A Simple Synthesis of Alkyl 2-Aminobenzo[b]thiophene-3-carboxylates via an Unexpected Dehydrogenation of Alkyl 2-Amino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylates was written by Adib, Mehdi;Bayanati, Maryam;Soheilizad, Mehdi;Ghazvini, Helia Janatian;Tajbakhsh, Mahmood;Amanlou, Massoud. And the article was included in Synlett in 2014.Recommanded Product: 95211-67-9 The following contents are mentioned in the article:
A simple method for the preparation of alkyl 2-aminobenzo[b]thiophene-3-carboxylates is described. Alkyl 2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylates, generated from the Gewald three-component reaction between cyclohexanones, alkyl cyanoacetates, and sulfur, undergo dehydrogenation in benzonitrile under an air atm. to afford alkyl 2-aminobenzo[b]thiophene-3-carboxylates in good to excellent yields. This study involved multiple reactions and reactants, such as Ethyl 2-amino-4-methyl-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate (cas: 95211-67-9Recommanded Product: 95211-67-9).
Ethyl 2-amino-4-methyl-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate (cas: 95211-67-9) belongs to benzothiophene derivatives. Benzothiophene is relatively a stable molecule. The core structure is a part of various pharmaceutical substances and natural products. It is found within the chemical structures of pharmaceutical drugs such as raloxifene, zileuton, sertaconazole, and also BTCP.Recommanded Product: 95211-67-9
Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem