Cai, Aijie published the artcileRegio- and Enantioselective Preparation of Chiral Allylic Sulfones Featuring Elusive Quaternary Stereocenters, Product Details of C6H6OS, the main research area is regioselective enantioselective synthesis chiral allylic sulfone palladium catalyst; allylic substitution sodium sulfinate allylic carbonate palladium catalyst enantioselective; allylic sulfones; enantioselectivity; homogeneous catalysis; palladium; regioselectivity.
We describe here the first general asym. synthesis of sterically encumbered α,α-disubstituted allylic sulfones via Pd-catalyzed allylic substitution. The design and application of a new and highly efficient phosphoramidite ligand, I, proved to be crucial, and a wide variety of challenging allylic sulfones featuring quaternary stereocenters could be obtained in good yields and with good to excellent levels of regio- and enantioselectivities under attractive process conditions. The developed methodol. employs easily accessible chem. feedstock including racemic allylic precursors and sodium sulfinates. The utility of the method is further demonstrated by the synthesis of the sesquiterpene (-)-Agelasidine A (II).
Angewandte Chemie, International Edition published new progress about Allylic substitution reaction. 1468-83-3 belongs to class benzothiophene, name is 3-Acetylthiophene, and the molecular formula is C6H6OS, Product Details of C6H6OS.
Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem