Qin, Zemin published the artcileCo(II)-Catalyzed Oxidation of N,N-Dimethylaminoethanol: An Efficient Synthesis of Unsymmetrical (2,4-) and Symmetrical (2,6-) Diarylpyridines through Annulation of Aromatic Ketones with a Nitrogen Source, SDS of cas: 1468-83-3, the main research area is diarylpyridine preparation; aromatic ketone dimethylaminoethanol pseudo multicomponent one pot annulation.
An efficient and facile synthesis of 2,4- and 2,6-diarylpyridines has been developed. It involves one-pot [2+2+1+1] pseudo four-component annulation of aromatic ketones, a nitrogen source and a carbon donor. N,N-Dimethylaminoethanol is oxidized in the presence of Co(II) to provide a carbon synthon. Two C-C and two C-N bonds are formed during the oxidative annulation process. The products are strictly controlled due to the steric hindrance: 2,4-diarylpyridines are afforded effectively with small ketones while 2,6-diaryl analogs predominate when bulky ketones are employed.
Asian Journal of Organic Chemistry published new progress about Alkyl aryl ketones Role: RCT (Reactant), RACT (Reactant or Reagent). 1468-83-3 belongs to class benzothiophene, name is 3-Acetylthiophene, and the molecular formula is C6H6OS, SDS of cas: 1468-83-3.
Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem