual 5-HT1A receptor antagonism/SSRI activities. Part 1

A series of 1-aryloxy-3-piperidinylpropan-2-ols possessing potent dual 5-HT1A receptor antagonism and serotonin reuptake inhibition was discovered. 1-(1H-Indol-4-yloxy)-3-(4-benzo[b]thiophen-2-ylpiperidinyl)propan-2-ols exhibited selective and high affinity at the 5-HT1A receptor and serotonin reuptake inhibition at nanomolar concentrations for dual activities.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.310466-38-7. In my other articles, you can also check out more blogs about 310466-38-7

Reference£º
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

 

Chemistry is traditionally divided into organic and inorganic chemistry. 17402-83-4, The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent£¬Which mentioned a new discovery about 17402-83-4

This new pharmaceutical use (6-1, 6-dihydro-2-yl) amide derivative, as the inhibitor of this preparation and AKT (PKB) phosphoenzyme (by machine translation)

The invention relates to the novel materials of formula (I), wherein each of the substituents R, R1, R2, R3, R4 and R5 is as defined herein. The materials are useful as inhibitors of AKT(PKB) phosphorylation.

One of the oldest and most widely used commercial enzyme inhibitors is aspirin, 17402-83-4, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 17402-83-4

Reference£º
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

 

Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Article, the author is Galenko, Ekaterina E. and a compound is mentioned, 22913-24-2, Methyl benzo[b]thiophene-2-carboxylate, introducing its new discovery. 22913-24-2

Synthesis and Intramolecular Azo Coupling of 4-Diazopyrrole-2-carboxylates: Selective Approach to Benzo and Hetero [c]-Fused 6H-Pyrrolo[3,4-c]pyridazine-5-carboxylates

A high yield synthesis of fluorescent benzo, thieno, and furo [c]-fused methyl 7-aryl-6H-pyrrolo[3,4-c]pyridazine-5-carboxylates, including unprecedented heterocyclic skeletons, was performed by the transformation of methyl 4-aminopyrrole-2-carboxylate into the corresponding diazo compound, followed by intramolecular azo coupling under acid conditions onto a nucleophilic aryl or hetaryl group in the 3-position. Azo coupling is completely regioselective and, according to DFT calculations, a kinetically controlled reaction. N-Methylation of 1,3-disubstituted 2H-pyrrolo[3,4-c]cinnolines occurs selectively at N5 under kinetic control, leading exclusively to 5-methyl-5H-pyrrolo[3,4-c]cinnoline derivatives.

Interested yet? Keep reading other articles of 1008-75-9!, 22913-24-2

Reference£º
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

 

17402-83-4, Catalysts function by providing an alternate reaction mechanism that has a lower activation energy than would be found in the absence of the catalyst. In a patent, 17402-83-4, molecular formula is C8H7NS, introducing its new discovery.

Herbicides

The invention provides certain herbicidal thiazolotriazole sulphonamides, processes for their preparation, and compositions containing them, the compounds being of the formula: STR1 where: R1 and R2, which may be the same or different, each represent hydrogen, hydroxy, halo, cyano, substituted or unsubstituted alkyl, alkoxy, alkenyloxy, alkynyloxy, aryl, aralkyl, heteroaryl or carbamoyl, or a group –CORa or –CO2 Ra or where Ra is hydrogen or alkyl; or R1 and R2 together represent an alkylene chain of 3 or 4 carbon atoms; R3 represents a substituted or unsubstituted aryl, heterocyclyl or benzheterocyclyl group; and R4 represents hydrogen, an alkali-metal atom, an ammonium group, a substituted or unsubstituted alkyl, alkenyl, alkynyl, acyl, alkoxycarbonyl or aralkyl group, a heterocyclic group, or a group of the formula: STR2 where R1 and R2 are as defined hereinbefore.

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.17402-83-4, you can also check out more blogs about17402-83-4

Reference£º
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

 

130-03-0, Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. 130-03-0, Name is Benzo[b]thiophen-3(2H)-one, molecular formula is C8H6OS. In a Article, authors is Morizur, Vincent£¬once mentioned of 130-03-0

Catalysis of the acylation of aromatic derivatives by metallic tosylates

A series of metallic tosylates were prepared by ultrasonic metal activation and were further used as efficient catalysts for the acylation of aromatic derivatives.

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. 130-03-0, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 130-03-0, in my other articles.

Reference£º
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

 

Chemistry is traditionally divided into organic and inorganic chemistry. 20503-40-6, The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent£¬Which mentioned a new discovery about 20503-40-6

STAT3 INHIBITOR

Provided are STAT3 inhibitors and methods of treating inflammation or a hyperproliferative disease such as, e.g., cancer. In some aspects, compounds may be used to treat breast cancer, a head/neck cancer, a lung cancer, a prostate cancer, or pancreatic cancer.

One of the oldest and most widely used commercial enzyme inhibitors is aspirin, 20503-40-6, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 20503-40-6

Reference£º
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

 

In an article, published in an article,authors is Bonini, Carlo, once mentioned the application of 17402-83-4, Name is Benzo[b]thiophen-4-amine,molecular formula is C8H7NS, is a conventional compound. this article was the specific content is as follows. 17402-83-4

Smiles rearrangement for the synthesis of 5-amino-substituted [1]benzothieno[2,3-b]pyridine

The Smiles rearrangement was successfully applied to 4-hydroxybenzo[b]thiophene furnishing a facile entry to the 4-amino derivative. The rearrangement was extended to 5-methoxy-4-methoxycarbonyl[1]benzothieno[2,3-b]pyridine obtained via aza-Wittig/electrocyclization reaction of novel N-(4-methoxybenzothiophen-2-yl)iminomethyldiphenylphosphorane with methyl trans-4-oxo-2-pentenoate. The preparation of a novel 5-amino-4-methoxycarbonyl[1]benzothieno[2,3-b]pyridine, which is of interest as a potential secondary peptide structure mimic, was successfully achieved.

If you are interested in 17402-83-4, you can contact me at any time and look forward to more communication. 17402-83-4

Reference£º
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

 

6314-28-9,6314-28-9, Benzo[b]thiophene-2-carboxylic acid is a benzothiophene compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

Benzo [b] thiophene-2-carboxylic acid (159 mg, 0.892 mmol), 2-amino-biphenyl (156 mg, 0.922 mmol), DCC (393 mg, 1.90mmol) and DMAP (26 mg, 0.21 mmol) It was dissolved in dichloromethane (20 mL), and stirred for 14 hours at room temperature. when thin layer chromatography (TLC) check when, a new spot is generated, and then adding water to the reaction mixture, dichloromethane comingAnd extracted twice with. The extracted organic layer was dried over magnesium sulfate and concentrated under reduced pressure. Column The concentrated reaction mixture was purified by chromatography (silica gel, ethyl acetate / n- hexane = 1/9) to obtain the object compound (102 mg, 35%) as a white solid.

6314-28-9 Benzo[b]thiophene-2-carboxylic acid 95864, abenzothiophene compound, is more and more widely used in various fields.

Reference£º
Patent; KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY; JUNG, YOUNG SIK; KIM, PIL HO; HAN, SOO BONG; RAGHAVENDRA, ACHARY; KIM, MEE HYEIN; LEE, CHONG KYO; SHIN, JIN SOO; (131 pag.)KR2015/25531; (2015); A;,
Benzothiophene – Wikipedia
Benzothiophene | C8H6S – PubChem